Boniva and Infusion site reaction - a phase IV clinical study of FDA data


Infusion site reaction is reported only by a few people who take Boniva.

The phase IV clinical study analyzes which people take Boniva and have Infusion site reaction. It is created by eHealthMe based on reports of 26,821 people who have side effects while taking Boniva from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 21, 2023

26,821 people reported to have side effects when taking Boniva.
Among them, 3 people (0.01%) have Infusion site reaction.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,210 Boniva users for its effectiveness, alternative drugs and more.

What is Infusion site reaction?

Infusion site reaction is found to be associated with 725 drugs and 270 conditions by eHealthMe.

Number of Boniva and Infusion site reaction reports submitted per year:

Could Boniva cause Infusion site reaction?

Time on Boniva when people have Infusion site reaction *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Infusion site reaction when taking Boniva *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Infusion site reaction when taking Boniva *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 50 %
  • 50-59: 50 %
  • 60+: 0.0 %

Common drugs people take besides Boniva *:

  1. Ibandronate Sodium: 1 person, 33.33%
  2. Actonel: 1 person, 33.33%

Common side effects people have besides Infusion site reaction *:

  1. Swelling: 1 person, 33.33%
  2. Pain In Extremity: 1 person, 33.33%
  3. Pain: 1 person, 33.33%
  4. Oedema (fluid collection in tissue): 1 person, 33.33%
  5. Nerve Compression: 1 person, 33.33%
  6. Muscle Injury: 1 person, 33.33%
  7. Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 1 person, 33.33%
  8. Injection Site Extravasation (flow of (blood or lymph) from injection site): 1 person, 33.33%
  9. Infusion Site Pain: 1 person, 33.33%
  10. Hypoaesthesia (reduced sense of touch or sensation): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Boniva and have Infusion site reaction?

Check whether Infusion site reaction is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Infusion site reaction and when was it recovered:

Expand to all the drugs that have ingredients of ibandronate sodium:

Alternative drugs to, pros and cons of Boniva:

Common Boniva side effects:

Browse all side effects of Boniva:

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Infusion site reaction treatments and more:

COVID vaccines that are related to Infusion site reaction:

Common drugs associated with Infusion site reaction:

All the drugs that are associated with Infusion site reaction:

Common conditions associated with Infusion site reaction:

All the conditions that are associated with Infusion site reaction:

How the study uses the data?

The study uses data from the FDA. It is based on ibandronate sodium (the active ingredients of Boniva) and Boniva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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