Casodex and Metastases to bone - a phase IV clinical study of FDA data

• Casodex (9,974 reports)

• Abdominal pain: 146 reports
• Abdominal pain upper: 127 reports
• Acute kidney failure: 155 reports
• Alanine aminotransferase increased: 118 reports
• Anaemia (lack of blood): 556 reports
• Anhedonia (inability to experience pleasure from activities usually found enjoyable): 207 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 330 reports
• Arrhythmias (irregular heartbeat): 193 reports
• Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 333 reports
• Aspartate aminotransferase increased: 119 reports
• Atelectasis (partial or complete collapse of the lung): 118 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 159 reports
• Back pain: 497 reports
• Balance disorder: 103 reports
• Blood alkaline phosphatase increased: 117 reports
• Blood creatinine increased: 136 reports
• Blood glucose increased: 140 reports
• Blood urea increased: 102 reports
• Bone disorder: 419 reports
• Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 129 reports
• Bone pain: 252 reports
• Breathing difficulty: 535 reports
• Cardiac failure: 190 reports
• Cardiac failure congestive: 175 reports
• Cataract (clouding of the lens inside the eye): 117 reports
• Cellulitis (infection under the skin): 109 reports
• Cerebral infarction (less blood supply to brain resulting tissue damage): 126 reports
• Chest pain: 295 reports
• Chills (felling of cold): 149 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 171 reports
• Confusional state: 210 reports
• Constipation: 381 reports
• Cough: 184 reports
• Death: 698 reports
• Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 106 reports
• Deformity (disfigurement): 103 reports
• Dehydration (dryness resulting from the removal of water): 220 reports
• Dental caries: 122 reports
• Depression: 271 reports
• Diarrhea: 304 reports
• Disease progression: 140 reports
• Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 135 reports
• Dizziness: 423 reports
• Drowsiness: 124 reports
• Drug ineffective: 180 reports
• Emotional distress: 105 reports
• Erection problems: 114 reports
• Fainting (loss of consciousness and postural tone): 223 reports
• Fall: 330 reports
• Fatigue (feeling of tiredness): 746 reports
• Fever: 356 reports
• Gait disturbance: 209 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 143 reports
• General physical health deterioration (weak health status): 178 reports
• Gums - swollen: 117 reports
• Gynecomastia (enlargement of the gland tissue of the male breast): 182 reports
• Haematuria (presence of blood in urine): 258 reports
• Haemoglobin decreased: 211 reports
• Headache (pain in head): 237 reports
• Hearing loss: 124 reports
• Heart attack: 162 reports
• Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 110 reports
• High blood cholesterol: 123 reports
• High blood pressure: 330 reports
• Hot flush (sudden feelings of heat): 359 reports
• Hyperhidrosis (abnormally increased sweating): 149 reports
• Hypoaesthesia (reduced sense of touch or sensation): 203 reports
• Hypokalemia (low potassium): 122 reports
• Hypotension (abnormally low blood pressure): 286 reports
• Impaired healing: 243 reports
• Indigestion: 116 reports
• Infection: 225 reports
• Injury: 355 reports
• Insomnia (sleeplessness): 262 reports
• Interstitial lung disease: 421 reports
• Intervertebral disc degeneration (spinal disc degeneration): 107 reports
• Intervertebral disc protrusion (spinal disc protrusion): 131 reports
• Itching: 109 reports
• Joint pain: 319 reports
• Kidney stones: 106 reports
• Loose tooth: 116 reports
• Loss of consciousness: 111 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 116 reports
• Malaise (a feeling of general discomfort or uneasiness): 285 reports
• Malignant neoplasm progression (cancer tumour came back): 436 reports
• Memory loss: 166 reports
• Metastases to bone (cancer spreads to bone): 415 reports
• Metastases to spine (cancer spreads to spine): 119 reports
• Mitral valve incompetence (inefficient heart valve): 109 reports
• Muscle aches (muscle pain): 165 reports
• Muscle spasms (muscle contraction): 104 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 123 reports
• Nausea (feeling of having an urge to vomit): 419 reports
• Nausea and vomiting: 299 reports
• Neck pain: 134 reports
• Neoplasm malignant (cancer tumour): 123 reports
• Oedema (fluid collection in tissue): 128 reports
• Oedema peripheral (superficial swelling): 249 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 253 reports
• Osteomyelitis (infection of bone): 303 reports
• Osteonecrosis of jaw (death of bone of jaw): 527 reports
• Pain: 693 reports
• Pain in extremity: 240 reports
• Pain in jaw: 332 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 106 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 180 reports
• Pleural effusion (water on the lungs): 174 reports
• Pneumonia: 306 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 135 reports
• Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 127 reports
• Prostate cancer: 441 reports
• Prostate cancer metastatic: 262 reports
• Prostatic specific antigen increased: 519 reports
• Purulent discharge (discharge that contains pus): 107 reports
• Rashes (redness): 248 reports
• Renal cyst (kidney cyst): 166 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 128 reports
• Spinal osteoarthritis (joint cartilage loss in spine): 233 reports
• Stress and anxiety: 529 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 162 reports
• Swallowing difficulty: 177 reports
• Swelling: 188 reports
• Thrombocytopenia (decrease of platelets in blood): 365 reports
• Tooth abscess (pus formation in tooth): 184 reports
• Toothaches (tooth pain): 157 reports
• Tooth disorder (tooth disease): 111 reports
• Tooth extraction: 268 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 112 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 125 reports
• Urinary retention (the inability to completely or partially empty the bladder): 137 reports
• Urinary tract infection: 276 reports
• Urination - painful: 120 reports
• Vision blurred: 116 reports
• Weakness: 683 reports
• Weight decreased: 381 reports

