Avastin and Renal tubular acidosis - a phase IV clinical study of FDA data

Summary:

Renal tubular acidosis is found among people who take Avastin, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Avastin and have Renal tubular acidosis. It is created by eHealthMe based on reports of 69,252 people who have side effects when taking Avastin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Nov, 30, 2022

69,252 people reported to have side effects when taking Avastin.
Among them, 7 people (0.01%) have Renal tubular acidosis.


What is Avastin?

Avastin has active ingredients of bevacizumab. It is often used in macular degeneration. eHealthMe is studying from 69,850 Avastin users for its effectiveness, alternative drugs and more.

What is Renal tubular acidosis?

Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys) is found to be associated with 693 drugs and 391 conditions by eHealthMe.

Number of Avastin and Renal tubular acidosis reports submitted per year:

Could Avastin cause Renal tubular acidosis?

Time on Avastin when people have Renal tubular acidosis *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Renal tubular acidosis when taking Avastin *:

  • female: 85.71 %
  • male: 14.29 %

Age of people who have Renal tubular acidosis when taking Avastin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 0.0 %
  • 60+: 83.33 %

Common drugs people take besides Avastin *:

  1. Motrin: 3 people, 42.86%
  2. Megace: 3 people, 42.86%
  3. Leucovorin Calcium: 2 people, 28.57%
  4. Doral: 2 people, 28.57%
  5. Fluorouracil: 2 people, 28.57%
  6. Kytril: 2 people, 28.57%
  7. Zeaxanthin: 1 person, 14.29%
  8. Cardizem: 1 person, 14.29%
  9. Darvocet: 1 person, 14.29%
  10. Decadron: 1 person, 14.29%

Common side effects people have besides Renal tubular acidosis *:

  1. Perirectal Abscess: 3 people, 42.86%
  2. Blood Bicarbonate Decreased: 3 people, 42.86%
  3. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 3 people, 42.86%
  4. Weakness: 3 people, 42.86%
  5. Diarrhea: 3 people, 42.86%
  6. Culture Wound Positive: 3 people, 42.86%
  7. Confusional State: 3 people, 42.86%
  8. Oedema Peripheral (superficial swelling): 3 people, 42.86%
  9. Escherichia Infection (bacterial infection by escherichia coli): 3 people, 42.86%
  10. Cardiac Failure Congestive: 3 people, 42.86%

Common conditions people have *:

  1. Metastatic Gastric Cancer (cancer types can spread to the stomach from other place): 3 people, 42.86%
  2. Rectal Cancer Metastatic (cancer of rectum spreads to other): 1 person, 14.29%
  3. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 14.29%
  4. Large Intestine Carcinoma (cancer of large intestine): 1 person, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Avastin and have Renal tubular acidosis?

Check whether Renal tubular acidosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Renal tubular acidosis and when was it recovered:

Expand to all the drugs that have ingredients of bevacizumab:

Alternative drugs to, pros and cons of Avastin:

Common Avastin side effects:

Browse all side effects of Avastin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Renal tubular acidosis treatments and more:

COVID vaccines that are related to Renal tubular acidosis:

Common drugs associated with Renal tubular acidosis:

All the drugs that are associated with Renal tubular acidosis:

Common conditions associated with Renal tubular acidosis:

All the conditions that are associated with Renal tubular acidosis:

How the study uses the data?

The study uses data from the FDA. It is based on bevacizumab (the active ingredients of Avastin) and Avastin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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