Cardura and Ototoxicity - a phase IV clinical study of FDA data

• Cardura (19,604 reports)

• Abdominal distension: 135 reports
• Abdominal pain: 217 reports
• Abdominal pain upper: 255 reports
• Acute kidney failure: 373 reports
• Agitation (state of anxiety or nervous excitement): 128 reports
• Anaemia (lack of blood): 517 reports
• Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 115 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 214 reports
• Arrhythmias (irregular heartbeat): 204 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 361 reports
• Back pain: 370 reports
• Blood creatine phosphokinase increased: 109 reports
• Blood creatinine increased: 247 reports
• Blood glucose increased: 193 reports
• Blood urea increased: 139 reports
• Bone disorder: 107 reports
• Bone pain: 108 reports
• Bradycardia (abnormally slow heart action): 160 reports
• Breathing difficulty: 550 reports
• Cardiac arrest: 150 reports
• Cardiac disorder: 261 reports
• Cardiac failure: 139 reports
• Cardiac failure congestive: 369 reports
• Cataract (clouding of the lens inside the eye): 119 reports
• Cellulitis (infection under the skin): 144 reports
• Chest pain: 634 reports
• Chills (felling of cold): 156 reports
• Chronic kidney disease: 145 reports
• Confusion: 103 reports
• Confusional state: 185 reports
• Constipation: 402 reports
• Coronary heart disease (narrowing or blockage of the coronary arteries): 194 reports
• Cough: 344 reports
• Death: 363 reports
• Dehydration (dryness resulting from the removal of water): 255 reports
• Depression: 368 reports
• Diabetes: 258 reports
• Diarrhea: 665 reports
• Difficulty in micturition (difficulty to urinate): 127 reports
• Difficulty in walking: 113 reports
• Dizziness: 619 reports
• Drowsiness: 181 reports
• Drug effect decreased: 104 reports
• Drug hypersensitivity: 183 reports
• Drug ineffective: 1,146 reports
• Dry mouth: 220 reports
• Dyspnea exertional: 108 reports
• Emotional distress: 145 reports
• Enlarged prostate: 287 reports
• Erection problems: 219 reports
• Fainting (loss of consciousness and postural tone): 523 reports
• Fall: 660 reports
• Fatigue (feeling of tiredness): 816 reports
• Fever: 453 reports
• Flatulence (flatus expelled through the anus): 116 reports
• Gait disturbance: 160 reports
• Gallstones (stone formation by bile component): 145 reports
• Gastric ulcer (stomach ulcer): 168 reports
• Gastritis (inflammation of stomach): 135 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 142 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 189 reports
• Haematocrit decreased: 119 reports
• Haemoglobin decreased: 230 reports
• Haemorrhage (bleeding): 141 reports
• Hair loss: 124 reports
• Headache (pain in head): 414 reports
• Head injury: 207 reports
• Heart attack: 527 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 255 reports
• Heart rate increased: 130 reports
• High blood cholesterol: 334 reports
• High blood pressure: 783 reports
• Hyperhidrosis (abnormally increased sweating): 142 reports
• Hyperkalemia (damage to or disease of the kidney): 191 reports
• Hypersensitivity: 225 reports
• Hypertensive crisis: 120 reports
• Hypoaesthesia (reduced sense of touch or sensation): 207 reports
• Hypoglycemia (low blood sugar): 154 reports
• Hypokalemia (low potassium): 119 reports
• Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 153 reports
• Hypotension (abnormally low blood pressure): 889 reports
• Indigestion: 221 reports
• Infection: 150 reports
• Injury: 222 reports
• Insomnia (sleeplessness): 191 reports
• International normalised ratio increased: 102 reports
• Itching: 284 reports
• Joint pain: 430 reports
• Loss of consciousness: 312 reports
• Malaise (a feeling of general discomfort or uneasiness): 470 reports
• Memory loss: 194 reports
• Mitral valve incompetence (inefficient heart valve): 120 reports
• Muscle aches (muscle pain): 295 reports
• Muscle spasms (muscle contraction): 134 reports
• Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 107 reports
• Nasopharyngitis (inflammation of the nasopharynx): 104 reports
• Nausea (feeling of having an urge to vomit): 748 reports
• Nausea and vomiting: 322 reports
• Neuropathy peripheral (surface nerve damage): 101 reports
• Nosebleed (bleeding from nose): 157 reports
• Oedema (fluid collection in tissue): 206 reports
• Oedema lower limb (fluid collection in tissue of lower leg): 189 reports
• Oedema peripheral (superficial swelling): 447 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 128 reports
• Pain: 735 reports
• Pain in extremity: 296 reports
• Pain in limb: 104 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 223 reports
• Pleural effusion (water on the lungs): 178 reports
• Pneumonia: 462 reports
• Prostate cancer: 162 reports
• Prostatic disorder: 261 reports
• Prostatic specific antigen increased: 121 reports
• Pulmonary oedema (fluid accumulation in the lungs): 140 reports
• Rashes (redness): 358 reports
• Rectal haemorrhage (bleeding from anus): 108 reports
• Renal disorder (kidney disease): 106 reports
• Renal failure acute (rapid kidney dysfunction): 193 reports
• Renal failure chronic (long lasting kidney dysfunction): 131 reports
• Renal impairment (severely reduced kidney function): 201 reports
• Sedation: 165 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 133 reports
• Sinusitis (inflammation of sinus): 134 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 115 reports
• Speech impairment (adult) (inability to speak (adult)): 132 reports
• Stable angina (a constant chest pain): 111 reports
• Stress and anxiety: 363 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 278 reports
• Swallowing difficulty: 133 reports
• Sweating increased (excess sweating): 112 reports
• Swelling: 107 reports
• Thrombocytopenia (decrease of platelets in blood): 316 reports
• Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 132 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 247 reports
• Tricuspid valve incompetence (inefficient heart valve): 112 reports
• Upper respiratory tract infection: 116 reports
• Urinary frequency: 137 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 162 reports
• Urinary retention (the inability to completely or partially empty the bladder): 163 reports
• Urinary tract infection: 205 reports
• Urination - excessive at night: 172 reports
• Urination - painful: 184 reports
• Vision blurred: 213 reports
• Weakness: 1,123 reports
• Weight decreased: 367 reports
• Weight increased: 253 reports

• Ototoxicity (1,631 reports)

All the drugs that are associated with Ototoxicity:

• Ototoxicity (599 drugs)

All the conditions that are associated with Ototoxicity:

• Ototoxicity (337 conditions)

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