• Metastases to bone (41,891 reports)

• Abraxane: 294 reports
• Acetaminophen: 345 reports
• Actos: 124 reports
• Acyclovir: 144 reports
• Adriamycin pfs: 255 reports
• Advair diskus 100/50: 160 reports
• Advil: 156 reports
• Afinitor: 676 reports
• Albuterol: 293 reports
• Aldactone: 112 reports
• Aleve: 106 reports
• Allegra: 122 reports
• Allopurinol: 248 reports
• Aloxi: 142 reports
• Alprazolam: 271 reports
• Ambien: 785 reports
• Amlodipine: 191 reports
• Amoxicillin: 449 reports
• Anastrozole: 471 reports
• Aranesp: 340 reports
• Aredia: 1,557 reports
• Arimidex: 760 reports
• Aromasin: 721 reports
• Aspirin: 857 reports
• Atenolol: 324 reports
• Ativan: 552 reports
• Augmentin: 193 reports
• Augmentin '125': 111 reports
• Avastin: 618 reports
• Avelox: 176 reports
• Azithromycin: 123 reports
• Bactrim: 120 reports
• Benadryl: 315 reports
• Biaxin: 127 reports
• Bicalutamide: 194 reports
• Calcium: 269 reports
• Capecitabine: 630 reports
• Carboplatin: 708 reports
• Cardizem: 126 reports
• Casodex: 415 reports
• Celebrex: 561 reports
• Celexa: 247 reports
• Cephalexin: 313 reports
• Chlorhexidine gluconate: 236 reports
• Cipro: 184 reports
• Cisplatin: 251 reports
• Claritin: 107 reports
• Cleocin: 126 reports
• Clonazepam: 127 reports
• Colace: 355 reports
• Coreg: 174 reports
• Coumadin: 593 reports
• Crestor: 162 reports
• Cyclophosphamide: 573 reports
• Cymbalta: 253 reports
• Cytoxan: 386 reports
• Decadron: 780 reports
• Demerol: 184 reports
• Dexamethasone: 805 reports
• Diazepam: 139 reports
• Diflucan: 176 reports
• Digoxin: 215 reports
• Dilaudid: 478 reports
• Diovan: 145 reports
• Docetaxel: 635 reports
• Doxil: 145 reports
• Doxycycline: 188 reports
• Duragesic: 421 reports
• Duragesic-100: 292 reports
• Effexor: 375 reports
• Elavil: 167 reports
• Eligard: 218 reports
• Enalapril maleate: 102 reports
• Enbrel: 116 reports
• Etoposide: 137 reports
• Everolimus: 369 reports
• Exemestane: 719 reports
• Exidine: 313 reports
• Famotidine: 156 reports
• Faslodex: 1,145 reports
• Femara: 1,105 reports
• Fentanyl: 455 reports
• Fish oil: 142 reports
• Flagyl: 230 reports
• Flexeril: 226 reports
• Flomax: 201 reports
• Flonase: 151 reports
• Fluconazole: 202 reports
• Fluorouracil: 462 reports
• Fluoxetine: 105 reports
• Folic acid: 295 reports
• Forteo: 121 reports
• Fosamax: 458 reports
• Fulvestrant: 708 reports
• Furosemide: 362 reports
• Gabapentin: 409 reports
• Gemcitabine: 234 reports
• Gemzar: 400 reports
• Glucophage: 133 reports
• Heparin: 230 reports
• Herceptin: 728 reports
• Humira: 143 reports
• Hydrochlorothiazide: 336 reports
• Hydrocortisone: 115 reports
• Ibrance: 324 reports
• Ibu: 461 reports
• Ibuprofen: 461 reports
• Iressa: 142 reports
• Keflex: 288 reports
• Ketoconazole: 113 reports
• Klonopin: 138 reports
• Klor-con: 149 reports
• Kytril: 164 reports
• Lactulose: 143 reports
• Lanoxin: 106 reports
• Lansoprazole: 115 reports
• Lantus: 127 reports
• Lasix: 659 reports
• Letrozole: 1,144 reports
• Levaquin: 594 reports
• Levothyroxine sodium: 145 reports
• Lexapro: 476 reports
• Lidocaine: 126 reports
• Lipitor: 536 reports
• Lisinopril: 535 reports
• Lopressor: 127 reports
