Cladribine and Thrombocytopenia - from FDA reports

Thrombocytopenia is found among people who take Cladribine, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Cyclophosphamide, and have Acute myeloid leukaemia. This study is created by eHealthMe based on reports of 1,222 people who have side effects when taking Cladribine from FDA, and is updated regularly.

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On Sep, 11, 2018

1,222 people reported to have side effects when taking Cladribine.
Among them, 102 people (8.35%) have Thrombocytopenia

Number of reports submitted per year:

Could Cladribine cause Thrombocytopenia?

Time on Cladribine when people have Thrombocytopenia *:

Gender of people who have Thrombocytopenia when taking Cladribine *:

  • female: 38.82 %
  • male: 61.18 %

Age of people who have Thrombocytopenia when taking Cladribine *:

Top conditions involved for these people *:

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 19 people, 18.63%
  2. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 13 people, 12.75%
  3. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 9 people, 8.82%
  4. Hairy Cell Leukaemia (a type of blood cancer): 9 people, 8.82%
  5. Immunodeficiency Disorders: 9 people, 8.82%

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Top co-used drugs for these people *:

  1. Cyclophosphamide: 12 people, 11.76%
  2. Prednisolone: 10 people, 9.80%
  3. Zevalin: 8 people, 7.84%
  4. Mitoxantrone: 8 people, 7.84%
  5. Cytarabine: 7 people, 6.86%

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Top other side effects for these people *:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 36 people, 35.29%
  2. Anaemia (lack of blood): 32 people, 31.37%
  3. Fever: 22 people, 21.57%
  4. Leukopenia (less number of white blood cells in blood): 18 people, 17.65%
  5. White Blood Cell Count Decreased: 13 people, 12.75%

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* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

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Do you have Thrombocytopenia while taking Cladribine?

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What would happen?

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