Breo ellipta and Acne aggravated - a phase IV clinical study of FDA data


Acne aggravated is found among people who take Breo ellipta, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Breo ellipta and have Acne aggravated. It is created by eHealthMe based on reports of 30,432 people who have side effects when taking Breo ellipta from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 15, 2023

30,432 people reported to have side effects when taking Breo ellipta.
Among them, 32 people (0.11%) have Acne aggravated.

What is Breo ellipta?

Breo ellipta has active ingredients of fluticasone furoate; vilanterol trifenatate. It is often used in asthma. eHealthMe is studying from 30,687 Breo ellipta users for its effectiveness, alternative drugs and more.

What is Acne aggravated?

Acne aggravated (acne aggravated-a skin disease) is found to be associated with 1,293 drugs and 455 conditions by eHealthMe.

Number of Breo ellipta and Acne aggravated reports submitted per year:

Could Breo ellipta cause Acne aggravated?

Time on Breo ellipta when people have Acne aggravated *:

  • < 1 month: 66.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Acne aggravated when taking Breo ellipta *:

  • female: 56.25 %
  • male: 43.75 %

Age of people who have Acne aggravated when taking Breo ellipta *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 40.91 %
  • 60+: 59.09 %

Common drugs people take besides Breo ellipta *:

  1. Singulair: 10 people, 31.25%
  2. Spiriva: 10 people, 31.25%
  3. Qvar: 9 people, 28.12%
  4. Symbicort: 8 people, 25.00%
  5. Kadian: 7 people, 21.88%
  6. Oxycodone: 5 people, 15.62%
  7. Xolair: 5 people, 15.62%
  8. Claritin: 4 people, 12.50%
  9. Morphine: 4 people, 12.50%
  10. Dupixent: 4 people, 12.50%

Common side effects people have besides Acne aggravated *:

  1. Joint Pain: 12 people, 37.50%
  2. Fatigue (feeling of tiredness): 12 people, 37.50%
  3. Abdominal Pain: 11 people, 34.38%
  4. Pain In Extremity: 11 people, 34.38%
  5. Oropharyngeal Pain: 11 people, 34.38%
  6. Facial Pain: 11 people, 34.38%
  7. Hypoaesthesia (reduced sense of touch or sensation): 11 people, 34.38%
  8. Pain: 11 people, 34.38%
  9. Weakness: 11 people, 34.38%
  10. Blood Urine Present: 10 people, 31.25%

Common conditions people have *:

  1. Herpes Zoster: 7 people, 21.88%
  2. Headache (pain in head): 7 people, 21.88%
  3. Eye Pain: 7 people, 21.88%
  4. Pneumonia: 6 people, 18.75%
  5. Facial Pain: 6 people, 18.75%
  6. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 9.38%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.25%
  8. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 6.25%
  9. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 3.12%
  10. Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Breo ellipta and have Acne aggravated?

Check whether Acne aggravated is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Acne aggravated and when was it recovered:

Expand to all the drugs that have ingredients of fluticasone furoate; vilanterol trifenatate:

Alternative drugs to, pros and cons of Breo ellipta:

Common Breo ellipta side effects:

Browse all side effects of Breo ellipta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Acne aggravated treatments and more:

COVID vaccines that are related to Acne aggravated:

Common drugs associated with Acne aggravated:

All the drugs that are associated with Acne aggravated:

Common conditions associated with Acne aggravated:

All the conditions that are associated with Acne aggravated:

How the study uses the data?

The study uses data from the FDA. It is based on fluticasone furoate; vilanterol trifenatate (the active ingredients of Breo ellipta) and Breo ellipta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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