Casodex and Yellow skin and eyes - a phase IV clinical study of FDA data
Summary:
Yellow skin and eyes is found among people who take Casodex, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Casodex and have Yellow skin and eyes. It is created by eHealthMe based on reports of 10,174 people who have side effects when taking Casodex from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
10,174 people reported to have side effects when taking Casodex.
Among them, 39 people (0.38%) have Yellow skin and eyes.
What is Casodex?
Casodex has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 10,303 Casodex users for its effectiveness, alternative drugs and more.
What is Yellow skin and eyes?
Yellow skin and eyes is found to be associated with 2,926 drugs and 2,890 conditions by eHealthMe.
Number of Casodex and Yellow skin and eyes reports submitted per year:

Time on Casodex when people have Yellow skin and eyes *:
- < 1 month: 17.86 %
- 1 - 6 months: 53.57 %
- 6 - 12 months: 14.29 %
- 1 - 2 years: 10.71 %
- 2 - 5 years: 3.57 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Yellow skin and eyes when taking Casodex *:
- female: 2.63 %
- male: 97.37 %
Age of people who have Yellow skin and eyes when taking Casodex *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 2.94 %
- 60+: 97.06 %
Common drugs people take besides Casodex *:
- Zoladex: 11 people, 28.21%
- Taxotere: 3 people, 7.69%
- Zometa: 2 people, 5.13%
- Phenergan: 2 people, 5.13%
- Augmentin '125': 2 people, 5.13%
- Coumadin: 2 people, 5.13%
- Fosamax: 2 people, 5.13%
- Lupron: 2 people, 5.13%
- Lupron Depot: 2 people, 5.13%
- Marinol: 2 people, 5.13%
Common side effects people have besides Yellow skin and eyes *:
- Aspartate Aminotransferase Increased: 11 people, 28.21%
- Alanine Aminotransferase Increased: 10 people, 25.64%
- Ascites (accumulation of fluid in the abdominal cavity): 8 people, 20.51%
- Blood Bilirubin Increased: 6 people, 15.38%
- Nausea (feeling of having an urge to vomit): 5 people, 12.82%
- Thrombocytopenia (decrease of platelets in blood): 5 people, 12.82%
- Fatigue (feeling of tiredness): 5 people, 12.82%
- Weakness: 4 people, 10.26%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 10.26%
- Liver Disorder (liver diseases): 4 people, 10.26%
Common conditions people have *:
- Enlarged Prostate: 3 people, 7.69%
- Wound: 2 people, 5.13%
- Metastases To Bone (cancer spreads to bone): 2 people, 5.13%
- Type 2 Diabetes: 1 person, 2.56%
- Prostate Cancer Metastatic: 1 person, 2.56%
- Neoplasm Prostate (tumour of prostate): 1 person, 2.56%
- Metastatic Pain (pain due to cancer spread): 1 person, 2.56%
- High Blood Pressure: 1 person, 2.56%
- Hepatic Function Abnormal: 1 person, 2.56%
- Depression: 1 person, 2.56%
* Approximation only. Some reports may have incomplete information.
Do you take Casodex and have Yellow skin and eyes?
Check whether Yellow skin and eyes is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
Related studies
How severe was Yellow skin and eyes and when was it recovered:
Expand to all the drugs that have ingredients of bicalutamide:
Alternative drugs to, pros and cons of Casodex:
- Casodex (10,303 reports)
Common Casodex side effects:
- Fatigue (feeling of tiredness): 775 reports
- Death: 772 reports
- Pain: 729 reports
- Weakness: 683 reports
- Breathing difficulty: 545 reports
Browse all side effects of Casodex:
a b c d e f g h i j k l m n o p q r s t u v w x y zYellow skin and eyes treatments and more:
- Yellow skin and eyes (31,303 reports)
COVID vaccines that are related to Yellow skin and eyes:
- Yellow skin and eyes in Moderna COVID Vaccine
- Yellow skin and eyes in Pfizer BioNTech Covid Vaccine
- Yellow skin and eyes in Johnson and Johnson Covid Vaccine
Common drugs associated with Yellow skin and eyes:
- Aspirin: 1,304 reports
- Omeprazole: 1,230 reports
- Prednisolone: 1,007 reports
- Prednisone: 984 reports
- Metformin: 961 reports
- Furosemide: 923 reports
- Lipitor: 906 reports
- Augmentin: 866 reports
- Pantoprazole: 772 reports
- Ibu: 762 reports
All the drugs that are associated with Yellow skin and eyes:
- Yellow skin and eyes (2,926 drugs)
Common conditions associated with Yellow skin and eyes:
- High blood pressure: 1,946 reports
- Hiv infection: 978 reports
- Hepatitis c: 949 reports
- Depression: 819 reports
- Pain: 803 reports
- Rheumatoid arthritis: 637 reports
- Diabetes: 623 reports
- Type 2 diabetes: 619 reports
All the conditions that are associated with Yellow skin and eyes:
- Yellow skin and eyes (2,890 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on bicalutamide (the active ingredients of Casodex) and Casodex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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