Cefuroxime and Intestinal ischaemia - a phase IV clinical study of FDA data
Summary:
Intestinal ischaemia is found among people who take Cefuroxime, especially for people who are male, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Cefuroxime and have Intestinal ischaemia. It is created by eHealthMe based on reports of 12,467 people who have side effects when taking Cefuroxime from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
12,467 people reported to have side effects when taking Cefuroxime.
Among them, 57 people (0.46%) have Intestinal ischaemia.
What is Cefuroxime?
Cefuroxime has active ingredients of cefuroxime sodium. It is often used in sinusitis. eHealthMe is studying from 12,644 Cefuroxime users for its effectiveness, alternative drugs and more.
What is Intestinal ischaemia?
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines) is found to be associated with 1,234 drugs and 784 conditions by eHealthMe.
Number of Cefuroxime and Intestinal ischaemia reports submitted per year:

Time on Cefuroxime when people have Intestinal ischaemia *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Intestinal ischaemia when taking Cefuroxime *:
- female: 27.27 %
- male: 72.73 %
Age of people who have Intestinal ischaemia when taking Cefuroxime *:
- 0-1: 0.0 %
- 2-9: 31.48 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 1.85 %
- 40-49: 1.85 %
- 50-59: 3.7 %
- 60+: 61.11 %
Common drugs people take besides Cefuroxime *:
- Pulmozyme: 15 people, 26.32%
- Propofol: 12 people, 21.05%
- Morphine: 12 people, 21.05%
- Acetaminophen: 11 people, 19.30%
- Aspirin: 11 people, 19.30%
- Pantoprazole: 11 people, 19.30%
- Piperacillin And Tazobactam: 11 people, 19.30%
- Simvastatin: 11 people, 19.30%
- Metronidazole: 10 people, 17.54%
- Furosemide: 9 people, 15.79%
Common side effects people have besides Intestinal ischaemia *:
- Fever: 29 people, 50.88%
- Cerebral Ischaemia (insufficient blood flow to the brain to meet metabolic demand): 19 people, 33.33%
- Injury: 19 people, 33.33%
- Diarrhea: 19 people, 33.33%
- Dehydration (dryness resulting from the removal of water): 18 people, 31.58%
- Pneumococcal Sepsis (pneumococcal sepsis is a serious medical condition where bacteria, specifically streptococcus pneumoniae): 18 people, 31.58%
- Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 18 people, 31.58%
- Circulatory Collapse: 18 people, 31.58%
- Breathing Difficulty: 18 people, 31.58%
- Breathing - Slowed Or Stopped: 18 people, 31.58%
Common conditions people have *:
- Interstitial Lung Disease: 18 people, 31.58%
- Breathing - Slowed Or Stopped: 18 people, 31.58%
- Pneumococcal Sepsis (pneumococcal sepsis is a serious medical condition where bacteria, specifically streptococcus pneumoniae): 18 people, 31.58%
- Nausea And Vomiting: 18 people, 31.58%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 11 people, 19.30%
- High Blood Cholesterol: 11 people, 19.30%
- Infection: 10 people, 17.54%
- Enlarged Prostate: 10 people, 17.54%
- Hyperchlorhydria (gastric acid levels are higher in stomach): 10 people, 17.54%
- Nausea (feeling of having an urge to vomit): 9 people, 15.79%
* Approximation only. Some reports may have incomplete information.
Do you take Cefuroxime and have Intestinal ischaemia?
Check whether Intestinal ischaemia is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Intestinal ischaemia and when was it recovered:
Expand to all the drugs that have ingredients of cefuroxime sodium:
Alternative drugs to, pros and cons of Cefuroxime:
- Cefuroxime (12,644 reports)
Common Cefuroxime side effects:
- Pneumonia: 793 reports
- Acute kidney failure: 742 reports
- Fever: 710 reports
- Diarrhea: 686 reports
- Breathing difficulty: 685 reports
- Rashes (redness): 683 reports
- Chronic kidney disease: 588 reports
- Hypotension (abnormally low blood pressure): 567 reports
- Drug ineffective: 559 reports
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 550 reports
Browse all side effects of Cefuroxime:
a b c d e f g h i j k l m n o p q r s t u v w x y zIntestinal ischaemia treatments and more:
- Intestinal ischaemia (6,462 reports)
COVID vaccines that are related to Intestinal ischaemia:
- Intestinal ischaemia in Moderna COVID Vaccine
- Intestinal ischaemia in Pfizer BioNTech Covid Vaccine
- Intestinal ischaemia in Johnson and Johnson Covid Vaccine
Common drugs associated with Intestinal ischaemia:
- Aspirin: 363 reports
- Prednisone: 309 reports
- Metformin: 303 reports
- Furosemide: 272 reports
- Omeprazole: 268 reports
- Propofol: 254 reports
- Lisinopril: 248 reports
- Amlodipine: 213 reports
- Lasix: 210 reports
- Lansoprazole: 200 reports
All the drugs that are associated with Intestinal ischaemia:
- Intestinal ischaemia (1,234 drugs)
Common conditions associated with Intestinal ischaemia:
- High blood pressure: 365 reports
- Atrial fibrillation/flutter: 277 reports
- Rheumatoid arthritis: 273 reports
- Pain: 191 reports
- Multiple myeloma: 155 reports
- High blood cholesterol: 137 reports
All the conditions that are associated with Intestinal ischaemia:
- Intestinal ischaemia (784 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on cefuroxime sodium (the active ingredients of Cefuroxime) and Cefuroxime (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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