Benadryl and Tonic clonic movements - a phase IV clinical study of FDA data

• Benadryl (89,721 reports)

• Abasia (inability to walk): 179 reports
• Abdominal discomfort: 1,627 reports
• Abdominal distension: 1,084 reports
• Abdominal pain: 2,863 reports
• Abdominal pain lower: 199 reports
• Abdominal pain upper: 1,919 reports
• Abnormal behavior: 252 reports
• Abnormal dreams: 162 reports
• Abortion spontaneous (naturally occurring miscarriage): 122 reports
• Abscess (pus): 279 reports
• Accidental overdose (therapeutic agent): 166 reports
• Acne (skin problems that cause pimples): 494 reports
• Activated partial thromboplastin time prolonged: 102 reports
• Activities of daily living impaired: 213 reports
• Acute kidney failure: 1,829 reports
• Acute myocardial infarction (acute heart attack): 132 reports
• Acute respiratory failure: 169 reports
• Acute upper airway obstruction (blockage occurs in the upper airway): 162 reports
• Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids): 148 reports
• Adverse drug reaction: 447 reports
• Adverse event: 389 reports
• Ageusia (loss of taste functions of the tongue): 133 reports
• Aggression: 291 reports
• Agitation (state of anxiety or nervous excitement): 1,049 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1,107 reports
• Alanine aminotransferase increased: 859 reports
• Allergic rhinitis: 103 reports
• Anaemia (lack of blood): 2,249 reports
• Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation): 111 reports
• Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 1,612 reports
• Anger: 194 reports
• Angioedema (rapid swelling of the dermis): 514 reports
• Anhedonia (inability to experience pleasure from activities usually found enjoyable): 452 reports
• Ankle fracture: 184 reports
• Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 201 reports
• Aortic arteriosclerosis (hardening of the aortic arteries): 145 reports
• Aphonia (inability to produce voice): 173 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 2,118 reports
• Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 268 reports
• Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 129 reports
• Arrhythmias (irregular heartbeat): 1,793 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 1,129 reports
• Arthropathy: 713 reports
• Arthropod bite: 164 reports
• Ascites (accumulation of fluid in the abdominal cavity): 299 reports
• Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 257 reports
• Aspartate aminotransferase increased: 801 reports
• Asthma: 1,263 reports
• Atelectasis (partial or complete collapse of the lung): 451 reports
• Atherosclerosis (disorder of the arteries): 227 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 877 reports
• Back disorder: 131 reports
• Back injury: 129 reports
• Back pain: 3,346 reports
• Bacteraemia (presence of bacteria in the blood): 138 reports
• Bacterial infection: 229 reports
• Bacterial test positive: 163 reports
• Balance disorder: 946 reports
• Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 336 reports
• Belching (release of gas from the digestive tract): 113 reports
• Bipolar disorder (mood disorder): 115 reports
• Bladder disorder: 132 reports
• Bleeding disorders: 114 reports
• Bleeding into the skin: 179 reports
• Blindness: 199 reports
• Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 651 reports
• Blood albumin decreased: 158 reports
• Blood alkaline phosphatase increased: 294 reports
• Blood bilirubin increased: 337 reports
• Blood calcium decreased: 219 reports
• Blood creatine phosphokinase increased: 138 reports
• Blood creatinine decreased: 103 reports
• Blood creatinine increased: 621 reports
• Blood glucose decreased: 248 reports
• Blood glucose increased: 957 reports
• Blood iron decreased: 157 reports
• Blood lactate dehydrogenase increased: 184 reports
• Blood magnesium decreased: 251 reports
• Blood potassium decreased: 397 reports
• Blood pressure diastolic decreased: 748 reports
• Blood pressure diastolic increased: 403 reports
• Blood pressure fluctuation: 1,999 reports
• Blood pressure management: 283 reports
• Blood pressure systolic decreased: 141 reports
• Blood pressure systolic increased: 2,011 reports
• Blood sodium decreased: 184 reports
• Blood thyroid stimulating hormone increased: 132 reports
• Blood urea increased: 208 reports
• Blood urine present: 493 reports
• Body temperature decreased: 708 reports
• Body temperature increased: 658 reports
• Bone density decreased: 172 reports
• Bone disorder: 565 reports
• Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 216 reports
• Bone marrow failure: 105 reports
• Bone pain: 790 reports
• Bradycardia (abnormally slow heart action): 470 reports
• Breast cancer: 143 reports
• Breast lump (localized swelling that feels different from the surrounding breast tissue): 106 reports
• Breast pain: 129 reports
• Breathing difficulty: 7,184 reports
• Breathing - slowed or stopped: 249 reports
• Breath sounds: 103 reports
• Broken bone: 157 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1,342 reports
• Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 288 reports
• Burning sensation: 975 reports
• Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 226 reports
• Candidiasis (candidiasis or thrush is a fungal infection): 155 reports
• Canker sores (painful, open sore in the mouth): 123 reports
• Cardiac arrest: 456 reports
• Cardiac disorder: 598 reports
• Cardiac failure: 215 reports
• Cardiac failure congestive: 680 reports
• Cardiac murmur (an heart sound in valve abnormality): 179 reports
• Cardiomyopathy (weakening of the heart muscle): 221 reports
• Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 328 reports
• Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 203 reports
• Cataract (clouding of the lens inside the eye): 553 reports
• Cellulitis (infection under the skin): 810 reports
• Central nervous system lesion (an abnormality in tissue of brain or spinal cord): 110 reports
• Cerebral infarction (less blood supply to brain resulting tissue damage): 127 reports
• Chest pain: 4,887 reports
• Chills (felling of cold): 2,765 reports
• Cholecystitis (infection of gallbladder): 139 reports
• Cholecystitis chronic (long lasting infection of gallbladder): 126 reports
• Chronic kidney disease: 2,078 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 598 reports
• Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 174 reports
• Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 454 reports
• Colitis (inflammation of colon): 430 reports
• Completed suicide (act of taking one's own life): 117 reports
• Compression fracture (fracture due to pressure caused by injury): 146 reports
• Concussion (short loss of normal brain function in response to a head injury): 110 reports
• Confusion: 434 reports
• Confusional state: 1,115 reports
• Conjunctivitis (pink eye): 210 reports
• Consciousness - decreased: 441 reports
• Constipation: 2,221 reports
• Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 576 reports
• Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly): 125 reports
• Coronary heart disease (narrowing or blockage of the coronary arteries): 253 reports
• Cough: 4,206 reports
• Coughing up blood: 293 reports
• C-reactive protein increased: 625 reports
• Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 589 reports
• Crying: 373 reports
• Crystal urine present: 126 reports
• Culture urine positive: 179 reports
• Cuts and puncture wounds: 185 reports
• Cyst (a closed sac): 239 reports
• Death: 2,439 reports
• Decreased activity: 105 reports
• Decreased interest: 179 reports
• Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 769 reports
• Deformity (disfigurement): 255 reports
• Dehydration (dryness resulting from the removal of water): 1,743 reports
• Delirium (wild excitement): 217 reports
• Delusion (a false belief or opinion): 104 reports
• Dementia (madness): 123 reports
• Dental caries: 386 reports
• Depressed level of consciousness: 219 reports
• Depressed mood: 373 reports
• Depression: 2,474 reports
• Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 449 reports
• Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 161 reports
• Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 157 reports
• Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens): 169 reports
• Device related infection: 236 reports
• Diabetes: 720 reports
• Diabetes mellitus inadequate control: 123 reports
• Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 122 reports
• Diarrhea: 5,616 reports
• Diarrhea haemorrhagic: 123 reports
• Diplopia (double vision): 335 reports
• Disability: 237 reports
• Discomfort: 642 reports
• Disease progression: 691 reports
• Disease recurrence: 164 reports
• Disturbance in attention: 403 reports
• Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 332 reports
• Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 203 reports
• Dizziness: 5,141 reports
• Drowsiness: 3,160 reports
• Drug abuse and dependence: 182 reports
• Drug administration error: 153 reports
• Drug dependence: 330 reports
• Drug effect decreased: 328 reports
• Drug eruption (adverse drug reaction of the skin): 279 reports
• Drug exposure during pregnancy: 203 reports
• Drug hypersensitivity: 2,674 reports
• Drug ineffective: 5,423 reports
• Drug intolerance (drug sensitivity): 955 reports
• Drug level below therapeutic: 161 reports
• Drug specific antibody present: 163 reports
• Drug toxicity: 165 reports
• Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 313 reports
• Dry eyes (lack of adequate tears): 448 reports
• Dry mouth: 982 reports
• Dry skin: 928 reports
• Dry throat: 164 reports
• Dyskinesia (abnormality or impairment of voluntary movement): 400 reports
• Dyslipidaemia (abnormal amount of lipids): 104 reports
• Dyspnea exertional: 522 reports
• Dysstasia (difficulty in standing): 240 reports
• Ear discomfort: 188 reports
• Ear pain: 473 reports
• Eating disorder: 274 reports
• Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 148 reports
• Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 519 reports
• Ejection fraction decreased (systolic heart failure): 157 reports
• Electrocardiogram qt prolonged: 157 reports
• Emotional disorder: 269 reports
• Emotional distress: 984 reports
• Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 222 reports
• Encephalopathy (functioning of the brain is affected by some agent or condition): 147 reports
• Enlarged heart: 357 reports
• Enthesopathy (disorder of entheses (bone attachments)): 360 reports
• Eosinophil count increased: 168 reports
• Erection problems: 140 reports
• Erythema multiforme (a type of hypersensitivity reaction): 235 reports
• Excoriation (to tear or wear off the skin of): 101 reports
• Exostosis (formation of new bone on the surface of a bone): 265 reports
• Extrapyramidal disorder (involuntary muscle spasms in the face and neck): 137 reports
• Eye disorder: 254 reports
• Eye infection: 184 reports
• Eye irritation: 276 reports
• Eyelid oedema (eyelids are swollen and contain excessive fluid): 148 reports
• Eye pain: 513 reports
• Eye pruritus (eye itching): 398 reports
• Eye swelling: 660 reports
• Face oedema (swelling of face): 253 reports
• Facial pain: 207 reports
• Faecal incontinence (a lack of control over passing stool): 149 reports
• Faeces discolored: 148 reports
• Failure to thrive (inadequate weight gain and physical growth in children): 117 reports
• Fainting (loss of consciousness and postural tone): 1,001 reports
• Fall: 3,066 reports
• Fatigue (feeling of tiredness): 9,979 reports
• Fear: 323 reports
• Febrile neutropenia (fever with reduced white blood cells): 701 reports
• Feeding disorder (when children refuse to eat certain food groups): 186 reports
• Feeling cold: 524 reports
• Feeling hot: 1,230 reports
• Feeling jittery: 190 reports
• Femur fracture: 251 reports
• Fever: 4,891 reports
• Fibromyalgia (a long-term condition which causes pain all over the body): 555 reports
• Fistula (an abnormal connection or passageway between two): 249 reports
• Flank pain (a distressing sensation experienced around the lower back and the upper abdomen): 195 reports
• Flatulence (flatus expelled through the anus): 433 reports
• Fluid overload (too much fluid in the blood): 145 reports
• Fluid retention (an abnormal accumulation of fluid in the blood): 401 reports
• Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 126 reports
• Food allergy: 227 reports
• Foot deformity (functional disability of foot): 191 reports
• Foot fracture: 290 reports
• Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin): 123 reports
• Full blood count decreased: 141 reports
• Fungal infection: 410 reports
• Fungal nail infection: 130 reports
• Furuncle (infection of the hair follicle): 101 reports
• Gait disturbance: 1,791 reports
• Gallbladder disorder: 270 reports
• Gallstones (stone formation by bile component): 545 reports
• Gastric disorder (disease of stomach): 424 reports
• Gastric ulcer (stomach ulcer): 738 reports
• Gastritis (inflammation of stomach): 425 reports
• Gastroenteritis (inflammation of stomach and intestine): 241 reports
• Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection): 295 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1,451 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 535 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 486 reports
• Gastrointestinal inflammation (inflammation of stomach and intestine): 103 reports
• Gastrointestinal pain: 106 reports
• Generalised erythema (redness of the skin all over the body): 147 reports
• Generalised oedema (swelling all over the body): 115 reports
• General physical health deterioration (weak health status): 825 reports
• Gingival bleeding (bleeding gums): 209 reports
• Gingival disorder (gum disease): 148 reports
• Gingival pain (gum pain): 185 reports
• Gingivitis (inflammation of gums): 134 reports
• Glaucoma (increased fluid pressure in the eye with vision loss): 177 reports
• Glossodynia (a burning or painful sensation in the tongue): 182 reports
• Gout (uric acid crystals building up in the body): 242 reports
• Grand mal convulsion (a type of generalized seizure that affects the entire brain): 127 reports
• Granuloma skin (a small area of inflammation on skin due to tissue injury): 206 reports
• Groin pain: 155 reports
• Gums - swollen: 157 reports
• Haematemesis (vomiting of blood): 211 reports
• Haematochezia (passage of stools containing blood): 585 reports
• Haematocrit decreased: 653 reports
• Haematoma (collection of blood outside the blood vessels): 178 reports
• Haematuria (presence of blood in urine): 335 reports
• Haemoglobin decreased: 1,387 reports
• Haemolytic anaemia (anaemia due to haemolysis): 119 reports
• Haemorrhage (bleeding): 652 reports
• Haemorrhoids (a swollen vein or group of veins in the region of the anus): 444 reports
• Hair color changes: 303 reports
• Hair disorder: 238 reports
• Hair loss: 1,880 reports
• Hallucination, auditory (perceiving sounds without auditory stimulus): 127 reports
