Astelin and Fluid retention - a phase IV clinical study of FDA data

Summary:

Fluid retention is found among people who take Astelin, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Astelin and have Fluid retention. It is created by eHealthMe based on reports of 5,086 people who have side effects when taking Astelin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Aug, 18, 2022

5,086 people reported to have side effects when taking Astelin.
Among them, 37 people (0.73%) have Fluid retention.


What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,293 Astelin users for its effectiveness, alternative drugs and more.

What is Fluid retention?

Fluid retention (an abnormal accumulation of fluid in the blood) is found to be associated with 3,013 drugs and 2,209 conditions by eHealthMe.

Number of Astelin and Fluid retention reports submitted per year:

Could Astelin cause Fluid retention?

Time on Astelin when people have Fluid retention *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Fluid retention when taking Astelin *:

  • female: 78.79 %
  • male: 21.21 %

Age of people who have Fluid retention when taking Astelin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.69 %
  • 50-59: 46.15 %
  • 60+: 46.15 %

Common drugs people take besides Astelin *:

  1. Lasix: 22 people, 59.46%
  2. Lovenox: 10 people, 27.03%
  3. Zyrtec: 9 people, 24.32%
  4. Albuterol: 8 people, 21.62%
  5. Nasonex: 8 people, 21.62%
  6. Digoxin: 8 people, 21.62%
  7. Letairis: 8 people, 21.62%
  8. Singulair: 8 people, 21.62%
  9. Coumadin: 8 people, 21.62%
  10. Aciphex: 7 people, 18.92%

Common side effects people have besides Fluid retention *:

  1. Weight Increased: 18 people, 48.65%
  2. Oedema Peripheral (superficial swelling): 16 people, 43.24%
  3. Breathing Difficulty: 10 people, 27.03%
  4. Nausea (feeling of having an urge to vomit): 10 people, 27.03%
  5. Abdominal Pain: 9 people, 24.32%
  6. Fall: 9 people, 24.32%
  7. Joint Pain: 9 people, 24.32%
  8. Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 8 people, 21.62%
  9. Diarrhea: 8 people, 21.62%
  10. Fatigue (feeling of tiredness): 8 people, 21.62%

Common conditions people have *:

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 21.62%
  2. Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 10.81%
  3. Primary Myelofibrosis (primary disorder of the bone marrow): 4 people, 10.81%
  4. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 10.81%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 10.81%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.11%
  7. Hypersensitivity: 2 people, 5.41%
  8. Heart Rate Irregular: 2 people, 5.41%
  9. Type 2 Diabetes: 2 people, 5.41%
  10. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Astelin and have Fluid retention?

Check whether Fluid retention is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Fluid retention and when was it recovered:

Expand to all the drugs that have ingredients of azelastine hydrochloride:

Alternative drugs to, pros and cons of Astelin:

Common Astelin side effects:

Browse all side effects of Astelin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Fluid retention treatments and more:

COVID vaccines that are related to Fluid retention:

Common drugs associated with Fluid retention:

All the drugs that are associated with Fluid retention:

Common conditions associated with Fluid retention:

All the conditions that are associated with Fluid retention:

How the study uses the data?

The study uses data from the FDA. It is based on azelastine hydrochloride (the active ingredients of Astelin) and Astelin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: