Aubagio and Toxic skin eruption - a phase IV clinical study of FDA data

• Aubagio (44,009 reports)

• Abasia (inability to walk): 278 reports
• Abdominal discomfort: 1,080 reports
• Abdominal distension: 286 reports
• Abdominal pain: 586 reports
• Abdominal pain upper: 788 reports
• Acne (skin problems that cause pimples): 208 reports
• Activities of daily living impaired: 107 reports
• Adverse event: 141 reports
• Alanine aminotransferase increased: 191 reports
• Anaemia (lack of blood): 183 reports
• Ankle fracture: 126 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 796 reports
• Arrhythmias (irregular heartbeat): 118 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 186 reports
• Arthropathy: 164 reports
• Asthma: 159 reports
• Back pain: 1,137 reports
• Balance disorder: 1,914 reports
• Bladder disorder: 420 reports
• Blindness: 157 reports
• Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 179 reports
• Blood glucose increased: 228 reports
• Blood potassium decreased: 124 reports
• Blood pressure management: 105 reports
• Breast cancer: 159 reports
• Breathing difficulty: 888 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 362 reports
• Burning sensation: 680 reports
• Cardiac disorder: 110 reports
• Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 137 reports
• Cataract (clouding of the lens inside the eye): 119 reports
• Cellulitis (infection under the skin): 117 reports
• Central nervous system lesion (an abnormality in tissue of brain or spinal cord): 413 reports
• Chest pain: 603 reports
• Chills (felling of cold): 287 reports
• Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 633 reports
• Common peroneal nerve dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes): 223 reports
• Condition: 1,142 reports
• Confusional state: 385 reports
• Constipation: 546 reports
• Cough: 752 reports
• Crying: 142 reports
• Death: 270 reports
• Decreased interest: 309 reports
• Dehydration (dryness resulting from the removal of water): 306 reports
• Depressed mood: 729 reports
• Depression: 1,988 reports
• Diabetes: 149 reports
• Diarrhea: 5,234 reports
• Diplopia (double vision): 226 reports
• Discomfort: 171 reports
• Disturbance in attention: 224 reports
• Dizziness: 2,061 reports
• Drowsiness: 598 reports
• Drug hypersensitivity: 154 reports
• Drug ineffective: 2,543 reports
• Drug intolerance (drug sensitivity): 158 reports
• Dry mouth: 181 reports
• Dry skin: 305 reports
• Dysgraphia (impaired ability to learn to write): 173 reports
• Dyskinesia (abnormality or impairment of voluntary movement): 122 reports
• Dysstasia (difficulty in standing): 215 reports
• Eye disorder: 157 reports
• Eye pain: 154 reports
• Fainting (loss of consciousness and postural tone): 134 reports
• Fall: 3,312 reports
• Fatigue (feeling of tiredness): 5,357 reports
• Feeling cold: 107 reports
• Feeling hot: 252 reports
• Fever: 697 reports
• Flatulence (flatus expelled through the anus): 220 reports
• Foot fracture: 146 reports
• Fungal infection: 102 reports
• Gait disturbance: 2,679 reports
• Gastric disorder (disease of stomach): 177 reports
• Gastric ulcer (stomach ulcer): 115 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 152 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 469 reports
• General physical health deterioration (weak health status): 135 reports
• Haematochezia (passage of stools containing blood): 111 reports
• Hair loss: 6,663 reports
• Headache (pain in head): 3,157 reports
• Head discomfort: 101 reports
• Head injury: 711 reports
• Heart attack: 214 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 302 reports
• Heart rate increased: 271 reports
• Hemiparesis (weakness on one side of the body): 241 reports
• Hepatic enzyme increased: 674 reports
• Herpes zoster: 203 reports
• High blood cholesterol: 165 reports
• High blood pressure: 1,769 reports
• Hoarseness or changing voice: 139 reports
• Hospitalisation: 356 reports
• Hot flush (sudden feelings of heat): 283 reports
• Hyperhidrosis (abnormally increased sweating): 291 reports
• Hypersensitivity: 447 reports
• Hypoaesthesia (reduced sense of touch or sensation): 3,444 reports
• Hypokinesia (decreased bodily movement): 189 reports
• Hypotension (abnormally low blood pressure): 196 reports
• Ill-defined disorder: 151 reports
• Impaired driving ability: 132 reports
• Incontinence (lack of moderation or self-control): 186 reports
• Indigestion: 268 reports
• Infection: 295 reports
• Influenza like illness: 426 reports
• Insomnia (sleeplessness): 978 reports
• Intervertebral disc protrusion (spinal disc protrusion): 204 reports
