Avandia and Heart attack - a phase IV clinical study of FDA data
Summary:
Heart attack is found among people who take Avandia, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years.
The phase IV clinical study analyzes which people take Avandia and have Heart attack. It is created by eHealthMe based on reports of 141,784 people who have side effects when taking Avandia from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
141,784 people reported to have side effects when taking Avandia.
Among them, 53,017 people (37.39%) have Heart attack.
What is Avandia?
Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 141,948 Avandia users for its effectiveness, alternative drugs and more.
What is Heart attack?
Heart attack is found to be associated with 3,706 drugs and 3,169 conditions by eHealthMe.
Number of Avandia and Heart attack reports submitted per year:

Time on Avandia when people have Heart attack *:
Gender of people who have Heart attack when taking Avandia*:
Age of people who have Heart attack when taking Avandia *:
Common drugs people take besides Avandia *:
Common side effects people have besides Heart attack *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Avandia and have Heart attack?
Check whether Heart attack is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Heart attack and when was it recovered:
Expand to all the drugs that have ingredients of rosiglitazone maleate:
- Heart attack and drugs with ingredients of rosiglitazone maleate (54,020 reports)
Alternative drugs to, pros and cons of Avandia:
- Avandia (141,948 reports)
Common Avandia side effects:
- Heart attack: 53,017 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 22,484 reports
- Coronary heart disease (narrowing or blockage of the coronary arteries): 12,047 reports
- Death: 7,494 reports
Browse all side effects of Avandia:
a b c d e f g h i j k l m n o p q r s t u v w x y zHeart attack treatments and more:
- Heart attack (252,018 reports)
COVID vaccines that are related to Heart attack:
- Heart attack in Moderna COVID Vaccine
- Heart attack in Pfizer BioNTech Covid Vaccine
- Heart attack in Johnson and Johnson Covid Vaccine
Common drugs associated with Heart attack:
- Avandia: 53,017 reports
- Vioxx: 33,541 reports
- Aspirin: 15,813 reports
- Plavix: 9,606 reports
- Lipitor: 9,141 reports
- Celebrex: 9,103 reports
- Lisinopril: 7,057 reports
- Metformin: 6,826 reports
- Lasix: 5,741 reports
- Prednisone: 5,560 reports
All the drugs that are associated with Heart attack:
- Heart attack (3,706 drugs)
Common conditions associated with Heart attack:
- Diabetes: 46,451 reports
- Rheumatoid arthritis: 8,562 reports
- Arthritis: 7,642 reports
- High blood pressure: 7,474 reports
- Pain: 6,842 reports
All the conditions that are associated with Heart attack:
- Heart attack (3,169 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on rosiglitazone maleate (the active ingredients of Avandia) and Avandia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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