• Hallucinations (sensations that appear real but are created by your mind): 637 reports
• Hallucination, visual (seeing things that aren't there): 176 reports
• Headache (pain in head): 7,794 reports
• Head discomfort: 141 reports
• Head injury: 1,693 reports
• Hearing loss: 219 reports
• Heart attack: 857 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 1,455 reports
• Heart rate decreased: 1,419 reports
• Heart rate increased: 2,580 reports
• Heart rate irregular: 778 reports
• Heavy or prolong menstrual bleeding: 135 reports
• Hemiparesis (weakness on one side of the body): 203 reports
• Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 126 reports
• Hepatic cyst: 157 reports
• Hepatic enzyme increased: 617 reports
• Hepatic failure (liver failure): 182 reports
• Hepatic steatosis (fatty liver disease): 268 reports
• Hepatitis (inflammation of the liver): 178 reports
• Hepatomegaly (abnormal enlargement of the liver): 173 reports
• Hepatotoxicity (chemical-driven liver damage): 106 reports
• Hereditary angioedema (recurrent episodes of severe swelling): 260 reports
• Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 230 reports
• Herpes simplex (herpes simplex is a common viral infection): 124 reports
• Herpes zoster: 1,080 reports
• Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 312 reports
• High blood cholesterol: 979 reports
• High blood pressure: 6,173 reports
• Hip fracture: 248 reports
• Hoarseness or changing voice: 645 reports
• Hospitalisation: 405 reports
• Hot flush (sudden feelings of heat): 920 reports
• Hyperaesthesia: 140 reports
• Hypercalcaemia (elevated calcium (ca+) level in the blood): 328 reports
• Hyperglycemia (high blood sugar): 332 reports
• Hyperhidrosis (abnormally increased sweating): 1,473 reports
• Hyperkalemia (damage to or disease of the kidney): 275 reports
• Hyperlipidaemia (presence of excess lipids in the blood): 229 reports
• Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 158 reports
• Hypersensitivity: 3,662 reports
• Hyperthyroidism (over activity of the thyroid gland): 149 reports
• Hypoacusis (loss of hearing): 225 reports
• Hypoaesthesia (reduced sense of touch or sensation): 2,345 reports
• Hypoaesthesia oral (reduced sense of touch or sensation in mouth): 300 reports
• Hypocalcaemia (levels of calcium in blood serum are abnormally low): 123 reports
• Hypoglycemia (low blood sugar): 239 reports
• Hypokalemia (low potassium): 536 reports
• Hypokinesia (decreased bodily movement): 214 reports
• Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 217 reports
• Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 406 reports
• Hypophagia (reduced food intake): 341 reports
• Hypotension (abnormally low blood pressure): 3,831 reports
• Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 379 reports
• Idiopathic pulmonary fibrosis (chronic lung disease): 260 reports
• Ill-defined disorder: 486 reports
• Immune system disorder: 144 reports
• Immunodeficiency: 219 reports
• Impaired gastric emptying: 151 reports
• Impaired healing: 551 reports
• Impaired work ability: 123 reports
• Incontinence (lack of moderation or self-control): 155 reports
• Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone): 146 reports
• Indigestion: 1,154 reports
• Infection: 1,649 reports
• Inflammation: 765 reports
• Influenza like illness: 1,073 reports
• Infusion related reaction: 5,080 reports
• Infusion site erythema (reddening of the skin at infusion site): 190 reports
• Infusion site extravasation (flow of (blood or lymph) from infusion site): 190 reports
• Infusion site pain: 283 reports
• Infusion site pruritus (severe itching at infusion site): 108 reports
• Infusion site swelling: 168 reports
• Initial insomnia (feeling of inadequate or poor-quality sleep): 113 reports
• Injection site bruising: 276 reports
• Injection site erythema (redness at injection site): 644 reports
• Injection site extravasation (flow of (blood or lymph) from injection site): 131 reports
• Injection site haemorrhage (bleeding from injection site): 210 reports
• Injection site pain: 1,033 reports
• Injection site pruritus (severe itching at injection site): 536 reports
• Injection site rash: 176 reports
• Injection site reaction: 457 reports
• Injection site swelling: 449 reports
• Injection site urticaria (rash of round, red welts on the skin at injection site): 217 reports
• Injection site warmth: 119 reports
• Injury: 1,051 reports
• Insomnia (sleeplessness): 3,487 reports
• Intentional overdose: 117 reports
• International normalised ratio increased: 198 reports
• Interstitial lung disease: 216 reports
• Interstitial nephritis (inflammation of the kidney): 210 reports
• Intervertebral disc degeneration (spinal disc degeneration): 341 reports
• Intervertebral disc disorder (spinal disc disorder): 113 reports
• Intervertebral disc protrusion (spinal disc protrusion): 484 reports
• Intestinal obstruction: 344 reports
• Iron deficiency: 111 reports
• Iron deficiency anaemia: 103 reports
• Irritability: 468 reports
