Cladribine and Thrombocytopenia - from FDA reports


Thrombocytopenia is found among people who take Cladribine, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Cyclophosphamide, and have Mantle cell lymphoma. This review analyzes which people have Thrombocytopenia with Cladribine. It is created by eHealthMe based on reports of 1,058 people who have side effects when taking Cladribine from FDA , and is updated regularly.



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On Jun, 18, 2018

1,058 people reported to have side effects when taking Cladribine.
Among them, 79 people (7.47%) have Thrombocytopenia


Number of reports submitted per year:

Could Cladribine cause Thrombocytopenia?

Time on Cladribine when people have Thrombocytopenia *:

  • < 1 month: 77.78 %
  • 1 - 6 months: 22.22 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Thrombocytopenia when taking Cladribine *:

  • female: 33.33 %
  • male: 66.67 %

Age of people who have Thrombocytopenia when taking Cladribine *:

  • 0-1: 3.28 %
  • 2-9: 1.64 %
  • 10-19: 3.28 %
  • 20-29: 9.84 %
  • 30-39: 4.92 %
  • 40-49: 11.48 %
  • 50-59: 16.39 %
  • 60+: 49.18 %

Top conditions involved for these people *:

  1. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 13 people, 16.46%
  2. Immunodeficiency Disorders: 9 people, 11.39%
  3. Hairy Cell Leukaemia (a type of blood cancer): 9 people, 11.39%
  4. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 8.86%
  5. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 8.86%
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Top co-used drugs for these people *:

  1. Cyclophosphamide: 12 people, 15.19%
  2. Prednisolone: 10 people, 12.66%
  3. Zevalin: 8 people, 10.13%
  4. Cyclosporine: 7 people, 8.86%
  5. Cytarabine: 7 people, 8.86%
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Top other side effects for these people *:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 34 people, 43.04%
  2. Anaemia (lack of blood): 27 people, 34.18%
  3. Fever: 18 people, 22.78%
  4. White Blood Cell Count Decreased: 12 people, 15.19%
  5. Febrile Neutropenia (fever with reduced white blood cells): 11 people, 13.92%
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* Approximation only. Some reports may have incomplete information.

What's next:

Do you take Cladribine and have Thrombocytopenia?



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