Cisplatin and Diverticular perforation - from FDA reports


Diverticular perforation is found among people who take Cisplatin, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Taxotere, and have Multiple myeloma. This study is created by eHealthMe based on reports of 51,071 people who have side effects when taking Cisplatin from FDA, and is updated regularly.

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On Aug, 10, 2018

51,071 people reported to have side effects when taking Cisplatin.
Among them, 66 people (0.13%) have Diverticular perforation


Number of reports submitted per year:

Could Cisplatin cause Diverticular perforation?

Time on Cisplatin when people have Diverticular perforation *:

  • < 1 month: 80 %
  • 1 - 6 months: 16 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 4 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Diverticular perforation when taking Cisplatin *:

  • female: 3.03 %
  • male: 96.97 %

Age of people who have Diverticular perforation when taking Cisplatin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 32.31 %
  • 60+: 67.69 %

Top conditions involved for these people *:

  1. Multiple Myeloma (cancer of the plasma cells): 10 people, 15.15%
  2. Nausea (feeling of having an urge to vomit): 8 people, 12.12%
  3. Non-Small Cell Lung Cancer Stage Iv: 6 people, 9.09%
  4. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 9.09%
  5. Pain: 5 people, 7.58%
  6. Infection: 5 people, 7.58%
  7. Anticoagulant Therapy: 5 people, 7.58%
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 5 people, 7.58%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 7.58%
  10. Insomnia (sleeplessness): 5 people, 7.58%
Check whether a drug or a condition causes Diverticular perforation

Top co-used drugs for these people *:

  1. Taxotere: 14 people, 21.21%
  2. Fluorouracil: 12 people, 18.18%
  3. Dexamethasone: 11 people, 16.67%
  4. Combivent: 11 people, 16.67%
  5. Alimta: 10 people, 15.15%
  6. Erbitux: 10 people, 15.15%
  7. Etoposide: 10 people, 15.15%
  8. Cyclophosphamide: 10 people, 15.15%
  9. Velcade: 9 people, 13.64%
  10. Magnesium: 9 people, 13.64%
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Top other side effects for these people *:

  1. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 12 people, 18.18%
  2. Hypotension (abnormally low blood pressure): 10 people, 15.15%
  3. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 10 people, 15.15%
  4. Infectious Peritonitis (inflammation of the peritoneum, typically caused by bacterial infection): 10 people, 15.15%
  5. Constipation: 7 people, 10.61%
  6. Fever: 7 people, 10.61%
  7. Abdominal Abscess (collection of pus in abdomen): 6 people, 9.09%
  8. Pitting Oedema (skin discoloration): 6 people, 9.09%
  9. Nausea (feeling of having an urge to vomit): 6 people, 9.09%
  10. Leukopenia (less number of white blood cells in blood): 6 people, 9.09%
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* Approximation only. Some reports may have incomplete information.

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