• Irritable bowel syndrome: 235 reports
• Itching: 6,699 reports
• Jaundice - yellow skin (a yellowish pigmentation of the skin): 159 reports
• Jaw disorder (jaw disease): 132 reports
• Joint effusion (presence of extra fluid in joint covering): 195 reports
• Joint injury: 318 reports
• Joint pain: 5,282 reports
• Joint range of motion decreased (disease of joint movement): 164 reports
• Joint stiffness: 415 reports
• Joint swelling: 1,544 reports
• Kidney infection: 294 reports
• Kidney stones: 619 reports
• Knee joint replacement: 118 reports
• Lacrimation increased: 371 reports
• Laryngitis (inflammation of the larynx): 150 reports
• Leukocytosis (increased white blood cells): 226 reports
• Leukopenia (less number of white blood cells in blood): 471 reports
• Limb discomfort (discomfort in leg): 317 reports
• Limb injury: 330 reports
• Lip swelling: 696 reports
• Liver disorder (liver diseases): 136 reports
• Localised infection (infection at the single location): 291 reports
• Local swelling (swelling at the site of some application of substance or injury): 218 reports
• Loose tooth: 175 reports
• Loss of consciousness: 1,397 reports
• Lower limb fracture: 120 reports
• Lower respiratory tract infection: 467 reports
• Low tissue oxygen: 459 reports
• Lung disorder (lung disease): 408 reports
• Lung infection: 198 reports
• Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 258 reports
• Lung neoplasm (tumour of lung): 168 reports
• Lung neoplasm malignant (cancer tumour of lung): 158 reports
• Lymphadenitis (inflammation or enlargement of a lymph node): 107 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 642 reports
• Lymphocyte count decreased: 736 reports
• Lymphocyte percentage decreased: 118 reports
• Lymphoedema (localized fluid retention and tissue swelling): 117 reports
• Lymphoma (cancer that begins in immune system cells): 102 reports
• Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 103 reports
• Malaise (a feeling of general discomfort or uneasiness): 4,237 reports
• Malignant neoplasm progression (cancer tumour came back): 436 reports
• Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 172 reports
• Mania (a state of abnormally elevated or irritable mood): 136 reports
• Maternal exposure during pregnancy (use of substance during pregnancy): 347 reports
• Mean cell haemoglobin decreased (less than normal haemoglobin per red blood cell in a sample of blood): 114 reports
• Melaena (the passage of black, tarry stools): 107 reports
• Memory loss: 1,712 reports
• Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed): 111 reports
• Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 364 reports
• Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 188 reports
• Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 409 reports
• Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 128 reports
• Metastases to bone (cancer spreads to bone): 320 reports
• Metastases to central nervous system (cancer spreads to central nervous system): 134 reports
• Metastases to liver (cancer spreads to liver): 177 reports
• Metastases to lung (cancer spreads to lung): 196 reports
• Metastases to spine (cancer spreads to spine): 101 reports
• Micturition urgency (urgency to pass the urine): 174 reports
• Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night): 252 reports
• Migraine (headache): 1,504 reports
• Mitral valve incompetence (inefficient heart valve): 280 reports
• Mobility decreased (ability to move is reduced): 784 reports
• Monocyte count increased: 101 reports
• Mood swings (an extreme or rapid change in mood): 446 reports
• Mouth ulcers: 308 reports
• Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 274 reports
• Movement - uncontrolled or slow: 170 reports
• Movement - uncoordinated: 212 reports
• Mucosal inflammation (infection of mucous membrane): 383 reports
• Multi-organ failure (multisystem organ failure): 241 reports
• Multiple allergies (allergy to multiple agents): 169 reports
• Multiple myeloma (cancer of the plasma cells): 252 reports
• Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 384 reports
• Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 697 reports
• Muscle aches (muscle pain): 1,545 reports
• Muscle spasms (muscle contraction): 1,855 reports
• Muscle strain (an injury to a muscle in which the muscle fibres tear): 159 reports
• Muscle tightness: 267 reports
• Muscle twitching: 340 reports
• Musculoskeletal chest pain (pain in chest muscle or nerve or bones): 305 reports
• Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 232 reports
• Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 225 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 876 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1,246 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1,054 reports
• Nasopharyngitis (inflammation of the nasopharynx): 2,886 reports
• Nausea (feeling of having an urge to vomit): 9,396 reports
• Nausea and vomiting: 5,278 reports
• Neck pain: 985 reports
