Augmentin '500' and Ulcerative colitis - a phase IV clinical study of FDA data


Ulcerative colitis is found among people who take Augmentin '500', especially for people who are female, 40-49 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Augmentin '500' and have Ulcerative colitis. It is created by eHealthMe based on reports of 319 people who have side effects when taking Augmentin '500' from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 26, 2022

319 people reported to have side effects when taking Augmentin '500'.
Among them, 6 people (1.88%) have Ulcerative colitis.

What is Augmentin '500'?

Augmentin '500' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 508 Augmentin '500' users for its effectiveness, alternative drugs and more.

What is Ulcerative colitis?

Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine) is found to be associated with 2,399 drugs and 1,841 conditions by eHealthMe.

Number of Augmentin '500' and Ulcerative colitis reports submitted per year:

Could Augmentin '500' cause Ulcerative colitis?

Time on Augmentin '500' when people have Ulcerative colitis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Ulcerative colitis when taking Augmentin '500' *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Ulcerative colitis when taking Augmentin '500' *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 33.33 %
  • 30-39: 0.0 %
  • 40-49: 66.67 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Common drugs people take besides Augmentin '500' *:

  1. Zometa: 4 people, 66.67%
  2. Simvastatin: 4 people, 66.67%
  3. Reglan: 4 people, 66.67%
  4. Protonix: 4 people, 66.67%
  5. Demerol: 4 people, 66.67%
  6. Lac-Hydrin: 2 people, 33.33%
  7. Emla: 2 people, 33.33%
  8. Desoxyn: 2 people, 33.33%
  9. Dilaudid: 2 people, 33.33%
  10. Lidocaine: 2 people, 33.33%

Common side effects people have besides Ulcerative colitis *:

  1. Diarrhea: 5 people, 83.33%
  2. Oesophagitis (inflammation of oesophagus): 4 people, 66.67%
  3. Stress And Anxiety: 4 people, 66.67%
  4. Renal Failure Chronic (long lasting kidney dysfunction): 4 people, 66.67%
  5. Chest Pain: 4 people, 66.67%
  6. Nausea (feeling of having an urge to vomit): 4 people, 66.67%
  7. Nausea And Vomiting: 4 people, 66.67%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 66.67%
  9. Intervertebral Disc Protrusion (spinal disc protrusion): 4 people, 66.67%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 66.67%

Common conditions people have *:

  1. Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 33.33%
  2. Metastases To Bone (cancer spreads to bone): 2 people, 33.33%
  3. Acne (skin problems that cause pimples): 2 people, 33.33%
  4. Hypersensitivity: 1 person, 16.67%
  5. Birth Control: 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin '500' and have Ulcerative colitis?

Check whether Ulcerative colitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Ulcerative colitis and when was it recovered:

Expand to all the drugs that have ingredients of amoxicillin; clavulanate potassium:

Alternative drugs to, pros and cons of Augmentin '500':

Ulcerative colitis treatments and more:

COVID vaccines that are related to Ulcerative colitis:

Common drugs associated with Ulcerative colitis:

All the drugs that are associated with Ulcerative colitis:

Common conditions associated with Ulcerative colitis:

All the conditions that are associated with Ulcerative colitis:

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Augmentin '500') and Augmentin '500' (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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