Benadryl and Wasting - from FDA reports

Wasting is found among people who take Benadryl, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Ambien, and have High blood cholesterol. This study is created by eHealthMe based on reports of 51,573 people who have side effects when taking Benadryl from FDA, and is updated regularly.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.

Who is eHealthMe: we are a data analysis company who specializes in health care industry. Our original studies have been referenced on 500+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and EANO. On eHealthMe, you can research drugs and find Care Guides (see testimonials).

On Sep, 18, 2018

51,573 people reported to have side effects when taking Benadryl.
Among them, 46 people (0.09%) have Wasting

Number of reports submitted per year:

Could Benadryl cause Wasting?

Time on Benadryl when people have Wasting *:

Gender of people who have Wasting when taking Benadryl *:

  • female: 66.67 %
  • male: 33.33 %

Age of people who have Wasting when taking Benadryl *:

Top conditions involved for these people *:

  1. Osteoporosis (bones weak and more likely to break): 7 people, 15.22%
  2. High Blood Cholesterol: 7 people, 15.22%
  3. Behcet's Syndrome (involves inflammation of the blood vessels): 5 people, 10.87%
  4. Diabetes: 4 people, 8.70%
  5. High Blood Pressure: 4 people, 8.70%

Click here to view more results or personalize the results to your gender and age

Top co-used drugs for these people *:

  1. Ambien: 9 people, 19.57%
  2. Lasix: 8 people, 17.39%
  3. Aredia: 8 people, 17.39%
  4. Gabapentin: 8 people, 17.39%
  5. Nystatin: 8 people, 17.39%

Click here to view more results or personalize the results to your gender and age

Top other side effects for these people *:

  1. Weakness: 16 people, 34.78%
  2. Pain: 15 people, 32.61%
  3. Fever: 14 people, 30.43%
  4. Memory Loss: 14 people, 30.43%
  5. Fatigue (feeling of tiredness): 13 people, 28.26%

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

Are you new to Benadryl or have questions?

On eHealthMe, Care Guides are people who "have been there". Many of them have been living or working with a drug, a condition, or both for a long time and gained substantial experience. Follow a Care Guide below to get answers between doctor visits, and guidance in everyday life.

More Care Guides for: Benadryl, Wasting

Volunteer or get paid to help people with your care experience

Do you have Wasting while taking Benadryl?

Related studies


Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from Benadryl 55,788 users)


Wasting (disease causes muscle and fat tissue to ""waste"" away) has been reported by people with high blood cholesterol, multiple sclerosis, high blood pressure (latest reports from 9,592 Wasting patients).

Drugs that are associated with Wasting
Wasting (1,449 drugs)
Could your condition cause Wasting
Wasting (1,388 conditions)
Benadryl side effects
Browse all side effects of Benadryl
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Benadryl and have Wasting

Recent updates

General studies

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.