Claritin and Nail discoloration - a phase IV clinical study of FDA data


Nail discoloration is found among people who take Claritin, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Claritin and have Nail discoloration. It is created by eHealthMe based on reports of 64,767 people who have side effects when taking Claritin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 05, 2022

64,767 people reported to have side effects when taking Claritin.
Among them, 19 people (0.03%) have Nail discoloration.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 67,339 Claritin users for its effectiveness, alternative drugs and more.

What is Nail discoloration?

Nail discoloration is found to be associated with 1,274 drugs and 842 conditions by eHealthMe.

Number of Claritin and Nail discoloration reports submitted per year:

Could Claritin cause Nail discoloration?

Time on Claritin when people have Nail discoloration *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Nail discoloration when taking Claritin *:

  • female: 94.12 %
  • male: 5.88 %

Age of people who have Nail discoloration when taking Claritin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 10 %
  • 20-29: 10 %
  • 30-39: 10 %
  • 40-49: 10 %
  • 50-59: 0.0 %
  • 60+: 60 %

Common drugs people take besides Claritin *:

  1. Vitamin C: 5 people, 26.32%
  2. Zejula: 4 people, 21.05%
  3. Calcium: 4 people, 21.05%
  4. Flonase: 4 people, 21.05%
  5. Symbicort: 3 people, 15.79%
  6. Hydrochlorothiazide: 2 people, 10.53%
  7. Nasonex: 2 people, 10.53%
  8. Cardizem Cd: 2 people, 10.53%
  9. Rubraca: 2 people, 10.53%
  10. Metformin: 2 people, 10.53%

Common side effects people have besides Nail discoloration *:

  1. Nausea (feeling of having an urge to vomit): 11 people, 57.89%
  2. Fatigue (feeling of tiredness): 8 people, 42.11%
  3. Pain: 6 people, 31.58%
  4. Hypoaesthesia (reduced sense of touch or sensation): 5 people, 26.32%
  5. Weakness: 5 people, 26.32%
  6. Dizziness: 5 people, 26.32%
  7. Nausea And Vomiting: 5 people, 26.32%
  8. Bone Pain: 5 people, 26.32%
  9. Insomnia (sleeplessness): 5 people, 26.32%
  10. Head Injury: 4 people, 21.05%

Common conditions people have *:

  1. Ovarian Cancer (cancer of ovary): 6 people, 31.58%
  2. Rhinorrhea (watery mucus discharge from the nose): 3 people, 15.79%
  3. Breathing Difficulty: 3 people, 15.79%
  4. Cardiac Disorder: 2 people, 10.53%
  5. High Blood Pressure: 2 people, 10.53%
  6. Anaemia (lack of blood): 2 people, 10.53%
  7. Metastases To Bone (cancer spreads to bone): 1 person, 5.26%
  8. Inflammatory Bowel Disease: 1 person, 5.26%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.26%
  10. Hypotension (abnormally low blood pressure): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin and have Nail discoloration?

Check whether Nail discoloration is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Claritin:

Nail discoloration treatments and more:

COVID vaccines that are related to Nail discoloration:

How severe was Nail discoloration and when was it recovered:

Expand to all the drugs that have ingredients of loratadine:

Common drugs associated with Nail discoloration:

All the drugs that are associated with Nail discoloration:

Common conditions associated with Nail discoloration:

All the conditions that are associated with Nail discoloration:

How the study uses the data?

The study uses data from the FDA. It is based on loratadine (the active ingredients of Claritin) and Claritin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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