Aubagio and Toxic skin eruption - a phase IV clinical study of FDA data


Toxic skin eruption is found among people who take Aubagio, especially for people who are female, 40-49 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Aubagio and have Toxic skin eruption. It is created by eHealthMe based on reports of 43,868 people who have side effects when taking Aubagio from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 20, 2023

43,868 people reported to have side effects when taking Aubagio.
Among them, 10 people (0.02%) have Toxic skin eruption.

What is Aubagio?

Aubagio has active ingredients of teriflunomide. It is often used in multiple sclerosis. eHealthMe is studying from 44,009 Aubagio users for its effectiveness, alternative drugs and more.

What is Toxic skin eruption?

Toxic skin eruption (skin breakdown due to toxic substance) is found to be associated with 1,110 drugs and 1,000 conditions by eHealthMe.

Number of Aubagio and Toxic skin eruption reports submitted per year:

Could Aubagio cause Toxic skin eruption?

Time on Aubagio when people have Toxic skin eruption *:

  • < 1 month: 37.5 %
  • 1 - 6 months: 37.5 %
  • 6 - 12 months: 12.5 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 12.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Toxic skin eruption when taking Aubagio *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Toxic skin eruption when taking Aubagio *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 50.0 %
  • 50-59: 37.5 %
  • 60+: 0.0 %

Common side effects people have besides Toxic skin eruption *:

  1. Itching: 6 people, 60.00%
  2. Rashes (redness): 5 people, 50.00%
  3. Drug Eruption (adverse drug reaction of the skin): 3 people, 30.00%
  4. Pain: 3 people, 30.00%
  5. Enanthema (rash formed inside the body): 3 people, 30.00%
  6. Erythema Multiforme (a type of hypersensitivity reaction): 3 people, 30.00%
  7. Rash Erythematous (redness of the skin): 2 people, 20.00%
  8. Eosinophilia (eosinophil count in the peripheral blood exceeds): 2 people, 20.00%
  9. Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 10.00%
  10. Escherichia Urinary Tract Infection (urinary tract infection by escherichia coli): 1 person, 10.00%

Common conditions people have *:

  1. Urinary Tract Infection: 1 person, 10.00%
  2. Tension Headache: 1 person, 10.00%
  3. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 10.00%
  4. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 1 person, 10.00%
  5. Birth Control: 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Aubagio and have Toxic skin eruption?

Check whether Toxic skin eruption is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Toxic skin eruption and when was it recovered:

Expand to all the drugs that have ingredients of teriflunomide:

Alternative drugs to, pros and cons of Aubagio:

Common Aubagio side effects:

Browse all side effects of Aubagio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Toxic skin eruption treatments and more:

COVID vaccines that are related to Toxic skin eruption:

Common drugs associated with Toxic skin eruption:

All the drugs that are associated with Toxic skin eruption:

Common conditions associated with Toxic skin eruption:

All the conditions that are associated with Toxic skin eruption:

How the study uses the data?

The study uses data from the FDA. It is based on teriflunomide (the active ingredients of Aubagio) and Aubagio (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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