Avandia and Myocardial ischaemia - a phase IV clinical study of FDA data

Summary:

We study 141,978 people who have side effects when taking Avandia. Myocardial ischaemia is found, especially among people who are male, 60+ old, have been taking the drug for 2 - 5 years, also take Avandamet and have Depression.

The phase IV clinical study analyzes which people take Avandia and have Myocardial ischaemia. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 08, 2023

141,978 people reported to have side effects when taking Avandia.
Among them, 3,823 people (2.69%) have Myocardial ischaemia.

What is Avandia?

Avandia has active ingredients of rosiglitazone maleate. It is used in diabetes. Currently, eHealthMe is studying from 142,142 Avandia users.

What is Myocardial ischaemia?

Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased) is found to be associated with 1,767 drugs and 973 conditions by eHealthMe. Currently, we are studying 27,774 people who have Myocardial ischaemia.

Number of Avandia and Myocardial ischaemia reports submitted per year:

Could Avandia cause Myocardial ischaemia?

* Approximation only. Some reports may have incomplete information.

Do you take Avandia and have Myocardial ischaemia?

Check whether Myocardial ischaemia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Avandia side effects by duration, gender and age:

Avandia side effects (142,142 reports)

Myocardial ischaemia treatments and more:

Myocardial ischaemia (27,774 reports)

Common drugs associated with Myocardial ischaemia:

All the drugs that are associated with Myocardial ischaemia:

Myocardial ischaemia (1,767 drugs)

Common conditions associated with Myocardial ischaemia:

All the conditions that are associated with Myocardial ischaemia:

Myocardial ischaemia (973 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rosiglitazone maleate (the active ingredients of Avandia) and Avandia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.