• Itching: 1,162 reports
• Joint injury: 137 reports
• Joint pain: 885 reports
• Joint swelling: 237 reports
• Kidney infection: 112 reports
• Kidney stones: 217 reports
• Limb discomfort (discomfort in leg): 542 reports
• Limb injury: 117 reports
• Liver disorder (liver diseases): 127 reports
• Loss of consciousness: 316 reports
• Malaise (a feeling of general discomfort or uneasiness): 1,349 reports
• Memory loss: 2,032 reports
• Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 105 reports
• Micturition urgency (urgency to pass the urine): 196 reports
• Migraine (headache): 483 reports
• Mobility decreased (ability to move is reduced): 1,126 reports
• Mood swings (an extreme or rapid change in mood): 157 reports
• Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 334 reports
• Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2,146 reports
• Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5,118 reports
• Muscle aches (muscle pain): 422 reports
• Muscle spasms (muscle contraction): 1,076 reports
• Muscle spasticity (tight or stiff muscles and an inability to control those muscles): 359 reports
• Muscle tightness: 118 reports
• Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 111 reports
• Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 185 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 226 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 750 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 181 reports
• Nasopharyngitis (inflammation of the nasopharynx): 880 reports
• Nausea (feeling of having an urge to vomit): 3,048 reports
• Nausea and vomiting: 1,071 reports
• Neck pain: 198 reports
• Neuralgia (pain in one or more nerves): 251 reports
• Neuropathy peripheral (surface nerve damage): 484 reports
• Numbness and tingling (unusual prickling sensations): 129 reports
• Oedema peripheral (superficial swelling): 167 reports
• Optic neuritis (optic nerve inflammation): 269 reports
• Oropharyngeal pain: 259 reports
• Pain: 2,374 reports
• Pain in extremity: 1,794 reports
• Pancreatitis (inflammation of pancreas): 172 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3,065 reports
• Peripheral swelling: 579 reports
• Pneumonia: 609 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 312 reports
• Rashes (redness): 1,612 reports
• Rash pruritic (redness with itching): 178 reports
• Renal disorder (kidney disease): 106 reports
• Restless leg syndrome (a powerful urge to move your legs): 107 reports
• Road traffic accident: 168 reports
• Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 139 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 437 reports
• Sensory disturbance (sense disturbance): 248 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 165 reports
• Sinusitis (inflammation of sinus): 367 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 298 reports
• Skin discoloration: 180 reports
• Skin disorder (skin disease): 150 reports
• Skin exfoliation (removal of the oldest dead skin cells): 184 reports
• Sleep disorder: 363 reports
• Speech disorder: 394 reports
• Speech impairment (adult) (inability to speak (adult)): 316 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 112 reports
• Stress and anxiety: 1,171 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 259 reports
• Suicidal ideation: 115 reports
• Surgery: 286 reports
• Swallowing difficulty: 282 reports
• Swelling: 229 reports
• Taste - impaired: 138 reports
• Temperature intolerance (inability to go in temperature): 236 reports
• The flu (the flu is caused by an influenza virus): 492 reports
• Therapeutic response unexpected: 205 reports
• Thrombocytopenia (decrease of platelets in blood): 161 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 152 reports
• Tinnitus (a ringing in the ears): 117 reports
• Tooth abscess (pus formation in tooth): 107 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 787 reports
• Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation): 129 reports
• Upper respiratory tract infection: 141 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 404 reports
• Urinary retention (the inability to completely or partially empty the bladder): 128 reports
• Urinary tract infection: 1,378 reports
• Urination - painful: 133 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 291 reports
• Vision blurred: 647 reports
• Visual acuity reduced (reduced clearness of vision): 139 reports
• Visual impairment: 930 reports
• Weakness: 3,123 reports
• Weight decreased: 1,195 reports
• Weight increased: 387 reports
• White blood cell count decreased: 498 reports

