Ciclosporin and Pneumothorax - a phase IV clinical study of FDA data


Pneumothorax is found among people who take Ciclosporin, especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Ciclosporin and have Pneumothorax. It is created by eHealthMe based on reports of 3,554 people who have side effects when taking Ciclosporin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 04, 2022

3,554 people reported to have side effects when taking Ciclosporin.
Among them, 12 people (0.34%) have Pneumothorax.

What is Ciclosporin?

Ciclosporin has active ingredients of cyclosporine. eHealthMe is studying from 3,565 Ciclosporin users for its effectiveness, alternative drugs and more.

What is Pneumothorax?

Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung) is found to be associated with 1,794 drugs and 1,288 conditions by eHealthMe.

Number of Ciclosporin and Pneumothorax reports submitted per year:

Could Ciclosporin cause Pneumothorax?

Time on Ciclosporin when people have Pneumothorax *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Pneumothorax when taking Ciclosporin *:

  • female: 45.45 %
  • male: 54.55 %

Age of people who have Pneumothorax when taking Ciclosporin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 30 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 40 %
  • 60+: 20 %

Common drugs people take besides Ciclosporin *:

  1. Mitoxantrone: 2 people, 16.67%
  2. Methylprednisolone: 2 people, 16.67%
  3. Methotrexate: 2 people, 16.67%
  4. Metformin: 2 people, 16.67%
  5. Etoposide: 2 people, 16.67%
  6. Cytarabine: 2 people, 16.67%
  7. Cyclophosphamide: 2 people, 16.67%
  8. Amlodipine: 2 people, 16.67%
  9. Acyclovir: 2 people, 16.67%
  10. Vancomycin: 1 person, 8.33%

Common side effects people have besides Pneumothorax *:

  1. Pneumonia: 6 people, 50.00%
  2. Breathing Difficulty: 6 people, 50.00%
  3. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 50.00%
  4. Cough: 5 people, 41.67%
  5. Fever: 5 people, 41.67%
  6. Anaemia (lack of blood): 4 people, 33.33%
  7. Pulmonary Tuberculosis (lungs tuberculosis): 3 people, 25.00%
  8. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 25.00%
  9. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 25.00%
  10. Septic Shock (shock due to blood infection): 3 people, 25.00%

Common conditions people have *:

  1. Tuberculosis Gastrointestinal (a bacterial infection of digestive tract by mycobacterium tuberculosis): 2 people, 16.67%
  2. Immunodeficiency Disorders: 2 people, 16.67%
  3. Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 8.33%
  4. Transplant Rejection (a transplant material is not worked): 1 person, 8.33%
  5. Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 8.33%
  6. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 8.33%
  7. Interstitial Lung Disease: 1 person, 8.33%
  8. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 8.33%
  9. Aplastic Anemia: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ciclosporin and have Pneumothorax?

Check whether Pneumothorax is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Pneumothorax and when was it recovered:

Expand to all the drugs that have ingredients of cyclosporine:

Alternative drugs to, pros and cons of Ciclosporin:

Common Ciclosporin side effects:

Browse all side effects of Ciclosporin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Pneumothorax treatments and more:

COVID vaccines that are related to Pneumothorax:

Common drugs associated with Pneumothorax:

All the drugs that are associated with Pneumothorax:

Common conditions associated with Pneumothorax:

All the conditions that are associated with Pneumothorax:

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Ciclosporin) and Ciclosporin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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