• Lopurin: 252 reports
• Loraz: 437 reports
• Lorazepam: 439 reports
• Lortab: 396 reports
• Lovenox: 295 reports
• Lunesta: 123 reports
• Lupron: 593 reports
• Lupron depot: 169 reports
• Lyrica: 274 reports
• Magnesium: 209 reports
• Megace: 308 reports
• Megestrol acetate: 166 reports
• Meloxicam: 102 reports
• Metformin: 481 reports
• Methotrexate: 511 reports
• Methylprednisolone: 127 reports
• Metoclopramide: 248 reports
• Metoprolol succinate: 114 reports
• Metoprolol tartrate: 188 reports
• Metronidazole: 201 reports
• Miralax: 217 reports
• Mirtazapine: 124 reports
• Mobic: 129 reports
• Morphine: 903 reports
• Morphine sulfate: 310 reports
• Motrin: 178 reports
• Ms contin: 344 reports
• Mucinex: 132 reports
• Multivitamin: 121 reports
• Naproxen: 200 reports
• Nasonex: 119 reports
• Navelbine: 495 reports
• Neulasta: 235 reports
• Neupogen: 227 reports
• Neurontin: 480 reports
• Nexavar: 167 reports
• Nexium: 573 reports
• Nolvadex: 140 reports
• Norco: 172 reports
• Norvasc: 255 reports
• Novolog: 121 reports
• Nystatin: 174 reports
• Omeprazole: 465 reports
• Ondansetron: 268 reports
• Oxycodone: 624 reports
• Oxycontin: 739 reports
• Paclitaxel: 723 reports
• Pamidronate disodium: 130 reports
• Pantoprazole: 304 reports
• Paracetamol: 148 reports
• Paxil: 350 reports
• Pepcid: 246 reports
• Percocet: 584 reports
• Peridex: 365 reports
• Phenergan: 320 reports
• Plavix: 174 reports
• Prednisolone: 218 reports
• Prednisone: 1,039 reports
• Premarin: 193 reports
• Prempro: 116 reports
• Prevacid: 275 reports
• Prilosec: 504 reports
• Prochlorperazine: 131 reports
• Prolia: 117 reports
• Protonix: 602 reports
• Provera: 121 reports
• Prozac: 240 reports
• Ramipril: 113 reports
• Ranitidine: 150 reports
• Reglan: 307 reports
• Remeron: 105 reports
• Remicade: 103 reports
• Restoril: 174 reports
• Revlimid: 216 reports
• Ritalin: 112 reports
• Rocephin: 144 reports
• Sandostatin: 361 reports
• Sandostatin lar: 273 reports
• Senna: 132 reports
• Simvastatin: 283 reports
• Singulair: 122 reports
• Skelaxin: 129 reports
• Solu-medrol: 125 reports
• Soma: 123 reports
• Spiriva: 153 reports
• Spironolactone: 111 reports
• Sutent: 150 reports
• Synthroid: 417 reports
• Tagrisso: 134 reports
• Tamoxifen citrate: 718 reports
• Tarceva: 148 reports
• Taxol: 696 reports
• Taxotere: 943 reports
• Temaz: 211 reports
• Temazepam: 210 reports
• Toprol-xl: 154 reports
• Toradol: 169 reports
• Tramadol: 300 reports
• Tykerb: 162 reports
• Tylenol: 465 reports
• Ultram: 134 reports
• Valium: 182 reports
• Velcade: 125 reports
• Vicodin: 522 reports
• Vinorelbine: 200 reports
• Vioxx: 238 reports
• Vitamin d: 240 reports
• Vitamins: 462 reports
• Votrient: 130 reports
• Warfarin sodium: 264 reports
• Wellbutrin: 260 reports
• Xanax: 495 reports
• Xeloda: 1,072 reports
• Xgeva: 665 reports
• Xofigo: 247 reports
• Xtandi: 220 reports
• Zantac: 281 reports
• Zithromax: 249 reports
• Zocor: 285 reports
• Zofran: 675 reports
• Zoladex: 507 reports
• Zoledronic: 450 reports
• Zoledronic acid: 447 reports
• Zoloft: 443 reports
• Zolpidem: 215 reports
• Zometa: 3,750 reports
• Zyrtec: 210 reports
• Zytiga: 169 reports

