Capoten and Chills - a phase IV clinical study of FDA data


We study 2,920 people who have side effects when taking Capoten. Chills is found, especially among people who are male, 60+ old, also take Lasix and have Acute coronary syndrome.

The phase IV clinical study analyzes which people take Capoten and have Chills. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 01, 2023

2,920 people reported to have side effects when taking Capoten.
Among them, 24 people (0.82%) have Chills.

What is Capoten?

Capoten has active ingredients of captopril. It is used in high blood pressure. Currently, eHealthMe is studying from 2,943 Capoten users.

What is Chills?

Chills (felling of cold) is found to be associated with 3,763 drugs and 3,418 conditions by eHealthMe. Currently, we are studying 137,586 people who have Chills.

Number of Capoten and Chills reports submitted per year:

Could Capoten cause Chills?

Gender of people who have Chills when taking Capoten *:

  • female: 43.48 %
  • male: 56.52 %

Age of people who have Chills when taking Capoten *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5.56 %
  • 40-49: 11.11 %
  • 50-59: 11.11 %
  • 60+: 72.22 %

Common drugs people take besides Capoten *:

  1. Lasix: 8 people, 33.33%
  2. Digoxin: 6 people, 25.00%
  3. Lanoxin: 6 people, 25.00%
  4. Prilosec: 5 people, 20.83%
  5. Prednisone: 4 people, 16.67%
  6. Lopressor: 4 people, 16.67%
  7. Furadantin: 3 people, 12.50%
  8. Prozac: 3 people, 12.50%
  9. Baclofen: 3 people, 12.50%
  10. Pravachol: 3 people, 12.50%

Common side effects people have besides Chills *:

  1. Weakness: 7 people, 29.17%
  2. Nausea (feeling of having an urge to vomit): 7 people, 29.17%
  3. Fever: 6 people, 25.00%
  4. Cardiac Failure Congestive: 5 people, 20.83%
  5. Dehydration (dryness resulting from the removal of water): 5 people, 20.83%
  6. Breathing Difficulty: 5 people, 20.83%
  7. Chest Pain: 5 people, 20.83%
  8. Hyperglycemia (high blood sugar): 4 people, 16.67%
  9. Fatigue (feeling of tiredness): 4 people, 16.67%
  10. Hypotension (abnormally low blood pressure): 4 people, 16.67%

Common conditions people have *:

  1. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 1 person, 4.17%
  2. Type 2 Diabetes: 1 person, 4.17%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 4.17%
  4. Erection Problems: 1 person, 4.17%
  5. Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Capoten and have Chills?

Check whether Chills is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Capoten side effects by duration, gender and age:

Chills treatments and more:

Common drugs associated with Chills:

All the drugs that are associated with Chills:

Common conditions associated with Chills:

All the conditions that are associated with Chills:

How the study uses the data?

The study uses data from the FDA. It is based on captopril (the active ingredients of Capoten) and Capoten (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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