Carafate and Dupuytren's contracture - a phase IV clinical study of FDA data
Summary:
Dupuytren's contracture is reported only by a few people who take Carafate.
The phase IV clinical study analyzes which people take Carafate and have Dupuytren's contracture. It is created by eHealthMe based on reports of 12,465 people who have side effects while taking Carafate from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
12,465 people reported to have side effects when taking Carafate.
Among them, 5 people (0.04%) have Dupuytren's contracture.
What is Carafate?
Carafate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 12,196 Carafate users for its effectiveness, alternative drugs and more.
What is Dupuytren's contracture?
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 445 drugs and 208 conditions by eHealthMe.
Number of Carafate and Dupuytren's contracture reports submitted per year:

Gender of people who have Dupuytren's contracture when taking Carafate *:
- female: 100 %
- male: 0.0 %
Age of people who have Dupuytren's contracture when taking Carafate *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 100 %
Common drugs people take besides Carafate *:
- Zofran: 2 people, 40.00%
- Norvasc: 2 people, 40.00%
- Amlodipine: 2 people, 40.00%
- Bentyl: 2 people, 40.00%
- Humira: 2 people, 40.00%
- Hydrocodone: 2 people, 40.00%
- Xanax: 2 people, 40.00%
- Actonel: 2 people, 40.00%
- Potassium: 2 people, 40.00%
- Ventolin Hfa: 2 people, 40.00%
Common side effects people have besides Dupuytren's contracture *:
- Pain In Extremity: 3 people, 60.00%
- Depression: 3 people, 60.00%
- Weight Decreased: 2 people, 40.00%
- Aptyalism (deficiency or absence of saliva): 2 people, 40.00%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 40.00%
- Asthma: 2 people, 40.00%
- Bone Disorder: 2 people, 40.00%
- Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 2 people, 40.00%
- Cough: 2 people, 40.00%
- Dry Mouth: 2 people, 40.00%
Common conditions people have *:
- Neck Pain: 2 people, 40.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 40.00%
- High Blood Pressure: 2 people, 40.00%
- Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 2 people, 40.00%
- Blood Potassium Decreased: 2 people, 40.00%
- Back Pain: 2 people, 40.00%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 40.00%
- Lung Cancer - Non-Small Cell (lung cancer): 1 person, 20.00%
- Asthma: 1 person, 20.00%
* Approximation only. Some reports may have incomplete information.
Do you take Carafate and have Dupuytren's contracture?
Check whether Dupuytren's contracture is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Dupuytren's contracture and when was it recovered:
Expand to all the drugs that have ingredients of sucralfate:
Alternative drugs to, pros and cons of Carafate:
- Carafate (12,196 reports)
Common Carafate side effects:
- Abdominal discomfort: 286 reports
- Abdominal distension: 210 reports
- Abdominal pain: 636 reports
- Abdominal pain upper: 557 reports
- Acute kidney failure: 438 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 148 reports
- Anaemia (lack of blood): 518 reports
- Anhedonia (inability to experience pleasure from activities usually found enjoyable): 125 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 335 reports
- Arrhythmias (irregular heartbeat): 154 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 163 reports
- Asthma: 187 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 195 reports
- Back pain: 497 reports
- Balance disorder: 106 reports
- Blood glucose increased: 154 reports
- Bone disorder: 150 reports
- Bone pain: 180 reports
- Breathing difficulty: 848 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 191 reports
- Burning sensation: 114 reports
- Cardiac arrest: 102 reports
- Cardiac disorder: 163 reports
- Cardiac failure congestive: 231 reports
- Cellulitis (infection under the skin): 190 reports
- Chest pain: 663 reports
- Chills (felling of cold): 199 reports
- Chronic kidney disease: 378 reports
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 145 reports
- Confusional state: 224 reports
- Constipation: 423 reports
- Cough: 363 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 103 reports
- Death: 372 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 101 reports
- Dehydration (dryness resulting from the removal of water): 426 reports
- Depression: 491 reports
- Diabetes: 107 reports
- Diarrhea: 964 reports
- Disease progression: 115 reports
- Dizziness: 623 reports
- Drowsiness: 245 reports
- Drug hypersensitivity: 201 reports
- Drug ineffective: 633 reports
- Dry mouth: 178 reports
- Emotional distress: 116 reports
- Fainting (loss of consciousness and postural tone): 181 reports
- Fall: 510 reports
- Fatigue (feeling of tiredness): 1,042 reports
- Fever: 508 reports
- Flatulence (flatus expelled through the anus): 120 reports
- Gait disturbance: 215 reports
- Gallstones (stone formation by bile component): 138 reports
- Gastric ulcer (stomach ulcer): 309 reports
- Gastritis (inflammation of stomach): 255 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 540 reports
- Gastrointestinal disorder (functional problems of gastrointestinal tract): 122 reports
