Celebrex and Ototoxicity - a phase IV clinical study of FDA data


Ototoxicity is found among people who take Celebrex, especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years.

The phase IV clinical study analyzes which people take Celebrex and have Ototoxicity. It is created by eHealthMe based on reports of 131,081 people who have side effects when taking Celebrex from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 01, 2022

131,081 people reported to have side effects when taking Celebrex.
Among them, 10 people (0.01%) have Ototoxicity.

What is Celebrex?

Celebrex has active ingredients of celecoxib. It is often used in arthritis. eHealthMe is studying from 134,390 Celebrex users for its effectiveness, alternative drugs and more.

What is Ototoxicity?

Ototoxicity (damage to the ear) is found to be associated with 598 drugs and 335 conditions by eHealthMe.

Number of Celebrex and Ototoxicity reports submitted per year:

Could Celebrex cause Ototoxicity?

Time on Celebrex when people have Ototoxicity *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Ototoxicity when taking Celebrex *:

  • female: 30 %
  • male: 70 %

Age of people who have Ototoxicity when taking Celebrex *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 12.5 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 87.5 %

Common drugs people take besides Celebrex *:

  1. Advil: 5 people, 50.00%
  2. Zydelig: 3 people, 30.00%
  3. Vitamin D: 1 person, 10.00%
  4. Vitamin C: 1 person, 10.00%
  5. Amitriptyline Hydrochloride: 1 person, 10.00%
  6. Baby Aspirin: 1 person, 10.00%
  7. Buspirone Hcl: 1 person, 10.00%
  8. Clopidogrel Bisulfate: 1 person, 10.00%
  9. Cymbalta: 1 person, 10.00%
  10. Fish Oil: 1 person, 10.00%

Common side effects people have besides Ototoxicity *:

  1. Dizziness: 7 people, 70.00%
  2. Fall: 7 people, 70.00%
  3. Thrombosis (formation of a blood clot inside a blood vessel): 6 people, 60.00%
  4. Blood Urine Present: 6 people, 60.00%
  5. Haemorrhage (bleeding): 6 people, 60.00%
  6. Abdominal Distension: 5 people, 50.00%
  7. Accident: 5 people, 50.00%
  8. Intestinal Obstruction: 5 people, 50.00%
  9. Rib Fracture: 5 people, 50.00%
  10. Oral Infection: 4 people, 40.00%

Common conditions people have *:

  1. Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 50.00%
  2. Non-Hodgkin's Lymphoma Unspecified Histology Indolent (malignant (cancer) cells form in the lymph system- unspecified histology indolent): 1 person, 10.00%
  3. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 10.00%
  4. Cervicobrachial Syndrome (pain in neck and arm with changing location): 1 person, 10.00%
  5. Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Celebrex and have Ototoxicity?

Check whether Ototoxicity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Ototoxicity and when was it recovered:

Expand to all the drugs that have ingredients of celecoxib:

Alternative drugs to, pros and cons of Celebrex:

Common Celebrex side effects:

Browse all side effects of Celebrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Ototoxicity treatments and more:

COVID vaccines that are related to Ototoxicity:

Common drugs associated with Ototoxicity:

All the drugs that are associated with Ototoxicity:

All the conditions that are associated with Ototoxicity:

How the study uses the data?

The study uses data from the FDA. It is based on celecoxib (the active ingredients of Celebrex) and Celebrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: