Cialis and Dupuytren's contracture - a phase IV clinical study of FDA data
Summary:
Dupuytren's contracture is reported only by a few people who take Cialis.
The phase IV clinical study analyzes which people take Cialis and have Dupuytren's contracture. It is created by eHealthMe based on reports of 25,110 people who have side effects while taking Cialis from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
25,110 people reported to have side effects when taking Cialis.
Among them, 4 people (0.02%) have Dupuytren's contracture.
What is Cialis?
Cialis has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 26,218 Cialis users for its effectiveness, alternative drugs and more.
What is Dupuytren's contracture?
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 445 drugs and 208 conditions by eHealthMe.
Number of Cialis and Dupuytren's contracture reports submitted per year:
Time on Cialis when people have Dupuytren's contracture *:
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 100 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Dupuytren's contracture when taking Cialis *:
- female: 25 %
- male: 75 %
Age of people who have Dupuytren's contracture when taking Cialis *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 100 %
Common drugs people take besides Cialis *:
- Lipitor: 2 people, 50.00%
- Zolpidem: 1 person, 25.00%
- Zoloft: 1 person, 25.00%
- Allegra Allergy: 1 person, 25.00%
- Claritin: 1 person, 25.00%
- Effexor: 1 person, 25.00%
- Forteo: 1 person, 25.00%
- Glucophage: 1 person, 25.00%
- Januvia: 1 person, 25.00%
- Levitra: 1 person, 25.00%
Common side effects people have besides Dupuytren's contracture *:
- Visual Impairment: 1 person, 25.00%
- Swallowing Difficulty: 1 person, 25.00%
- Blepharochalasis (inflammation of the eyelid that is characterized by exacerbations and remissions of eyelid oedema): 1 person, 25.00%
- Blood Potassium Decreased: 1 person, 25.00%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 25.00%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 25.00%
- Death: 1 person, 25.00%
- Diabetic Amyotrophy (painful asymmetrical proximal motor neuropathy affecting the lower limbs): 1 person, 25.00%
- Fatigue (feeling of tiredness): 1 person, 25.00%
- Gallstones (stone formation by bile component): 1 person, 25.00%
Common conditions people have *:
- Type 2 Diabetes: 1 person, 25.00%
- Pain: 1 person, 25.00%
- Osteoporosis (bones weak and more likely to break): 1 person, 25.00%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 25.00%
- Motion Sickness (travel sickness): 1 person, 25.00%
- Insomnia (sleeplessness): 1 person, 25.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 25.00%
- Diabetes: 1 person, 25.00%
- Depression: 1 person, 25.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 25.00%
* Approximation only. Some reports may have incomplete information.
Do you take Cialis and have Dupuytren's contracture?
Check whether Dupuytren's contracture is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Dupuytren's contracture and when was it recovered:
Expand to all the drugs that have ingredients of tadalafil:
Alternative drugs to, pros and cons of Cialis:
- Cialis (26,218 reports)
Common Cialis side effects:
- Abdominal discomfort: 201 reports
- Abdominal distension: 107 reports
- Abdominal pain: 145 reports
- Abdominal pain upper: 181 reports
- Acute kidney failure: 367 reports
- Acute myocardial infarction (acute heart attack): 101 reports
- Anaemia (lack of blood): 168 reports
- Anhedonia (inability to experience pleasure from activities usually found enjoyable): 130 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 152 reports
- Arrhythmias (irregular heartbeat): 182 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 168 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 245 reports
- Back pain: 1,211 reports
- Balance disorder: 133 reports
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 137 reports
- Blindness: 154 reports
- Blindness unilateral: 128 reports
- Blood glucose increased: 142 reports
- Blood testosterone decreased: 688 reports
- Body height decreased: 209 reports
- Breathing difficulty: 524 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 107 reports
- Cardiac disorder: 265 reports
- Cardiac failure congestive: 124 reports
- Chest pain: 407 reports
- Chills (felling of cold): 115 reports
- Chronic kidney disease: 508 reports
- Condition: 110 reports
- Confusional state: 139 reports
- Constipation: 228 reports
- Coronary heart disease (narrowing or blockage of the coronary arteries): 125 reports
- Cough: 223 reports
- Deafness unilateral: 103 reports
- Death: 270 reports
- Dehydration (dryness resulting from the removal of water): 130 reports
- Depressed mood: 340 reports
- Depression: 765 reports
- Diabetes: 530 reports
- Diarrhea: 553 reports
- Dizziness: 771 reports
- Drowsiness: 327 reports
- Drug effect decreased: 129 reports
- Drug ineffective: 4,013 reports
- Dyslipidaemia (abnormal amount of lipids): 156 reports
- Emotional distress: 251 reports
- Enlarged prostate: 626 reports
- Erection increased: 158 reports
- Erection problems: 693 reports
- Eye pain: 109 reports
- Fainting (loss of consciousness and postural tone): 225 reports
- Fall: 299 reports
- Fatigue (feeling of tiredness): 856 reports
- Feeling hot: 134 reports
- Fever: 266 reports
- Gait disturbance: 220 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 362 reports
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 109 reports