• Toxic skin eruption (10,174 reports)

• Acetaminophen: 231 reports
• Aldactone: 128 reports
• Allopurinol: 492 reports
• Alprazolam: 159 reports
• Amlodipine: 261 reports
• Amoxicillin: 284 reports
• Aspirin: 175 reports
• Atarax: 251 reports
• Augmentin: 474 reports
• Augmentin '125': 229 reports
• Bactrim: 390 reports
• Bisoprolol fumarate: 107 reports
• Carboplatin: 121 reports
• Cordarone: 145 reports
• Crestor: 119 reports
• Depakene: 115 reports
• Dexamethasone: 109 reports
• Flagyl: 116 reports
• Fluconazole: 113 reports
• Furosemide: 399 reports
• Humira: 115 reports
• Ibu: 143 reports
• Ibuprofen: 143 reports
• Keppra: 136 reports
• Lamictal: 293 reports
• Lansoprazole: 248 reports
• Lasix: 273 reports
• Levothyroxine sodium: 113 reports
• Lopurin: 492 reports
• Lovenox: 255 reports
• Lyrica: 192 reports
• Metformin: 251 reports
• Methotrexate: 232 reports
• Nexium: 212 reports
• Omeprazole: 304 reports
• Pantoprazole: 314 reports
• Paracetamol: 298 reports
• Plavix: 236 reports
• Prednisolone: 204 reports
• Prednisone: 189 reports
• Profen: 143 reports
• Ramipril: 166 reports
• Rebetol: 128 reports
• Revlimid: 152 reports
• Ribavirin: 143 reports
• Tegretol: 200 reports
• Tramadol: 157 reports
• Velcade: 105 reports
• Zolpidem: 122 reports

All the drugs that are associated with Toxic skin eruption:

• Toxic skin eruption (1,110 drugs)

• Acute myeloid leukaemia: 106 reports
• Agrypnia: 136 reports
• Antidepressant therapy: 213 reports
• Anxiety: 116 reports
• Anxiety aggravated: 116 reports
• Atrial fibrillation: 160 reports
• Atrial fibrillation/flutter: 166 reports
• Auricular fibrillation: 160 reports
• Breast cancer: 134 reports
• Cystitis aggravated: 111 reports
• Depression: 213 reports
• Diabetes: 153 reports
• Diabetes mellitus: 155 reports
• Epilepsy: 296 reports
• Feeling uptight: 116 reports
• Fever: 120 reports
• Hbp: 715 reports
• Hepatitis c: 222 reports
• High blood cholesterol: 123 reports
• High blood pressure: 715 reports
• Hiv: 201 reports
• Hiv infection: 201 reports
• Human immunodeficiency virus infection: 201 reports
• Hypertension: 718 reports
• Hyperuricaemia: 140 reports
• Hypnosis and pain: 210 reports
• Low thyroid: 101 reports
• Multiple myeloma: 209 reports
• Niddm: 135 reports
• Pain: 211 reports
• Preventive health care: 187 reports
• Ra: 208 reports
• Rheumatoid arthritis: 212 reports
• Sleeping difficulty: 136 reports
• Type 2 diabetes: 135 reports

All the conditions that are associated with Toxic skin eruption:

• Toxic skin eruption (1,000 conditions)

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