• Neoplasm malignant (cancer tumour): 371 reports
• Neoplasm progression (growth of tumour): 143 reports
• Nephrogenic anaemia (anaemia due to kidney disease): 318 reports
• Nerve injury: 130 reports
• Nervousness: 671 reports
• Nervous system disorder (a general class of medical conditions affecting the nervous system): 180 reports
• Neuralgia (pain in one or more nerves): 513 reports
• Neuropathy peripheral (surface nerve damage): 1,130 reports
• Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 470 reports
• Neutrophil count increased (excess than normal number of neutrophil a type of blood cell): 224 reports
• Nightmares (unpleasant dreams): 220 reports
• Night sweats (sweating in night): 409 reports
• Nodule (a small rock or mineral cluster): 226 reports
• Nosebleed (bleeding from nose): 852 reports
• Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 126 reports
• Obstructive airways disorder (a progressive disease that makes it hard to breathe): 150 reports
• Ocular hyperaemia (an abnormally large amount of blood in eye): 352 reports
• Oedema (fluid collection in tissue): 682 reports
• Oedema peripheral (superficial swelling): 1,598 reports
• Oesophagitis (inflammation of oesophagus): 222 reports
• Optic neuritis (optic nerve inflammation): 105 reports
• Oral candidiasis (fungal infection of mouth): 209 reports
• Oral discomfort (pain or irritation in mouth): 135 reports
• Oral disorder (mouth disease): 143 reports
• Oral herpes (viral infection of mouth): 369 reports
• Oral infection: 113 reports
• Oral pain: 576 reports
• Oral pruritus (itching in mouth): 101 reports
• Oropharyngeal pain: 1,671 reports
• Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 184 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 761 reports
• Osteolysis (dissolution of bone): 132 reports
• Osteomyelitis (infection of bone): 487 reports
• Osteonecrosis of jaw (death of bone of jaw): 691 reports
• Osteopenia (a condition where bone mineral density is lower than normal): 421 reports
• Osteoporosis (bones weak and more likely to break): 710 reports
• Otitis (ear infection): 372 reports
• Ovarian cysts (fluid filled sacs of the ovary): 195 reports
• Overdose: 790 reports
• Oxygen saturation decreased: 2,317 reports
• Pain: 6,908 reports
• Pain in extremity: 3,455 reports
• Pain in jaw: 713 reports
• Pain of skin: 232 reports
• Paleness (unusual lightness of skin colour): 472 reports
• Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome): 120 reports
• Pancreatitis (inflammation of pancreas): 341 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 504 reports
• Panic disorder: 448 reports
• Panniculitis (inflammation of the subcutaneous fat): 241 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2,239 reports
• Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect): 325 reports
• Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 153 reports
• Paroxysmal supraventricular tachycardia: 157 reports
• Pathological fracture (broken bone caused by disease): 146 reports
• Pelvic pain: 135 reports
• Pericardial effusion (fluid around the heart): 264 reports
• Pericarditis (inflammation of the pericardium): 137 reports
• Periodontitis (inflammation of the tissue around the teeth): 163 reports
• Peripheral coldness: 161 reports
• Peripheral swelling: 2,003 reports
• Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 418 reports
• Pharyngitis (inflammation of the pharynx, causing a sore throat): 280 reports
• Pharyngolaryngeal pain: 107 reports
• Photophobia (extreme sensitivity to light): 195 reports
• Photosensitivity reaction: 218 reports
• Physical disability: 116 reports
• Platelet count increased: 194 reports
• Pleural effusion (water on the lungs): 927 reports
• Pneumonia: 3,277 reports
• Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 147 reports
• Pneumonia viral: 197 reports
• Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 164 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 453 reports
• Poor quality sleep: 241 reports
• Poor venous access: 391 reports
• Post procedural complication: 156 reports
• Post procedural infection: 113 reports
• Post-traumatic stress disorder: 132 reports
• Pre-existing condition improved: 132 reports
• Pressure ulcer: 146 reports
• Presyncope: 223 reports
• Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 162 reports
• Procedural pain: 165 reports
• Proctalgia (pain in the rectum): 102 reports
• Productive cough: 866 reports
• Protein - urine: 177 reports
• Protein urine present: 168 reports
• Pruritus generalised (generalized itching): 494 reports
• Psoriasis (immune-mediated disease that affects the skin): 404 reports
• Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 454 reports
• Psychological trauma: 205 reports
• Psychomotor hyperactivity (feelings of extreme restlessness): 172 reports
• Psychotic disorder: 320 reports
• Pulmonary congestion (congestion in the lungs): 210 reports
• Pulmonary embolism (blockage of the main artery of the lung): 833 reports
