Cassia senna and Anaphylaxis - a phase IV clinical study of FDA data
Summary:
Anaphylaxis is found among people who take Cassia senna, especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years.
The phase IV clinical study analyzes which people take Cassia senna and have Anaphylaxis. It is created by eHealthMe based on reports of 561 people who have side effects when taking Cassia senna from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
561 people reported to have side effects when taking Cassia senna.
Among them, 6 people (1.07%) have Anaphylaxis.
What is Cassia senna?
Cassia senna has active ingredients of senna. eHealthMe is studying from 563 Cassia senna users for its effectiveness, alternative drugs and more.
What is Anaphylaxis?
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) is found to be associated with 3,064 drugs and 2,570 conditions by eHealthMe.
Number of Cassia senna and Anaphylaxis reports submitted per year:

Time on Cassia senna when people have Anaphylaxis *:
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 100 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Anaphylaxis when taking Cassia senna *:
- female: 16.67 %
- male: 83.33 %
Age of people who have Anaphylaxis when taking Cassia senna *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 16.67 %
- 60+: 83.33 %
Common drugs people take besides Cassia senna *:
- Paracetamol: 3 people, 50.00%
- Alendronic Acid: 2 people, 33.33%
- Zopiclone: 1 person, 16.67%
- Ventolin: 1 person, 16.67%
- Fluoxetine: 1 person, 16.67%
- Amlodipine: 1 person, 16.67%
- Acetylsalicylic Acid: 1 person, 16.67%
Common side effects people have besides Anaphylaxis *:
- Abdominal Discomfort: 2 people, 33.33%
Common conditions people have *:
- Osteoporosis (bones weak and more likely to break): 3 people, 50.00%
- Constipation: 1 person, 16.67%
- Breathing Difficulty: 1 person, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Cassia senna and have Anaphylaxis?
Check whether Anaphylaxis is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- An?eli? N, Erdeljan S, Popovi? R, Bo?i? T, "Anaphylaxis on graft reperfusion during orthotopic liver transplantation: A case study", Srpski arhiv za celokupno lekarstvo, 2016 Jan .
- Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
- Guensley Delva, M. D., & Muse, I, "Rare case of laryngeal edema and anaphylaxis to Ofirmev (IV Acetaminophen): Case Report", , 2012 Jan .
- Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .
Related studies
How severe was Anaphylaxis and when was it recovered:
Expand to all the drugs that have ingredients of senna:
- Anaphylaxis and drugs with ingredients of senna (90 reports)
Alternative drugs to, pros and cons of Cassia senna:
- Cassia senna (563 reports)
Anaphylaxis treatments and more:
- Anaphylaxis (78,713 reports)
COVID vaccines that are related to Anaphylaxis:
- Anaphylaxis in Moderna COVID Vaccine
- Anaphylaxis in Pfizer BioNTech Covid Vaccine
- Anaphylaxis in Johnson and Johnson Covid Vaccine
Common drugs associated with Anaphylaxis:
- Xolair: 3,904 reports
- Methotrexate: 3,245 reports
- Prednisone: 3,046 reports
- Propofol: 3,042 reports
- Humira: 2,285 reports
- Remicade: 2,253 reports
- Enbrel: 1,915 reports
- Aspirin: 1,888 reports
- Ibu: 1,887 reports
- Ibuprofen: 1,885 reports
All the drugs that are associated with Anaphylaxis:
- Anaphylaxis (3,064 drugs)
Common conditions associated with Anaphylaxis:
- Asthma: 3,126 reports
- Rheumatoid arthritis: 3,028 reports
- High blood pressure: 2,212 reports
- Multiple sclerosis: 2,127 reports
- Pain: 1,541 reports
- Crohn's disease: 1,179 reports
All the conditions that are associated with Anaphylaxis:
- Anaphylaxis (2,570 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on senna (the active ingredients of Cassia senna) and Cassia senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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