Carvedilol and Decreased immune responsiveness - a phase IV clinical study of FDA data

Summary:

We study 104,094 people who have side effects when taking Carvedilol. Decreased immune responsiveness is found, especially among people who are female, 60+ old, also take Cosentyx and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people take Carvedilol and have Decreased immune responsiveness. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 02, 2023

104,094 people reported to have side effects when taking Carvedilol.
Among them, 58 people (0.06%) have Decreased immune responsiveness.

What is Carvedilol?

Carvedilol has active ingredients of carvedilol. It is used in high blood pressure. Currently, eHealthMe is studying from 106,394 Carvedilol users.

What is Decreased immune responsiveness?

Decreased immune responsiveness is found to be associated with 1,078 drugs and 747 conditions by eHealthMe. Currently, we are studying 10,059 people who have Decreased immune responsiveness.

Number of Carvedilol and Decreased immune responsiveness reports submitted per year:

Could Carvedilol cause Decreased immune responsiveness?

Gender of people who have Decreased immune responsiveness when taking Carvedilol *:

female: 67.24 %
male: 32.76 %

Age of people who have Decreased immune responsiveness when taking Carvedilol *:

Common drugs people take besides Carvedilol *:

Common side effects people have besides Decreased immune responsiveness *:

Pain In Extremity: 22 people, 37.93%
Joint Pain: 19 people, 32.76%
Pain: 17 people, 29.31%
Gait Disturbance: 16 people, 27.59%
Fatigue (feeling of tiredness): 16 people, 27.59%
Peripheral Swelling: 15 people, 25.86%
The Flu (the flu is caused by an influenza virus): 14 people, 24.14%
Blood Glucose Increased: 14 people, 24.14%
Weight Decreased: 12 people, 20.69%
Hypoaesthesia (reduced sense of touch or sensation): 11 people, 18.97%

Common conditions people have *:

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 20.69%
Psoriasis (immune-mediated disease that affects the skin): 8 people, 13.79%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 8.62%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 5 people, 8.62%
Breast Cancer: 4 people, 6.90%
Cardiac Failure: 4 people, 6.90%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 6.90%
Gastritis (inflammation of stomach): 3 people, 5.17%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 5.17%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

Do you take Carvedilol and have Decreased immune responsiveness?

Check whether Decreased immune responsiveness is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .

Related studies

Carvedilol side effects by duration, gender and age:

Carvedilol side effects (106,394 reports)

Decreased immune responsiveness treatments and more:

Decreased immune responsiveness (10,059 reports)

Common drugs associated with Decreased immune responsiveness:

How the study uses the data?

The study uses data from the FDA. It is based on carvedilol (the active ingredients of Carvedilol) and Carvedilol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.