Carpine and Nasal congestion - a phase IV clinical study of FDA data


Nasal congestion is found among people who take Carpine, especially for people who are female, 60+ old, have been taking the drug for 10+ years.

The phase IV clinical study analyzes which people take Carpine and have Nasal congestion. It is created by eHealthMe based on reports of 4,804 people who have side effects when taking Carpine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 04, 2022

4,804 people reported to have side effects when taking Carpine.
Among them, 28 people (0.58%) have Nasal congestion.

What is Carpine?

Carpine has active ingredients of pilocarpine hydrochloride. eHealthMe is studying from 4,841 Carpine users for its effectiveness, alternative drugs and more.

What is Nasal congestion?

Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels) is found to be associated with 3,014 drugs and 2,208 conditions by eHealthMe.

Number of Carpine and Nasal congestion reports submitted per year:

Could Carpine cause Nasal congestion?

Time on Carpine when people have Nasal congestion *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

Gender of people who have Nasal congestion when taking Carpine *:

  • female: 78.57 %
  • male: 21.43 %

Age of people who have Nasal congestion when taking Carpine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 27.78 %
  • 60+: 55.56 %

Common drugs people take besides Carpine *:

  1. Lyrica: 7 people, 25.00%
  2. Methotrexate: 6 people, 21.43%
  3. Vitamin D: 5 people, 17.86%
  4. Prilosec: 5 people, 17.86%
  5. Synthroid: 5 people, 17.86%
  6. Prevacid: 4 people, 14.29%
  7. Folic Acid: 4 people, 14.29%
  8. Xalatan: 4 people, 14.29%
  9. Cymbalta: 4 people, 14.29%
  10. Calcium: 4 people, 14.29%

Common side effects people have besides Nasal congestion *:

  1. Cough: 7 people, 25.00%
  2. Malaise (a feeling of general discomfort or uneasiness): 7 people, 25.00%
  3. Fatigue (feeling of tiredness): 6 people, 21.43%
  4. Skin Blushing/flushing (a sudden reddening of the face, neck): 6 people, 21.43%
  5. Breathing Difficulty: 6 people, 21.43%
  6. Weight Increased: 6 people, 21.43%
  7. Pain In Extremity: 6 people, 21.43%
  8. Nasopharyngitis (inflammation of the nasopharynx): 5 people, 17.86%
  9. Oropharyngeal Pain: 5 people, 17.86%
  10. Sneezing: 5 people, 17.86%

Common conditions people have *:

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 14.29%
  2. Dry Mouth: 3 people, 10.71%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 10.71%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 10.71%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 10.71%
  6. Immunodeficiency Common Variable: 2 people, 7.14%
  7. Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 7.14%
  8. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.14%
  9. High Blood Cholesterol: 2 people, 7.14%
  10. Depression: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Carpine and have Nasal congestion?

Check whether Nasal congestion is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Nasal congestion and when was it recovered:

Expand to all the drugs that have ingredients of pilocarpine hydrochloride:

Alternative drugs to, pros and cons of Carpine:

Common Carpine side effects:

Browse all side effects of Carpine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Nasal congestion treatments and more:

COVID vaccines that are related to Nasal congestion:

Common drugs associated with Nasal congestion:

All the drugs that are associated with Nasal congestion:

Common conditions associated with Nasal congestion:

All the conditions that are associated with Nasal congestion:

How the study uses the data?

The study uses data from the FDA. It is based on pilocarpine hydrochloride (the active ingredients of Carpine) and Carpine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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