Cimzia and Crohn's disease - a phase IV clinical study of FDA data
Summary:
We study 84,459 people who have side effects when taking Cimzia. Crohn's disease is found, especially among people who are female, 50-59 old, have been taking the drug for 1 - 6 months, also take Humira and have Pain.
The phase IV clinical study analyzes which people take Cimzia and have Crohn's disease. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
84,459 people reported to have side effects when taking Cimzia.
Among them, 3,233 people (3.83%) have Crohn's disease.
What is Cimzia?
Cimzia has active ingredients of certolizumab pegol. It is used in rheumatoid arthritis. Currently, eHealthMe is studying from 101,925 Cimzia users.
What is Crohn's disease?
Crohn's disease (condition that causes inflammation of the gastrointestinal tract) is found to be associated with 2,543 drugs and 2,009 conditions by eHealthMe. Currently, we are studying 361,786 people who have Crohn's disease.
Number of Cimzia and Crohn's disease reports submitted per year:

Time on Cimzia when people have Crohn's disease *:
Gender of people who have Crohn's disease when taking Cimzia*:
Age of people who have Crohn's disease when taking Cimzia *:
Common drugs people take besides Cimzia *:
Common side effects people have besides Crohn's disease *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Cimzia and have Crohn's disease?
Check whether Crohn's disease is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Cimzia side effects by duration, gender and age:
- Cimzia side effects (101,925 reports)
Crohn's disease treatments and more:
- Crohn's disease (361,786 reports)
Common drugs associated with Crohn's disease:
- Humira: 20,999 reports
- Prednisone: 7,967 reports
- Remicade: 7,949 reports
- Accutane: 7,517 reports
- Methotrexate: 4,579 reports
- Stelara: 3,791 reports
- Cimzia: 3,233 reports
- Azathioprine: 2,537 reports
- Imuran: 2,143 reports
- Vitamin d: 2,087 reports
- Pantoprazole: 2,041 reports
- Vitamin b12: 1,975 reports
- Pentasa: 1,718 reports
- Enbrel: 1,590 reports
- Omeprazole: 1,578 reports
- Tylenol: 1,514 reports
- Calcium: 1,385 reports
- Entyvio: 1,272 reports
- Mesalamine: 1,253 reports
- Budesonide: 1,154 reports
- Asacol: 1,123 reports
- Sulfasalazine: 1,115 reports
- Aspirin: 1,090 reports
- Mercaptopurine: 1,068 reports
- Gabapentin: 1,053 reports
- Nexium: 1,021 reports
- Flagyl: 1,002 reports
- Synthroid: 929 reports
- Folic acid: 909 reports
- Prednisolone: 900 reports
- Metronidazole: 851 reports
- Imodium: 821 reports
- Lisinopril: 781 reports
- Orencia: 779 reports
- Xeljanz: 766 reports
- Cosentyx: 757 reports
- Acetaminophen: 749 reports
- Inflectra: 740 reports
- Tramadol: 734 reports
- Tysabri: 700 reports
- Morphine: 676 reports
- Amlodipine: 673 reports
- Wellbutrin: 670 reports
- Metformin: 663 reports
- Vitamins: 661 reports
- Prilosec: 659 reports
- Celebrex: 646 reports
- Leflunomide: 643 reports
- Lomotil: 637 reports
- Cipro: 594 reports
- Ibu: 592 reports
- Clonazepam: 590 reports
- Prevacid: 590 reports
- Benadryl: 589 reports
- Zofran: 578 reports
- Vitamin c: 573 reports
- Oxycodone: 565 reports
- Vitamin d3: 558 reports
- Xanax: 541 reports
- Protonix: 537 reports
- Loraz: 533 reports
- Hydroxychloroquine sulfate: 510 reports
- Methotrexate sodium: 499 reports
- Multivitamin: 499 reports
- Profen: 494 reports
- Ibuprofen: 493 reports
- Cymbalta: 491 reports
- Fosamax: 487 reports
- Zoloft: 485 reports
- Albuterol: 484 reports
- Ondansetron: 471 reports
- Pantoprazole sodium: 470 reports
