Citicoline and Nausea and vomiting - a phase IV clinical study of FDA data


Nausea and vomiting is found among people who take Citicoline, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Citicoline and have Nausea and vomiting. It is created by eHealthMe based on reports of 396 people who have side effects when taking Citicoline from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 01, 2022

396 people reported to have side effects when taking Citicoline.
Among them, 7 people (1.77%) have Nausea and vomiting.

What is Citicoline?

Citicoline has active ingredients of citicoline. eHealthMe is studying from 415 Citicoline users for its effectiveness, alternative drugs and more.

What is Nausea and vomiting?

Nausea and vomiting is found to be associated with 4,595 drugs and 5,408 conditions by eHealthMe.

Number of Citicoline and Nausea and vomiting reports submitted per year:

Could Citicoline cause Nausea and vomiting?

Time on Citicoline when people have Nausea and vomiting *:

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Nausea and vomiting when taking Citicoline *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Nausea and vomiting when taking Citicoline *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 16.67 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 83.33 %

Common drugs people take besides Citicoline *:

  1. Aspirin: 2 people, 28.57%
  2. Baclofen: 2 people, 28.57%
  3. Mirtazapine: 2 people, 28.57%
  4. Ventolin: 1 person, 14.29%
  5. Digoxin: 1 person, 14.29%
  6. Atropine: 1 person, 14.29%
  7. Calcium Gluconate: 1 person, 14.29%
  8. Captopril: 1 person, 14.29%
  9. Ceftriaxone: 1 person, 14.29%
  10. Clopidogrel: 1 person, 14.29%

Common side effects people have besides Nausea and vomiting *:

  1. Nausea (feeling of having an urge to vomit): 2 people, 28.57%
  2. Venous Thrombosis (blood clot (thrombus) that forms within a vein): 1 person, 14.29%
  3. Fall: 1 person, 14.29%
  4. Brain Stem Haemorrhage (bleeding into structures of brain stem): 1 person, 14.29%
  5. Brain Stem Infarction (brainstem stroke): 1 person, 14.29%
  6. Concussion (short loss of normal brain function in response to a head injury): 1 person, 14.29%
  7. Consciousness - Decreased: 1 person, 14.29%
  8. Constipation: 1 person, 14.29%
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 14.29%
  10. Distractibility (inability to sustain one's attention): 1 person, 14.29%

Common conditions people have *:

  1. High Blood Pressure: 2 people, 28.57%
  2. Sleep Disorder: 1 person, 14.29%
  3. Motion Sickness (travel sickness): 1 person, 14.29%
  4. Memory Loss: 1 person, 14.29%
  5. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 14.29%
  6. Joint Pain: 1 person, 14.29%
  7. Cerebral Infarction (less blood supply to brain resulting tissue damage): 1 person, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Citicoline and have Nausea and vomiting?

Check whether Nausea and vomiting is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Nausea and vomiting and when was it recovered:

Expand to all the drugs that have ingredients of citicoline:

Alternative drugs to, pros and cons of Citicoline:

Nausea and vomiting treatments and more:

COVID vaccines that are related to Nausea and vomiting:

Common drugs associated with Nausea and vomiting:

All the drugs that are associated with Nausea and vomiting:

Common conditions associated with Nausea and vomiting:

All the conditions that are associated with Nausea and vomiting:

How the study uses the data?

The study uses data from the FDA. It is based on citicoline (the active ingredients of Citicoline) and Citicoline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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