All the drugs that are associated with Metastases to bone:

• Metastases to bone (1,553 drugs)

• Acupuncture and pain: 443 reports
• Adenocarcinoma of renal cells: 290 reports
• Anxiety: 185 reports
• Anxiety and stress: 185 reports
• Arthritis - rheumatoid: 277 reports
• Blood cholesterol abnormal: 149 reports
• Blood cholesterol increased: 149 reports
• Blood pressure increased: 528 reports
• Blood triglycerides abnormal: 153 reports
• Blood triglycerides increased: 153 reports
• Bone disorder: 113 reports
• Breast cancer: 1,770 reports
• Breast cancer female: 238 reports
• Breast cancer metastatic: 1,427 reports
• Cancer - breast: 1,761 reports
• Cancer pain: 113 reports
• Cancer - prostate: 988 reports
• Carcinoma - ductal: 1,893 reports
• Constipation: 145 reports
• Depression: 242 reports
• Diabetes: 195 reports
• Diabetes mellitus: 221 reports
• Diabetes mellitus non-insulin-dependent: 127 reports
• Dm: 221 reports
• Hbp: 505 reports
• High blood cholesterol: 153 reports
• High blood pressure: 505 reports
• Hypercholesterolaemia: 149 reports
• Hypernephroma: 290 reports
• Hypertension: 507 reports
• Jitters: 185 reports
• Lack of regular bowel movements: 148 reports
• Lung cancer - non-small cell: 319 reports
• Lung neoplasm malignant: 214 reports
• Metastases to bone: 931 reports
• Metastatic renal cell carcinoma: 142 reports
• Ms: 193 reports
• Multiple myeloma: 260 reports
• Multiple sclerosis: 196 reports
• Nausea: 126 reports
• Neoplasm malignant: 243 reports
• Neuroendocrine tumor: 138 reports
• Osteoporosis: 529 reports
• Pain: 651 reports
• Plasma cell myeloma: 262 reports
• Preventive health care: 193 reports
• Prostate cancer: 1,001 reports
• Prostate cancer metastatic: 315 reports
• Ra: 283 reports
• Renal cancer: 290 reports
• Renal cell carcinoma: 309 reports
• Rheumatoid arthritis: 283 reports
• Stress: 185 reports
• Stress and anxiety: 185 reports
• Type 2 diabetes: 177 reports
• Type 2 diabetes mellitus: 177 reports

All the conditions that are associated with Metastases to bone:

• Metastases to bone (838 conditions)

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