Chloroquine phosphate and Ototoxicity - a phase IV clinical study of FDA data


Ototoxicity is reported only by a few people who take Chloroquine Phosphate.

The phase IV clinical study analyzes which people take Chloroquine phosphate and have Ototoxicity. It is created by eHealthMe based on reports of 998 people who have side effects while taking Chloroquine phosphate from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 20, 2022

998 people reported to have side effects when taking Chloroquine phosphate.
Among them, 2 people (0.2%) have Ototoxicity.

What is Chloroquine phosphate?

Chloroquine phosphate has active ingredients of chloroquine phosphate. It is often used in malaria. eHealthMe is studying from 1,031 Chloroquine phosphate users for its effectiveness, alternative drugs and more.

What is Ototoxicity?

Ototoxicity (damage to the ear) is found to be associated with 599 drugs and 337 conditions by eHealthMe.

Number of Chloroquine phosphate and Ototoxicity reports submitted per year:

Could Chloroquine phosphate cause Ototoxicity?

Gender of people who have Ototoxicity when taking Chloroquine phosphate *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Ototoxicity when taking Chloroquine phosphate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 50 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 50 %
  • 60+: 0.0 %

Common drugs people take besides Chloroquine phosphate *:

  1. Prednisolone: 1 person, 50.00%
  2. Indomethacin: 1 person, 50.00%

Common side effects people have besides Ototoxicity *:

  1. Tinnitus (a ringing in the ears): 1 person, 50.00%
  2. Red Blood Cell Sedimentation Rate Increased: 1 person, 50.00%
  3. Hypoacusis (loss of hearing): 1 person, 50.00%
  4. C-Reactive Protein Increased: 1 person, 50.00%
  5. Abortion Spontaneous (naturally occurring miscarriage): 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Chloroquine phosphate and have Ototoxicity?

Check whether Ototoxicity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Ototoxicity and when was it recovered:

Expand to all the drugs that have ingredients of chloroquine phosphate:

Alternative drugs to, pros and cons of Chloroquine phosphate:

Ototoxicity treatments and more:

COVID vaccines that are related to Ototoxicity:

Common drugs associated with Ototoxicity:

All the drugs that are associated with Ototoxicity:

All the conditions that are associated with Ototoxicity:

How the study uses the data?

The study uses data from the FDA. It is based on chloroquine phosphate (the active ingredients of Chloroquine phosphate) and Chloroquine phosphate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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