Capecitabine and Acute prerenal failure - a phase IV clinical study of FDA data
We study 55,169 people who have side effects when taking Capecitabine. Acute prerenal failure is found, especially among people who are male, 60+ old, have been taking the drug for < 1 month, also take Oxaliplatin and have Gastric cancer.
The phase IV clinical study analyzes which people take Capecitabine and have Acute prerenal failure. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
55,169 people reported to have side effects when taking Capecitabine.
Among them, 24 people (0.04%) have Acute prerenal failure.
What is Capecitabine?
Capecitabine has active ingredients of capecitabine. Currently, eHealthMe is studying from 55,211 Capecitabine users.
What is Acute prerenal failure?
Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney) is found to be associated with 894 drugs and 592 conditions by eHealthMe. Currently, we are studying 1,782 people who have Acute prerenal failure.
Number of Capecitabine and Acute prerenal failure reports submitted per year:
Time on Capecitabine when people have Acute prerenal failure *:
- < 1 month: 78.57 %
- 1 - 6 months: 21.43 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Acute prerenal failure when taking Capecitabine *:
- female: 17.39 %
- male: 82.61 %
Age of people who have Acute prerenal failure when taking Capecitabine *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 40.91 %
- 60+: 59.09 %
Common drugs people take besides Capecitabine *:
- Oxaliplatin: 13 people, 54.17%
- Lorazepam: 5 people, 20.83%
- Atrovent: 5 people, 20.83%
- Lasix: 4 people, 16.67%
- Nitroglycerin: 4 people, 16.67%
- Flonase: 4 people, 16.67%
- Cozaar: 4 people, 16.67%
- Cisplatin: 4 people, 16.67%
- Avandia: 4 people, 16.67%
- Omeprazole: 4 people, 16.67%
Common side effects people have besides Acute prerenal failure *:
- Diarrhea: 10 people, 41.67%
- Dehydration (dryness resulting from the removal of water): 9 people, 37.50%
- Nausea And Vomiting: 8 people, 33.33%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 20.83%
- Fever: 5 people, 20.83%
- Staphylococcal Sepsis (blood infection by an infection with staphylococcus bacteria): 4 people, 16.67%
- Enteritis (inflammation of the small intestine): 4 people, 16.67%
- Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 4 people, 16.67%
- Infection: 4 people, 16.67%
- Pancreatitis Acute (sudden inflammation of pancreas): 4 people, 16.67%
Common conditions people have *:
- Hepatic Neoplasm Malignant (liver cancer): 2 people, 8.33%
- Gastroesophageal Cancer: 2 people, 8.33%
- Gastric Cancer (stomach cancer): 2 people, 8.33%
- Nausea (feeling of having an urge to vomit): 1 person, 4.17%
- Metastatic Gastric Cancer (cancer types can spread to the stomach from other place): 1 person, 4.17%
- Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 1 person, 4.17%
- Colon Cancer Metastatic (cancer of colon spreads to other part of body): 1 person, 4.17%
* Approximation only. Some reports may have incomplete information.
Do you take Capecitabine and have Acute prerenal failure?Check whether Acute prerenal failure is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Pinto HP, Bhat RM, Shet D, Dandekeri S, "Compound mucocutaneous adverse effects of oral capecitabine in a patient", Indian dermatology online journal, 2014 Jan .
- Kang SM, Baek JY, Hwangbo B, Kim HY, Lee GK, Lee HS, "A case of capecitabine-induced sarcoidosis", Tuberculosis and respiratory diseases, 2012 Mar .
Capecitabine side effects by duration, gender and age:
- Capecitabine side effects (55,211 reports)
Acute prerenal failure treatments and more:
- Acute prerenal failure (1,782 reports)
Common drugs associated with Acute prerenal failure:
- Aspirin: 241 reports
- Lasix: 182 reports
- Furosemide: 161 reports
- Metformin: 148 reports
- Lisinopril: 123 reports
- Prednisone: 111 reports
- Digoxin: 106 reports
All the drugs that are associated with Acute prerenal failure:
- Acute prerenal failure (894 drugs)
Common conditions associated with Acute prerenal failure:
- High blood pressure: 256 reports
All the conditions that are associated with Acute prerenal failure:
- Acute prerenal failure (592 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on capecitabine (the active ingredients of Capecitabine) and Capecitabine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Naprosyn and Duopa drug interaction - 19 seconds ago
- Claritin and Aggression Aggravated - 26 seconds ago
- Niaspan and Gatifloxacin drug interaction - 32 seconds ago
- Levaquin and Hepatomegaly - 42 seconds ago
- Entresto and Meloxicam drug interaction - 44 seconds ago
- Montelukast Sodium and Fluoxetine drug interaction - a minute ago
- Miralax and Minoxidil drug interaction - a minute ago
- Amlodipine and Loniten drug interaction - a minute ago
- Insulin and Orgaran drug interaction - a minute ago
- Advair Hfa and Dry Eyes - a minute ago