- Headache (pain in head): 1,620 reports
- Head injury: 135 reports
- Hearing loss: 144 reports
- Heart attack: 353 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 170 reports
- Heart rate increased: 132 reports
- High blood cholesterol: 889 reports
- High blood pressure: 1,366 reports
- Hyperhidrosis (abnormally increased sweating): 160 reports
- Hypersensitivity: 135 reports
- Hypoaesthesia (reduced sense of touch or sensation): 217 reports
- Hypotension (abnormally low blood pressure): 468 reports
- Indigestion: 377 reports
- Influenza like illness: 117 reports
- Injury: 107 reports
- Insomnia (sleeplessness): 391 reports
- Intentional overdose: 110 reports
- Itching: 172 reports
- Joint pain: 421 reports
- Libido decreased (loss of interest in sex): 344 reports
- Libido disorder (a sexual dysfunction relating to loss of sexual desire): 300 reports
- Loss of consciousness: 220 reports
- Malaise (a feeling of general discomfort or uneasiness): 389 reports
- Malignant melanoma (skin cancer rises from melancytes): 1,288 reports
- Malignant melanoma in situ (early stage of cancer in melanocyte): 317 reports
- Malignant melanoma stage i (cancer has formed; the tumour is not more than 1 millimetre thick, with no ulceration): 156 reports
- Malignant melanoma stage ii (the tumour is either more than 1 but not more than 2 millimetres thick, with ulceration): 108 reports
- Malignant melanoma stage iv (the cancer has spread to other places in the body, such as the lung, liver, brain, bone, soft tissue, or gastrointestinal (gi) tract. cancer may have spread to places in the skin far away from where it first started): 107 reports
- Memory loss: 303 reports
- Metastatic malignant melanoma (spreadable cancer tumour of melanine): 108 reports
- Muscle aches (muscle pain): 560 reports
- Muscle spasms (muscle contraction): 374 reports
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 120 reports
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 103 reports
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 365 reports
- Nasopharyngitis (inflammation of the nasopharynx): 150 reports
- Nausea (feeling of having an urge to vomit): 568 reports
- Nausea and vomiting: 255 reports
- Neuropathy peripheral (surface nerve damage): 108 reports
- Ocular hyperaemia (an abnormally large amount of blood in eye): 130 reports
- Oedema peripheral (superficial swelling): 176 reports
- Optic ischaemic neuropathy (optic nerve damage due to lack of blood supply): 162 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 101 reports
- Overdose: 167 reports
- Pain: 610 reports
- Pain in extremity: 673 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 197 reports
- Penis disorder: 103 reports
- Penis pain: 136 reports
- Peripheral swelling: 118 reports
- Pneumonia: 266 reports
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 184 reports
- Prostate cancer: 237 reports
- Prostatic specific antigen increased: 109 reports
- Pulmonary embolism (blockage of the main artery of the lung): 113 reports
- Rashes (redness): 443 reports
- Renal injury (kidney injury): 101 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 523 reports
- Sleep apnea syndrome: 105 reports
- Sleep disorder: 310 reports
- Stress and anxiety: 632 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 277 reports
- Therapeutic response decreased (less preventive response): 811 reports
- Thrombocytopenia (decrease of platelets in blood): 125 reports
- Tinnitus (a ringing in the ears): 240 reports
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 104 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 144 reports
- Urinary tract infection: 163 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 127 reports
- Vision blurred: 782 reports
- Visual acuity reduced (reduced clearness of vision): 234 reports
- Visual disturbance: 103 reports
- Visual impairment: 323 reports
- Weakness: 1,233 reports
- Weight decreased: 304 reports
- Weight increased: 158 reports
Browse all side effects of Cialis:
a b c d e f g h i j k l m n o p q r s t u v w x y zDupuytren's contracture treatments and more:
- Dupuytren's contracture (2,031 reports)
COVID vaccines that are related to Dupuytren's contracture:
- Dupuytren's contracture in Moderna COVID Vaccine
- Dupuytren's contracture in Pfizer BioNTech Covid Vaccine
- Dupuytren's contracture in Johnson and Johnson Covid Vaccine
Common drugs associated with Dupuytren's contracture:
- Xiaflex: 137 reports
All the drugs that are associated with Dupuytren's contracture:
- Dupuytren's contracture (445 drugs)
Common conditions associated with Dupuytren's contracture:
- Ra: 104 reports
All the conditions that are associated with Dupuytren's contracture:
- Dupuytren's contracture (208 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on tadalafil (the active ingredients of Cialis) and Cialis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Lorazepam and Neonatal Hypoxia - 2 seconds ago
- Para and Amniotic Cavity Infection - 7 seconds ago
- Ankle Fracture and High Blood Cholesterol - 17 seconds ago
- Nifedipine and Jaundice - Yellow Skin - 24 seconds ago
- Sulfatrim and Rituxan drug interaction - 35 seconds ago
- Transderm Scop and Mydriasis - 44 seconds ago
- Gilotrif and Lip Injury - a minute ago
- How effective is Black Cohosh for Menopausal Symptoms? - a minute ago
- Advil and Elavil drug interaction - a minute ago
- Fabrazyme and Ocular Hyperaemia - a minute ago