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 418 reports
- Haematocrit decreased: 109 reports
- Haemoglobin decreased: 260 reports
- Haemorrhage (bleeding): 157 reports
- Haemorrhoids (a swollen vein or group of veins in the region of the anus): 101 reports
- Hair loss: 193 reports
- Headache (pain in head): 711 reports
- Head injury: 226 reports
- Heart attack: 205 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 196 reports
- Heart rate increased: 121 reports
- Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 173 reports
- High blood cholesterol: 158 reports
- High blood pressure: 510 reports
- Hospitalisation: 106 reports
- Hot flush (sudden feelings of heat): 105 reports
- Hyperhidrosis (abnormally increased sweating): 169 reports
- Hypersensitivity: 142 reports
- Hypoaesthesia (reduced sense of touch or sensation): 280 reports
- Hypokalemia (low potassium): 166 reports
- Hypotension (abnormally low blood pressure): 410 reports
- Indigestion: 312 reports
- Infection: 136 reports
- Injection site pain: 164 reports
- Injury: 254 reports
- Insomnia (sleeplessness): 371 reports
- Itching: 296 reports
- Joint pain: 510 reports
- Joint swelling: 105 reports
- Loss of consciousness: 157 reports
- Malaise (a feeling of general discomfort or uneasiness): 501 reports
- Memory loss: 266 reports
- Migraine (headache): 212 reports
- Muscle aches (muscle pain): 216 reports
- Muscle spasms (muscle contraction): 281 reports
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 119 reports
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 112 reports
- Nasopharyngitis (inflammation of the nasopharynx): 125 reports
- Nausea (feeling of having an urge to vomit): 1,208 reports
- Nausea and vomiting: 775 reports
- Neuropathy peripheral (surface nerve damage): 120 reports
- Nosebleed (bleeding from nose): 153 reports
- Oedema (fluid collection in tissue): 122 reports
- Oedema peripheral (superficial swelling): 285 reports
- Oesophagitis (inflammation of oesophagus): 163 reports
- Oropharyngeal pain: 143 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 174 reports
- Osteomyelitis (infection of bone): 104 reports
- Osteonecrosis of jaw (death of bone of jaw): 124 reports
- Osteopenia (a condition where bone mineral density is lower than normal): 120 reports
- Osteoporosis (bones weak and more likely to break): 129 reports
- Pain: 939 reports
- Pain in extremity: 447 reports
- Pain in jaw: 121 reports
- Pancreatitis (inflammation of pancreas): 131 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 113 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 218 reports
- Peripheral swelling: 121 reports
- Pleural effusion (water on the lungs): 175 reports
- Pneumonia: 548 reports
- Pulmonary embolism (blockage of the main artery of the lung): 137 reports
- Rashes (redness): 457 reports
- Rectal haemorrhage (bleeding from anus): 132 reports
- Renal failure acute (rapid kidney dysfunction): 141 reports
- Renal injury (kidney injury): 104 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 133 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 246 reports
- Sinusitis (inflammation of sinus): 278 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 109 reports
- Spinal osteoarthritis (joint cartilage loss in spine): 110 reports
- Stomatitis (inflammation of mucous membrane of mouth): 144 reports
- Stress and anxiety: 693 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 170 reports
- Swallowing difficulty: 303 reports
- Swelling: 132 reports
- The flu (the flu is caused by an influenza virus): 122 reports
- Thrombocytopenia (decrease of platelets in blood): 353 reports
- Thrombosis (formation of a blood clot inside a blood vessel): 129 reports
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 121 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 242 reports
- Upper respiratory tract infection: 139 reports
- Urinary tract infection: 349 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 116 reports
- Vision blurred: 145 reports
- Weakness: 743 reports
- Weight decreased: 584 reports
- Weight increased: 267 reports
- White blood cell count decreased: 161 reports
Browse all side effects of Carafate:
a b c d e f g h i j k l m n o p q r s t u v w x y zDupuytren's contracture treatments and more:
- Dupuytren's contracture (2,031 reports)
COVID vaccines that are related to Dupuytren's contracture:
- Dupuytren's contracture in Moderna COVID Vaccine
- Dupuytren's contracture in Pfizer BioNTech Covid Vaccine
- Dupuytren's contracture in Johnson and Johnson Covid Vaccine
Common drugs associated with Dupuytren's contracture:
- Xiaflex: 137 reports
All the drugs that are associated with Dupuytren's contracture:
- Dupuytren's contracture (445 drugs)
Common conditions associated with Dupuytren's contracture:
- Ra: 104 reports
All the conditions that are associated with Dupuytren's contracture:
- Dupuytren's contracture (208 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on sucralfate (the active ingredients of Carafate) and Carafate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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