Carvedilol and Fatigue - a phase IV clinical study of FDA data

Summary:

We study 104,094 people who have side effects when taking Carvedilol. Fatigue is found, especially among people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take Entresto and have Cardiac failure.

The phase IV clinical study analyzes which people take Carvedilol and have Fatigue. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 16, 2023

104,094 people reported to have side effects when taking Carvedilol.
Among them, 7,441 people (7.15%) have Fatigue.

What is Carvedilol?

Carvedilol has active ingredients of carvedilol. It is used in high blood pressure. Currently, eHealthMe is studying from 106,394 Carvedilol users.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 5,236 drugs and 6,221 conditions by eHealthMe. Currently, we are studying 905,148 people who have Fatigue.

Number of Carvedilol and Fatigue reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Carvedilol and have Fatigue?

Check whether Fatigue is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .

Related studies

Carvedilol side effects by duration, gender and age:

Carvedilol side effects (106,394 reports)

Fatigue treatments and more:

Fatigue (905,148 reports)

Common drugs associated with Fatigue:

All the drugs that are associated with Fatigue:

Fatigue (5,236 drugs)

Common conditions associated with Fatigue:

Multiple sclerosis: 66,133 reports
Rheumatoid arthritis: 57,989 reports
Multiple myeloma: 30,410 reports
High blood pressure: 29,311 reports
Pain: 23,301 reports

All the conditions that are associated with Fatigue:

Fatigue (6,221 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on carvedilol (the active ingredients of Carvedilol) and Carvedilol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.