Biotin and Cystocele - a phase IV clinical study of FDA data


Cystocele is found among people who take Biotin, especially for people who are 60+ old, have been taking the drug for 1 - 2 years.

The phase IV clinical study analyzes which people take Biotin and have Cystocele. It is created by eHealthMe based on reports of 27,544 people who have side effects when taking Biotin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

27,544 people reported to have side effects when taking Biotin.
Among them, 7 people (0.03%) have Cystocele.

What is Biotin?

Biotin has active ingredients of biotin. It is often used in hair loss. eHealthMe is studying from 29,033 Biotin users for its effectiveness, alternative drugs and more.

What is Cystocele?

Cystocele (condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth) is found to be associated with 706 drugs and 327 conditions by eHealthMe.

Number of Biotin and Cystocele reports submitted per year:

Could Biotin cause Cystocele?

Time on Biotin when people have Cystocele *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Age of people who have Cystocele when taking Biotin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Biotin *:

  1. Hibiclens: 2 people, 28.57%
  2. Sulfamethoxazole And Trimethoprim: 2 people, 28.57%
  3. Hydrocodone Bitartrate And Acetaminophen: 2 people, 28.57%
  4. Imitrex: 2 people, 28.57%
  5. Jakafi: 2 people, 28.57%
  6. Lactobacillus: 2 people, 28.57%
  7. Flaxseed: 2 people, 28.57%
  8. Estring: 2 people, 28.57%
  9. Glucosamine: 2 people, 28.57%
  10. Gleevec: 2 people, 28.57%

Common side effects people have besides Cystocele *:

  1. Rectocele (a bulging of the front wall of the rectum into the back wall of the vagina): 3 people, 42.86%
  2. Constipation: 3 people, 42.86%
  3. Atrophic Vulvovaginitis (inflammation of the vulva): 3 people, 42.86%
  4. Uterine Prolapse: 3 people, 42.86%
  5. Pain In Extremity: 2 people, 28.57%
  6. Fungal Infection: 2 people, 28.57%
  7. Lumbar Spinal Stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 2 people, 28.57%
  8. Menopausal Symptoms: 2 people, 28.57%
  9. Stress Urinary Incontinence (leak urine with things like coughing, sneezing or exercise): 2 people, 28.57%
  10. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 28.57%

Common conditions people have *:

  1. Pain: 3 people, 42.86%
  2. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 28.57%
  3. Muscle Spasms (muscle contraction): 2 people, 28.57%
  4. Back Pain: 2 people, 28.57%
  5. Constipation: 2 people, 28.57%
  6. Cough: 2 people, 28.57%
  7. Hypersensitivity: 2 people, 28.57%
  8. Interstitial Lung Disease: 2 people, 28.57%
  9. Joint Pain: 2 people, 28.57%
  10. Lung Disorder (lung disease): 2 people, 28.57%

* Approximation only. Some reports may have incomplete information.

Do you take Biotin and have Cystocele?

Check whether Cystocele is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Cystocele and when was it recovered:

Expand to all the drugs that have ingredients of biotin:

Alternative drugs to, pros and cons of Biotin:

Common Biotin side effects:

Browse all side effects of Biotin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Cystocele treatments and more:

COVID vaccines that are related to Cystocele:

Common drugs associated with Cystocele:

All the drugs that are associated with Cystocele:

Common conditions associated with Cystocele:

All the conditions that are associated with Cystocele:

How the study uses the data?

The study uses data from the FDA. It is based on biotin (the active ingredients of Biotin) and Biotin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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