Augmentin '125' and Reflux oesophagitis - a phase IV clinical study of FDA data


Reflux oesophagitis is found among people who take Augmentin '125', especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Augmentin '125' and have Reflux oesophagitis. It is created by eHealthMe based on reports of 10,373 people who have side effects when taking Augmentin '125' from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 12, 2022

10,373 people reported to have side effects when taking Augmentin '125'.
Among them, 10 people (0.1%) have Reflux oesophagitis.

What is Augmentin '125'?

Augmentin '125' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 10,452 Augmentin '125' users for its effectiveness, alternative drugs and more.

What is Reflux oesophagitis?

Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus) is found to be associated with 858 drugs and 521 conditions by eHealthMe.

Number of Augmentin '125' and Reflux oesophagitis reports submitted per year:

Could Augmentin '125' cause Reflux oesophagitis?

Time on Augmentin '125' when people have Reflux oesophagitis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Reflux oesophagitis when taking Augmentin '125' *:

  • female: 20 %
  • male: 80 %

Age of people who have Reflux oesophagitis when taking Augmentin '125' *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 40 %
  • 50-59: 0.0 %
  • 60+: 60 %

Common drugs people take besides Augmentin '125' *:

  1. Xanax: 5 people, 50.00%
  2. Ibuprofen: 3 people, 30.00%
  3. Lamisil: 3 people, 30.00%
  4. Serevent: 3 people, 30.00%
  5. Plavix: 3 people, 30.00%
  6. Ambien: 3 people, 30.00%
  7. Cardizem: 2 people, 20.00%
  8. Effexor Xr: 2 people, 20.00%
  9. Norvasc: 2 people, 20.00%
  10. Nitro-Dur: 2 people, 20.00%

Common side effects people have besides Reflux oesophagitis *:

  1. Stable Angina (a constant chest pain): 5 people, 50.00%
  2. Chest Pain: 4 people, 40.00%
  3. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 4 people, 40.00%
  4. Breathing Difficulty: 4 people, 40.00%
  5. Ageusia (loss of taste functions of the tongue): 3 people, 30.00%
  6. Nausea And Vomiting: 3 people, 30.00%
  7. Gastroenteritis Bacterial (inflammation of stomach and intestine by bacterial infection): 3 people, 30.00%
  8. Type 2 Diabetes: 3 people, 30.00%
  9. Headache (pain in head): 3 people, 30.00%
  10. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 30.00%

Common conditions people have *:

  1. Stress And Anxiety: 3 people, 30.00%
  2. Nail Tinea (fungal infection of nail): 3 people, 30.00%
  3. Gastroenteritis (inflammation of stomach and intestine): 3 people, 30.00%
  4. Oedema (fluid collection in tissue): 2 people, 20.00%
  5. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 20.00%
  6. Wound: 1 person, 10.00%
  7. Swelling: 1 person, 10.00%
  8. Sleep Disorder: 1 person, 10.00%
  9. Insomnia (sleeplessness): 1 person, 10.00%
  10. Hypersensitivity: 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin '125' and have Reflux oesophagitis?

Check whether Reflux oesophagitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Reflux oesophagitis and when was it recovered:

Expand to all the drugs that have ingredients of amoxicillin; clavulanate potassium:

Alternative drugs to, pros and cons of Augmentin '125':

Common Augmentin '125' side effects:

Browse all side effects of Augmentin '125':

a b c d e f g h i j k l m n o p q r s t u v w x y z

Reflux oesophagitis treatments and more:

COVID vaccines that are related to Reflux oesophagitis:

Common drugs associated with Reflux oesophagitis:

All the drugs that are associated with Reflux oesophagitis:

Common conditions associated with Reflux oesophagitis:

All the conditions that are associated with Reflux oesophagitis:

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Augmentin '125') and Augmentin '125' (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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