Black cohosh and Otitis - a phase IV clinical study of FDA data


Otitis is reported only by a few people who take Black Cohosh.

The phase IV clinical study analyzes which people take Black cohosh and have Otitis. It is created by eHealthMe based on reports of 1,061 people who have side effects while taking Black cohosh from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 30, 2023

1,061 people reported to have side effects when taking Black cohosh.
Among them, 4 people (0.38%) have Otitis.

What is Black cohosh?

Black cohosh has active ingredients of black cohosh. It is often used in menopause. eHealthMe is studying from 1,212 Black cohosh users for its effectiveness, alternative drugs and more.

What is Otitis?

Otitis (ear infection) is found to be associated with 2,476 drugs and 1,700 conditions by eHealthMe.

Number of Black cohosh and Otitis reports submitted per year:

Could Black cohosh cause Otitis?

Gender of people who have Otitis when taking Black cohosh *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Otitis when taking Black cohosh *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 33.33 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 66.67 %

Common drugs people take besides Black cohosh *:

  1. Zyprexa: 3 people, 75.00%
  2. Serax: 3 people, 75.00%
  3. Dovonex: 3 people, 75.00%
  4. Clozaril: 3 people, 75.00%
  5. Lipitor: 3 people, 75.00%
  6. Celebrex: 3 people, 75.00%
  7. Cogentin: 3 people, 75.00%
  8. Rabeprazole Sodium: 2 people, 50.00%
  9. Penlac: 2 people, 50.00%
  10. Tylenol: 2 people, 50.00%

Common side effects people have besides Otitis *:

  1. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 3 people, 75.00%
  2. Hallucination, Auditory (perceiving sounds without auditory stimulus): 3 people, 75.00%
  3. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 3 people, 75.00%
  4. Salivary Hypersecretion (excess saliva secretion): 3 people, 75.00%
  5. Monocyte Count Decreased: 2 people, 50.00%
  6. The Flu (the flu is caused by an influenza virus): 2 people, 50.00%
  7. Fear: 2 people, 50.00%
  8. Eosinophil Count Abnormal: 2 people, 50.00%
  9. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 50.00%
  10. Eosinophil Count Increased: 1 person, 25.00%

Common conditions people have *:

  1. High Blood Cholesterol: 3 people, 75.00%
  2. Dyslipidaemia (abnormal amount of lipids): 3 people, 75.00%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 50.00%
  4. Rashes (redness): 2 people, 50.00%
  5. Nail Disorder (disease of nail): 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Black cohosh and have Otitis?

Check whether Otitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Otitis and when was it recovered:

Expand to all the drugs that have ingredients of black cohosh:

Alternative drugs to, pros and cons of Black cohosh:

Common Black cohosh side effects:

Browse all side effects of Black cohosh:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Otitis treatments and more:

COVID vaccines that are related to Otitis:

Common drugs associated with Otitis:

All the drugs that are associated with Otitis:

Common conditions associated with Otitis:

All the conditions that are associated with Otitis:

How the study uses the data?

The study uses data from the FDA. It is based on black cohosh (the active ingredients of Black cohosh) and Black cohosh (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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