- Zopiclone: 455 reports
- Magnesium: 452 reports
- Effexor: 450 reports
- Plaquenil: 448 reports
- Hydrochlorothiazide: 442 reports
- Zide: 441 reports
- Codeine: 432 reports
- Percocet: 423 reports
- Lorazepam: 422 reports
- Actemra: 422 reports
- Lyrica: 416 reports
- Fish oil: 409 reports
- Ativan: 403 reports
- Dilaudid: 401 reports
- Potassium: 394 reports
- Lipitor: 393 reports
- Singulair: 386 reports
- Sertraline: 386 reports
- Simponi: 385 reports
- Ergocalciferol: 385 reports
- Atenolol: 384 reports
- Lexapro: 379 reports
- Amnesteem: 371 reports
- Zyrtec: 369 reports
- Prozac: 365 reports
- Ambien: 362 reports
- Celexa: 355 reports
- Simvastatin: 355 reports
- Arava: 354 reports
- Avonex: 352 reports
- Seroquel: 340 reports
- Ortho tri-cyclen: 340 reports
- Nasonex: 335 reports
- Oxycontin: 331 reports
- Lialda: 330 reports
- Zantac: 321 reports
- Solu-medrol: 317 reports
- Allopurinol: 316 reports
- Lansoprazole: 316 reports
- Lopurin: 316 reports
- Desoximetasone: 313 reports
- Ranitidine: 313 reports
- Hydramine: 309 reports
- Tacrolimus: 307 reports
- Symbicort: 306 reports
- Entocort ec: 306 reports
- Diphen: 304 reports
- Benicar: 301 reports
- Phenergan: 297 reports
- Amoxicillin: 293 reports
- Losartan: 290 reports
- Paracetamol: 288 reports
- Hydrocortisone: 281 reports
- Bentyl: 281 reports
- Neurontin: 276 reports
- Spiriva: 275 reports
- Diclofenac: 274 reports
- Paxil: 274 reports
- Morphine sulfate: 272 reports
- Dexilant: 269 reports
- Norvasc: 269 reports
- Claritin: 266 reports
- Ramipril: 266 reports
- Furosemide: 265 reports
- Crestor: 263 reports
- Vicodin: 258 reports
- Advil: 256 reports
- Mirtazapine: 252 reports
- Lasix: 247 reports
- Doxycycline: 242 reports
- Lantus: 241 reports
- Ventolin: 241 reports
- Alprazolam: 234 reports
- Norco: 232 reports
- Fentanyl: 227 reports
- Coumadin: 224 reports
- Mycophenolate mofetil: 222 reports
- Klonopin: 222 reports
- Actonel: 222 reports
- Purinethol: 221 reports
- Spironolactone: 221 reports
- Miralax: 220 reports
- Sotret: 218 reports
- Cholestyramine: 218 reports
- Elavil: 217 reports
- Diazepam: 215 reports
- Benicar hct: 213 reports
- Plavix: 213 reports
- Escitalopram: 208 reports
- Advair hfa: 204 reports
- Fluoxetine: 203 reports
- Probiotic: 202 reports
- Keflex: 195 reports
- Diclofenac sodium: 195 reports
- Bactrim: 193 reports
- Rabeprazole: 193 reports
- Claravis: 193 reports
- Flonase: 192 reports
- Esomeprazole magnesium: 190 reports
- Flexeril: 190 reports
- Valium: 183 reports
- Zithromax: 183 reports
- Allegra: 177 reports
- Pepcid: 176 reports
- Abilify: 171 reports
- Premarin: 169 reports
- Prolia: 166 reports
- Retin-a: 165 reports
- Metoclopramide: 164 reports
- Famotidine: 163 reports
- Zolpidem: 159 reports
- Augmentin: 159 reports
- Apriso: 159 reports
- Solu-cortef: 159 reports
- Celecoxib: 158 reports
- Adderall: 158 reports
- Clonidine: 157 reports
- Biotin: 157 reports
- Promethazine: 156 reports
- Otezla: 155 reports
- Vioxx: 153 reports
- Remeron: 152 reports
- Pregabalin: 152 reports
- Topamax: 152 reports
- Levothyroxine sodium: 152 reports
- Cortisone acetate: 151 reports
- Forteo: 151 reports
- Voltaren: 151 reports
- Flomax: 148 reports
- Melatonin: 148 reports
- Cleocin: 148 reports
- Flovent: 147 reports
- Sandostatin: 146 reports
- Questran: 145 reports
- Eliquis: 144 reports
- Vitamin e: 143 reports
- Trazodone hydrochloride: 143 reports
- Asa: 143 reports
- Meloxicam: 143 reports
- Baclofen: 142 reports
- Alendronate sodium: 140 reports
- Lortab: 139 reports
- Hydromorphone hydrochloride: 139 reports
