Calcium citrate and Ototoxicity - a phase IV clinical study of FDA data


Ototoxicity is reported only by a few people who take Calcium Citrate.

The phase IV clinical study analyzes which people take Calcium citrate and have Ototoxicity. It is created by eHealthMe based on reports of 9,516 people who have side effects while taking Calcium citrate from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 19, 2022

9,516 people reported to have side effects when taking Calcium citrate.
Among them, 3 people (0.03%) have Ototoxicity.

What is Calcium citrate?

Calcium citrate has active ingredients of calcium. It is often used in osteopenia. eHealthMe is studying from 8,704 Calcium citrate users for its effectiveness, alternative drugs and more.

What is Ototoxicity?

Ototoxicity (damage to the ear) is found to be associated with 599 drugs and 337 conditions by eHealthMe.

Number of Calcium citrate and Ototoxicity reports submitted per year:

Could Calcium citrate cause Ototoxicity?

Gender of people who have Ototoxicity when taking Calcium citrate *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Ototoxicity when taking Calcium citrate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Calcium citrate *:

  1. Xanax: 3 people, 100.00%
  2. Vitamin C: 3 people, 100.00%
  3. Coenzyme Q10: 3 people, 100.00%
  4. Deltasone: 3 people, 100.00%
  5. Desyrel: 3 people, 100.00%
  6. Duragesic: 3 people, 100.00%
  7. Elelyso: 3 people, 100.00%
  8. Lidoderm: 3 people, 100.00%
  9. Lyrica: 3 people, 100.00%
  10. Paroex: 3 people, 100.00%

Common side effects people have besides Ototoxicity *:

  1. Troponin Increased: 3 people, 100.00%
  2. Stress And Anxiety: 3 people, 100.00%
  3. Staphylococcal Bacteraemia (a bacterial infection of blood): 3 people, 100.00%
  4. Pain: 3 people, 100.00%
  5. Encephalopathy (functioning of the brain is affected by some agent or condition): 3 people, 100.00%
  6. Diarrhea: 3 people, 100.00%
  7. Prostate Cancer Metastatic: 2 people, 66.67%

Common conditions people have *:

  1. Stress And Anxiety: 3 people, 100.00%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 100.00%
  3. Prostate Cancer Metastatic: 3 people, 100.00%
  4. Prostate Cancer: 3 people, 100.00%
  5. Pain: 3 people, 100.00%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 100.00%
  7. High Blood Cholesterol: 3 people, 100.00%
  8. Heart Disease: 3 people, 100.00%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 100.00%
  10. Diarrhea: 3 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Calcium citrate and have Ototoxicity?

Check whether Ototoxicity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Ototoxicity and when was it recovered:

Expand to all the drugs that have ingredients of calcium:

Alternative drugs to, pros and cons of Calcium citrate:

Common Calcium citrate side effects:

Browse all side effects of Calcium citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Ototoxicity treatments and more:

COVID vaccines that are related to Ototoxicity:

Common drugs associated with Ototoxicity:

All the drugs that are associated with Ototoxicity:

All the conditions that are associated with Ototoxicity:

How the study uses the data?

The study uses data from the FDA. It is based on calcium (the active ingredients of Calcium citrate) and Calcium citrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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