Carboplatin and Cervical spinal stenosis - a phase IV clinical study of FDA data

Summary:

Cervical spinal stenosis is found among people who take Carboplatin, especially for people who are 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Carboplatin and have Cervical spinal stenosis. It is created by eHealthMe based on reports of 100,604 people who have side effects when taking Carboplatin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Sep, 29, 2022

100,604 people reported to have side effects when taking Carboplatin.
Among them, 83 people (0.08%) have Cervical spinal stenosis.


What is Carboplatin?

Carboplatin has active ingredients of carboplatin. It is often used in cancer. eHealthMe is studying from 100,859 Carboplatin users for its effectiveness, alternative drugs and more.

What is Cervical spinal stenosis?

Cervical spinal stenosis (narrowing of the spinal canal in the neck) is found to be associated with 951 drugs and 442 conditions by eHealthMe.

Number of Carboplatin and Cervical spinal stenosis reports submitted per year:

Could Carboplatin cause Cervical spinal stenosis?

Time on Carboplatin when people have Cervical spinal stenosis *:

  • < 1 month: 27.27 %
  • 1 - 6 months: 72.73 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Age of people who have Cervical spinal stenosis when taking Carboplatin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 15.58 %
  • 50-59: 40.26 %
  • 60+: 44.16 %

Common drugs people take besides Carboplatin *:

  1. Zometa: 80 people, 96.39%
  2. Aredia: 79 people, 95.18%
  3. Taxotere: 65 people, 78.31%
  4. Ms Contin: 51 people, 61.45%
  5. Dilaudid: 44 people, 53.01%
  6. Coumadin: 44 people, 53.01%
  7. Duragesic-100: 40 people, 48.19%
  8. Megace: 38 people, 45.78%
  9. Ativan: 36 people, 43.37%
  10. Levaquin: 35 people, 42.17%

Common side effects people have besides Cervical spinal stenosis *:

  1. Intervertebral Disc Protrusion (spinal disc protrusion): 76 people, 91.57%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 71 people, 85.54%
  3. Anaemia (lack of blood): 68 people, 81.93%
  4. Osteonecrosis Of Jaw (death of bone of jaw): 67 people, 80.72%
  5. Pain: 59 people, 71.08%
  6. Abdominal Pain: 59 people, 71.08%
  7. Neck Pain: 57 people, 68.67%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 57 people, 68.67%
  9. Nausea (feeling of having an urge to vomit): 56 people, 67.47%
  10. Bone Disorder: 56 people, 67.47%

Common conditions people have *:

  1. Breast Cancer: 31 people, 37.35%
  2. Breast Cancer Metastatic: 21 people, 25.30%
  3. Metastases To Bone (cancer spreads to bone): 21 people, 25.30%
  4. Ovarian Cancer (cancer of ovary): 20 people, 24.10%
  5. Hot Flush (sudden feelings of heat): 20 people, 24.10%
  6. Neoplasm Malignant (cancer tumour): 20 people, 24.10%
  7. Discomfort: 20 people, 24.10%
  8. Migraine (headache): 20 people, 24.10%
  9. Granulocyte Count Decreased: 19 people, 22.89%
  10. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 14 people, 16.87%

* Approximation only. Some reports may have incomplete information.

Do you take Carboplatin and have Cervical spinal stenosis?

Check whether Cervical spinal stenosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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Cervical spinal stenosis treatments and more:

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Common drugs associated with Cervical spinal stenosis:

All the drugs that are associated with Cervical spinal stenosis:

Common conditions associated with Cervical spinal stenosis:

All the conditions that are associated with Cervical spinal stenosis:

How the study uses the data?

The study uses data from the FDA. It is based on carboplatin (the active ingredients of Carboplatin) and Carboplatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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