- Naproxen: 137 reports
- Paroxetine: 137 reports
- Fluconazole: 137 reports
- Carvedilol: 137 reports
- Clopra: 135 reports
- Ursodiol: 134 reports
- Xarelto: 132 reports
- Cyclophosphamide: 132 reports
- Humalog: 131 reports
- Aleve: 130 reports
- Demerol: 129 reports
- Quetiapine fumarate: 128 reports
- Valtrex: 127 reports
- Hydroxyzine: 127 reports
- Rebif: 126 reports
- Reglan: 125 reports
- Cephalexin: 125 reports
- Zocor: 125 reports
- Diflucan: 124 reports
- Temazepam: 123 reports
- Tecfidera: 122 reports
- Gravol: 122 reports
- Erythromycin: 121 reports
- Cortifoam: 119 reports
- Bupropion hydrochloride: 118 reports
- Cetirizine hydrochloride: 118 reports
- Januvia: 117 reports
- Motrin: 115 reports
- Marijuana: 115 reports
- Minocin: 114 reports
- Nystatin: 114 reports
- Temaz: 114 reports
- Tofacitinib citrate: 113 reports
- Sandostatin lar: 113 reports
- Diphenhydramine hydrochloride: 110 reports
- Metoprolol tartrate: 110 reports
- Xolair: 110 reports
- Insulin: 110 reports
- Ultram: 110 reports
- Rituxan: 110 reports
- Methylprednisolone: 109 reports
- Diovan: 109 reports
- Diclofenac potassium: 109 reports
- Centrum: 108 reports
- Carafate: 105 reports
- Levaquin: 105 reports
- Azathioprine sodium: 105 reports
- Nortriptyline hydrochloride: 104 reports
- Bactroban: 104 reports
- Valsartan: 103 reports
- Yasmin: 102 reports
- Buscopan: 102 reports
All the drugs that are associated with Crohn's disease:
- Crohn's disease (2,543 drugs)
Common conditions associated with Crohn's disease:
- Acne: 4,791 reports
- Rheumatoid arthritis: 1,983 reports
- Pain: 1,966 reports
- High blood pressure: 1,807 reports
- Ulcerative colitis: 1,806 reports
- Gastroesophageal reflux disease: 1,386 reports
- Depression: 1,300 reports
- Ankylosing spondylitis: 1,215 reports
- Stress and anxiety: 1,124 reports
- Multiple sclerosis: 1,020 reports
- Psoriasis: 922 reports
- High blood cholesterol: 718 reports
- Asthma: 676 reports
- Vitamin supplementation: 669 reports
- Osteoporosis: 545 reports
- Insomnia: 544 reports
- Birth control: 520 reports
- Diarrhea: 512 reports
- Hypothyroidism: 477 reports
- Arthritis: 454 reports
- Sleep disorder: 447 reports
- Diabetes: 427 reports
- Indigestion: 403 reports
- Abdominal pain: 361 reports
- Migraine: 350 reports
- Joint pain: 313 reports
- Preventive health care: 307 reports
- Headache: 289 reports
- Muscle spasms: 198 reports
- Fibromyalgia: 189 reports
- Type 2 diabetes: 156 reports
- Constipation: 148 reports
- Gastritis: 132 reports
- Neuralgia: 130 reports
- Hormone replacement therapy: 129 reports
- Dry eyes: 128 reports
- Attention deficit hyperactivity disorder: 116 reports
- Chronic obstructive pulmonary disease: 113 reports
- Gastric ulcer: 109 reports
- Narcolepsy: 103 reports
All the conditions that are associated with Crohn's disease:
- Crohn's disease (2,009 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on certolizumab pegol (the active ingredients of Cimzia) and Cimzia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Anzemet and Hydroxyzine drug interaction - now
- Korlym and Semen Volume Decreased - 2 seconds ago
- Pepcid and Econopred drug interaction - 3 seconds ago
- Theophyl and Blood Pressure Management - 6 seconds ago
- Provera and Atrophic Vulvovaginitis - 6 seconds ago
- Questran and Abdominal Pain Upper - 6 seconds ago
- Xtandi and Lotrel drug interaction - 7 seconds ago
- Azulfidine and Gastric Disorder - 10 seconds ago
- Mestinon and Hot Flushes Aggravated - 12 seconds ago
- Belsomra and Diplopia - 13 seconds ago