Cefazolin and Ototoxicity - a phase IV clinical study of FDA data

Summary:

Ototoxicity is found among people who take Cefazolin, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Cefazolin and have Ototoxicity. It is created by eHealthMe based on reports of 12,902 people who have side effects when taking Cefazolin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Aug, 19, 2022

12,902 people reported to have side effects when taking Cefazolin.
Among them, 6 people (0.05%) have Ototoxicity.


What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 11,815 Cefazolin users for its effectiveness, alternative drugs and more.

What is Ototoxicity?

Ototoxicity (damage to the ear) is found to be associated with 599 drugs and 337 conditions by eHealthMe.

Number of Cefazolin and Ototoxicity reports submitted per year:

Could Cefazolin cause Ototoxicity?

Time on Cefazolin when people have Ototoxicity *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Ototoxicity when taking Cefazolin *:

  • female: 16.67 %
  • male: 83.33 %

Age of people who have Ototoxicity when taking Cefazolin *:

  • 0-1: 0.0 %
  • 2-9: 33.33 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 16.67 %
  • 60+: 33.33 %

Common drugs people take besides Cefazolin *:

  1. Timentin: 2 people, 33.33%
  2. Ondansetron: 2 people, 33.33%
  3. Morphine: 2 people, 33.33%
  4. Codeine: 2 people, 33.33%
  5. Vancomycin: 1 person, 16.67%
  6. Paracetamol: 1 person, 16.67%
  7. Heparin: 1 person, 16.67%
  8. Gentamicin: 1 person, 16.67%

Common side effects people have besides Ototoxicity *:

  1. Neurosensory Hypoacusis (a type of hearing loss in which the root cause lies in the vestibulocochlear nerve): 2 people, 33.33%
  2. Dizziness: 2 people, 33.33%
  3. Vestibular Disorder (disorders of the body's balance (vestibular) system in the inner ear): 1 person, 16.67%
  4. Small Intestinal Obstruction (blockage in small intestine): 1 person, 16.67%
  5. Renal Failure Acute (rapid kidney dysfunction): 1 person, 16.67%
  6. Leukopenia (less number of white blood cells in blood): 1 person, 16.67%
  7. Hypoacusis (loss of hearing): 1 person, 16.67%
  8. Deafness Neurosensory: 1 person, 16.67%

Common conditions people have *:

  1. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 2 people, 33.33%
  2. Medulloblastoma (a fast-growing, high-grade tumour that always begins in the cerebellum): 2 people, 33.33%
  3. Arthritis Infective (purulent invasion of a joint by an infectious agent which produces arthritis): 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Cefazolin and have Ototoxicity?

Check whether Ototoxicity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Ototoxicity and when was it recovered:

Expand to all the drugs that have ingredients of cefazolin sodium:

Alternative drugs to, pros and cons of Cefazolin:

Common Cefazolin side effects:

Browse all side effects of Cefazolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Ototoxicity treatments and more:

COVID vaccines that are related to Ototoxicity:

Common drugs associated with Ototoxicity:

All the drugs that are associated with Ototoxicity:

All the conditions that are associated with Ototoxicity:

How the study uses the data?

The study uses data from the FDA. It is based on cefazolin sodium (the active ingredients of Cefazolin) and Cefazolin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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