• Pulmonary hypertension (increase in blood pressure in the lung artery): 221 reports
• Pulmonary mass: 195 reports
• Pulmonary oedema (fluid accumulation in the lungs): 517 reports
• Pulse absent: 103 reports
• Purulent discharge (discharge that contains pus): 152 reports
• Quality of life decreased: 146 reports
• Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 110 reports
• Rales (an abnormal respiratory sound characterized by fine crackles): 132 reports
• Rash erythematous (redness of the skin): 840 reports
• Rashes (redness): 8,746 reports
• Rash macular (small, flat red spots): 459 reports
• Rash maculo-papular (red area on the skin that is covered with small confluent bumps): 225 reports
• Rash papular (redness with papule): 272 reports
• Rash pruritic (redness with itching): 1,157 reports
• Rectal haemorrhage (bleeding from anus): 410 reports
• Red blood cell count decreased: 550 reports
• Red blood cell sedimentation rate increased: 325 reports
• Red blood cells urine positive: 180 reports
• Red cell distribution width increased: 314 reports
• Renal cyst (kidney cyst): 224 reports
• Renal disorder (kidney disease): 237 reports
• Renal failure acute (rapid kidney dysfunction): 484 reports
• Renal failure chronic (long lasting kidney dysfunction): 203 reports
• Renal impairment (severely reduced kidney function): 492 reports
• Renal injury (kidney injury): 547 reports
• Renal pain (kidney pain): 173 reports
• Renal tubular necrosis (death of kidney tubules): 153 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 544 reports
• Respiratory disorder (respiratory disease): 379 reports
• Respiratory distress (difficulty in breathing): 467 reports
• Respiratory rate increased (excess breathing rate/min): 409 reports
• Respiratory tract congestion (blockage on respiratory system): 210 reports
• Respiratory tract infection: 281 reports
• Restless leg syndrome (a powerful urge to move your legs): 327 reports
• Retching (strong involuntary effort to vomit): 271 reports
• Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 119 reports
• Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 1,559 reports
• Rheumatoid nodule (a local swelling or tissue lump with rheumatoid disease): 269 reports
• Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 236 reports
• Rib fracture: 353 reports
• Rickets (softening of bones): 150 reports
• Road traffic accident: 458 reports
• Rosacea (a skin condition that causes facial redness): 117 reports
• Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 195 reports
• Scab (a hard coating on the skin formed during the wound healing): 127 reports
• Scar: 282 reports
• Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 118 reports
• Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 197 reports
• Scoliosis (a medical condition in which a person's spine is curved from side to side): 174 reports
• Scratch: 293 reports
• Seasonal allergy (allergic condition due to certain season): 346 reports
• Secretion discharge: 109 reports
• Sedation: 262 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 532 reports
• Sensation of foreign body: 190 reports
• Sensory disturbance (sense disturbance): 197 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 1,067 reports
• Septic shock (shock due to blood infection): 222 reports
• Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum): 107 reports
• Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 115 reports
• Sinus bradycardia (an unusually slow heartbeat due to heart disease): 105 reports
• Sinus congestion (blockage of sinus): 368 reports
• Sinus disorder (disease of sinus): 449 reports
• Sinus headache (headache caused by sinus infections): 157 reports
• Sinusitis (inflammation of sinus): 2,071 reports
• Sinusitis - chronic: 157 reports
• Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 332 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 2,801 reports
• Skin burning sensation: 398 reports
• Skin cancer: 128 reports
• Skin - clammy: 228 reports
• Skin discoloration: 638 reports
• Skin discoloration - bluish (bluish colour of skin): 233 reports
• Skin disorder (skin disease): 397 reports
• Skin exfoliation (removal of the oldest dead skin cells): 525 reports
• Skin fissures (a crack in the skin): 175 reports
• Skin infection: 172 reports
• Skin irritation: 154 reports
• Skin necrosis (skin damage): 255 reports
• Skin reaction: 140 reports
• Skin ulcer: 580 reports
• Sleep apnea syndrome: 472 reports
• Sleep disorder: 739 reports
• Small intestinal obstruction (blockage in small intestine): 193 reports
• Sneezing: 350 reports
• Soft tissue disorder (disease of soft tissue): 199 reports
• Speech disorder: 531 reports
• Speech impairment (adult) (inability to speak (adult)): 692 reports
• Spinal column stenosis (narrowing of spinal column): 133 reports
• Spinal compression fracture (fracture due to spinal compression on bone): 143 reports
• Spinal disorder (disease of spine a back bone): 122 reports
• Spinal fracture (fracture in one of vertebrae): 112 reports
