Ceftriaxone and Crohn's disease - a phase IV clinical study of FDA data
Crohn's disease is found among people who take Ceftriaxone, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Ceftriaxone and have Crohn's disease. It is created by eHealthMe based on reports of 33,453 people who have side effects when taking Ceftriaxone from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
33,453 people reported to have side effects when taking Ceftriaxone.
Among them, 65 people (0.19%) have Crohn's disease.
What is Ceftriaxone?
Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 33,567 Ceftriaxone users for its effectiveness, alternative drugs and more.
What is Crohn's disease?
Crohn's disease (condition that causes inflammation of the gastrointestinal tract) is found to be associated with 2,462 drugs and 1,949 conditions by eHealthMe.
Number of Ceftriaxone and Crohn's disease reports submitted per year:
Time on Ceftriaxone when people have Crohn's disease *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Crohn's disease when taking Ceftriaxone *:
- female: 68.09 %
- male: 31.91 %
Age of people who have Crohn's disease when taking Ceftriaxone *:
- 0-1: 0.0 %
- 2-9: 9.3 %
- 10-19: 13.95 %
- 20-29: 0.0 %
- 30-39: 16.28 %
- 40-49: 4.65 %
- 50-59: 6.98 %
- 60+: 48.84 %
Common drugs people take besides Ceftriaxone *:
- Zopiclone: 11 people, 16.92%
- Imuran: 9 people, 13.85%
- Flagyl: 6 people, 9.23%
- Inflectra: 6 people, 9.23%
- Vancomycin: 5 people, 7.69%
- Humira: 5 people, 7.69%
- Metronidazole: 5 people, 7.69%
- Morphine: 4 people, 6.15%
- Prednisolone: 3 people, 4.62%
- Acetaminophen: 3 people, 4.62%
Common side effects people have besides Crohn's disease *:
- Haematochezia (passage of stools containing blood): 30 people, 46.15%
- Diarrhea: 29 people, 44.62%
- Muscle Aches (muscle pain): 28 people, 43.08%
- Joint Pain: 27 people, 41.54%
- Anal Fissure: 27 people, 41.54%
- Proctalgia (pain in the rectum): 27 people, 41.54%
- Weight Increased: 11 people, 16.92%
- Canker Sores (painful, open sore in the mouth): 11 people, 16.92%
- Anaemia (lack of blood): 9 people, 13.85%
- Gastric Ulcer (stomach ulcer): 9 people, 13.85%
Common conditions people have *:
- Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 4 people, 6.15%
- Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 4.62%
- Bacterial Infection: 3 people, 4.62%
- Urinary Tract Infection: 2 people, 3.08%
- Acne (skin problems that cause pimples): 2 people, 3.08%
- Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 1.54%
- Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 1.54%
- Anal Fistula: 1 person, 1.54%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 1.54%
- Campylobacter Infection (infection by the campylobacter bacterium): 1 person, 1.54%
* Approximation only. Some reports may have incomplete information.
Do you take Ceftriaxone and have Crohn's disease?Check whether Crohn's disease is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How severe was Crohn's disease and when was it recovered:
Expand to all the drugs that have ingredients of ceftriaxone sodium:
Alternative drugs to, pros and cons of Ceftriaxone:
- Ceftriaxone (33,567 reports)
Common Ceftriaxone side effects:
- Fever: 2,393 reports
- Drug ineffective: 1,874 reports
- Pneumonia: 1,715 reports
- Rashes (redness): 1,662 reports
- Breathing difficulty: 1,364 reports
- Thrombocytopenia (decrease of platelets in blood): 1,275 reports
- Diarrhea: 1,256 reports
- Hypotension (abnormally low blood pressure): 1,244 reports
Browse all side effects of Ceftriaxone:a b c d e f g h i j k l m n o p q r s t u v w x y z
Crohn's disease treatments and more:
- Crohn's disease (311,574 reports)
COVID vaccines that are related to Crohn's disease:
- Crohn's disease in Moderna COVID Vaccine
- Crohn's disease in Pfizer BioNTech Covid Vaccine
- Crohn's disease in Johnson and Johnson Covid Vaccine
Common drugs associated with Crohn's disease:
- Humira: 20,999 reports
- Remicade: 8,065 reports
- Prednisone: 7,967 reports
- Accutane: 7,519 reports
- Methotrexate: 4,579 reports
- Stelara: 3,791 reports
- Cimzia: 3,233 reports
- Azathioprine: 2,554 reports
- Imuran: 1,872 reports
- Pentasa: 1,718 reports
All the drugs that are associated with Crohn's disease:
- Crohn's disease (2,462 drugs)
Common conditions associated with Crohn's disease:
- Acne: 4,791 reports
- Rheumatoid arthritis: 1,983 reports
- Pain: 1,966 reports
- High blood pressure: 1,721 reports
All the conditions that are associated with Crohn's disease:
- Crohn's disease (1,949 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ceftriaxone sodium (the active ingredients of Ceftriaxone) and Ceftriaxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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