Avalide and Thrombotic thrombocytopenic purpura - a phase IV clinical study of FDA data


Thrombotic thrombocytopenic purpura is reported only by a few people who take Avalide.

The phase IV clinical study analyzes which people take Avalide and have Thrombotic thrombocytopenic purpura. It is created by eHealthMe based on reports of 5,529 people who have side effects while taking Avalide from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 14, 2022

5,529 people reported to have side effects when taking Avalide.
Among them, 2 people (0.04%) have Thrombotic thrombocytopenic purpura.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,827 Avalide users for its effectiveness, alternative drugs and more.

What is Thrombotic thrombocytopenic purpura?

Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body) is found to be associated with 1,152 drugs and 753 conditions by eHealthMe.

Number of Avalide and Thrombotic thrombocytopenic purpura reports submitted per year:

Could Avalide cause Thrombotic thrombocytopenic purpura?

Gender of people who have Thrombotic thrombocytopenic purpura when taking Avalide *:

  • female: 100 %
  • male: 0.0 %

Common drugs people take besides Avalide *:

  1. Tylenol: 1 person, 50.00%
  2. Toprol-Xl: 1 person, 50.00%
  3. Sonata: 1 person, 50.00%
  4. Nexium: 1 person, 50.00%
  5. Lyrica: 1 person, 50.00%
  6. Dynacirc: 1 person, 50.00%
  7. Aspirin: 1 person, 50.00%

Common side effects people have besides Thrombotic thrombocytopenic purpura *:

  1. Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 50.00%
  2. Neck Pain: 1 person, 50.00%
  3. Nausea (feeling of having an urge to vomit): 1 person, 50.00%
  4. Insomnia (sleeplessness): 1 person, 50.00%
  5. Headache (pain in head): 1 person, 50.00%
  6. Confusional State: 1 person, 50.00%
  7. Cerebellar Infarction (impaired blood circulation to cerebellum): 1 person, 50.00%
  8. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 1 person, 50.00%
  9. Acute Kidney Failure: 1 person, 50.00%
  10. Abdominal Pain: 1 person, 50.00%

Common conditions people have *:

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Avalide and have Thrombotic thrombocytopenic purpura?

Check whether Thrombotic thrombocytopenic purpura is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Thrombotic thrombocytopenic purpura and when was it recovered:

Expand to all the drugs that have ingredients of hydrochlorothiazide; irbesartan:

Alternative drugs to, pros and cons of Avalide:

Common Avalide side effects:

Browse all side effects of Avalide:

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Thrombotic thrombocytopenic purpura treatments and more:

COVID vaccines that are related to Thrombotic thrombocytopenic purpura:

Common drugs associated with Thrombotic thrombocytopenic purpura:

All the drugs that are associated with Thrombotic thrombocytopenic purpura:

Common conditions associated with Thrombotic thrombocytopenic purpura:

All the conditions that are associated with Thrombotic thrombocytopenic purpura:

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; irbesartan (the active ingredients of Avalide) and Avalide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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