• Spinal osteoarthritis (joint cartilage loss in spine): 412 reports
• Spinal pain (pain in spine): 109 reports
• Splenomegaly (enlargement of spleen): 203 reports
• Sputum discolored: 180 reports
• Stable angina (a constant chest pain): 198 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 442 reports
• Stomatitis (inflammation of mucous membrane of mouth): 818 reports
• Stress and anxiety: 4,863 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 764 reports
• Suicidal ideation: 653 reports
• Suicide attempt: 339 reports
• Surgery: 248 reports
• Swallowing difficulty: 1,399 reports
• Swallowing pain or burning: 111 reports
• Sweating increased (excess sweating): 111 reports
• Swelling: 1,576 reports
• Swelling face: 1,228 reports
• Swollen tongue (swelling of tongue): 672 reports
• Synovial cyst (cyst of joint filled with synovial fluid): 204 reports
• Synovitis (inflammation of the synovial membrane): 669 reports
• Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 231 reports
• Tachypnea: 149 reports
• Tardive dyskinesia (a disorder that involves involuntary movements): 155 reports
• Taste - impaired: 602 reports
• Temperature intolerance (inability to go in temperature): 220 reports
• Tenderness (pain or discomfort when an affected area is touched): 326 reports
• Tendonitis (a condition that causes pain and swelling of tendons): 463 reports
• Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon): 401 reports
• The flu (the flu is caused by an influenza virus): 1,372 reports
• Therapeutic response decreased (less preventive response): 534 reports
• Therapeutic response unexpected: 426 reports
• Thirst: 145 reports
• Throat irritation: 1,329 reports
• Throat tightness: 958 reports
• Thrombocytopenia (decrease of platelets in blood): 1,939 reports
• Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 158 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 596 reports
• Thyroid diseases: 146 reports
• Tinnitus (a ringing in the ears): 476 reports
• Tongue disorder (disease of tongue): 455 reports
• Tooth abscess (pus formation in tooth): 532 reports
• Toothaches (tooth pain): 368 reports
• Tooth disorder (tooth disease): 590 reports
• Tooth extraction: 291 reports
• Tooth fracture: 185 reports
• Tooth loss: 153 reports
• Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 270 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 2,073 reports
• Tricuspid valve incompetence (inefficient heart valve): 175 reports
• Trismus (reduced opening of the jaws): 137 reports
• Tumor: 377 reports
• Type 2 diabetes: 328 reports
• Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 286 reports
• Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button): 121 reports
• Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter): 104 reports
• Unresponsive to stimuli: 253 reports
• Upper-airway cough syndrome: 180 reports
• Upper limb fracture: 123 reports
• Upper respiratory tract infection: 682 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 460 reports
• Urinary retention (the inability to completely or partially empty the bladder): 357 reports
• Urinary sediment present: 133 reports
• Urinary tract infection: 2,583 reports
• Urination - excessive at night: 135 reports
• Urination - painful: 537 reports
• Urine abnormality: 436 reports
• Urine ketone body present: 166 reports
• Urine leukocyte esterase positive: 242 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 5,283 reports
• Uterine leiomyoma (uterine benign tumour derived from smooth muscle): 137 reports
• Uveitis (inflammation of the uvea): 142 reports
• Vaginal bleeding: 206 reports
• Vaginal infection: 127 reports
• Vasculitis (inflammation of a blood vessel or blood vessels): 225 reports
• Ventricular extrasystoles (premature cardiac contraction): 123 reports
• Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 160 reports
• Viral infection: 389 reports
• Viral upper respiratory tract infection: 119 reports
• Vision blurred: 1,325 reports
• Visual acuity reduced (reduced clearness of vision): 186 reports
• Visual impairment: 742 reports
• Vitamin d decreased: 116 reports
• Vitreous floaters (spots before the eyes): 162 reports
• Weakness: 5,153 reports
• Weight decreased: 3,647 reports
• Weight fluctuation: 189 reports
• Weight increased: 3,016 reports
• Weight loss: 254 reports
• Wheezing (a high-pitched whistling sound made while you breath): 864 reports
• White blood cell count decreased: 1,477 reports
• White blood cell count increased: 605 reports
• White blood cells urine positive: 244 reports
• Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 163 reports
• Wound: 313 reports
• Wound infection: 141 reports
• Wrist fracture: 117 reports

• Tonic clonic movements (1,314 reports)

All the drugs that are associated with Tonic clonic movements:

• Tonic clonic movements (502 drugs)

All the conditions that are associated with Tonic clonic movements:

• Tonic clonic movements (306 conditions)

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