Celebrex and Dupuytren's contracture - a phase IV clinical study of FDA data


Dupuytren's contracture is reported only by a few people who take Celebrex.

The phase IV clinical study analyzes which people take Celebrex and have Dupuytren's contracture. It is created by eHealthMe based on reports of 131,081 people who have side effects while taking Celebrex from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 14, 2022

131,081 people reported to have side effects when taking Celebrex.
Among them, 5 people (0.0%) have Dupuytren's contracture.

What is Celebrex?

Celebrex has active ingredients of celecoxib. It is often used in arthritis. eHealthMe is studying from 134,390 Celebrex users for its effectiveness, alternative drugs and more.

What is Dupuytren's contracture?

Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 441 drugs and 204 conditions by eHealthMe.

Number of Celebrex and Dupuytren's contracture reports submitted per year:

Could Celebrex cause Dupuytren's contracture?

Time on Celebrex when people have Dupuytren's contracture *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Dupuytren's contracture when taking Celebrex *:

  • female: 40 %
  • male: 60 %

Age of people who have Dupuytren's contracture when taking Celebrex *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Celebrex *:

  1. Zocor: 2 people, 40.00%
  2. Norvasc: 2 people, 40.00%
  3. Avapro: 2 people, 40.00%
  4. Actonel: 2 people, 40.00%
  5. Xiaflex: 1 person, 20.00%
  6. Vioxx: 1 person, 20.00%
  7. Thiamine Hydrochloride: 1 person, 20.00%
  8. Relafen: 1 person, 20.00%
  9. Oruvail: 1 person, 20.00%
  10. Micardis: 1 person, 20.00%

Common side effects people have besides Dupuytren's contracture *:

  1. Hypersensitivity: 2 people, 40.00%
  2. Heart Rate Decreased: 2 people, 40.00%
  3. Purpura (purplish discoloration of the skin): 2 people, 40.00%
  4. High Blood Pressure: 2 people, 40.00%
  5. Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs): 1 person, 20.00%
  6. Hepatic Steatosis (fatty liver disease): 1 person, 20.00%
  7. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 1 person, 20.00%
  8. Chest Pain: 1 person, 20.00%
  9. Head Injury: 1 person, 20.00%
  10. Haemoglobin Decreased: 1 person, 20.00%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 40.00%
  2. Vitamin B12 Deficiency: 1 person, 20.00%
  3. Rickets (softening of bones): 1 person, 20.00%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 20.00%
  5. Psoriasis (immune-mediated disease that affects the skin): 1 person, 20.00%
  6. Osteoporotic Fracture (fracture due to weak bone): 1 person, 20.00%
  7. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 1 person, 20.00%
  8. Joint Pain: 1 person, 20.00%
  9. High Blood Pressure: 1 person, 20.00%
  10. Back Pain: 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Celebrex and have Dupuytren's contracture?

Check whether Dupuytren's contracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Celebrex:

Dupuytren's contracture treatments and more:

COVID vaccines that are related to Dupuytren's contracture:

How severe was Dupuytren's contracture and when was it recovered:

Expand to all the drugs that have ingredients of celecoxib:

Common drugs associated with Dupuytren's contracture:

All the drugs that are associated with Dupuytren's contracture:

All the conditions that are associated with Dupuytren's contracture:

How the study uses the data?

The study uses data from the FDA. It is based on celecoxib (the active ingredients of Celebrex) and Celebrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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