Climara and Herniated nucleus pulposus (slipped disk) - a phase IV clinical study of FDA data

Summary:

Herniated nucleus pulposus (slipped disk) is reported only by a few people who take Climara.

The phase IV clinical study analyzes which people take Climara and have Herniated nucleus pulposus (slipped disk). It is created by eHealthMe based on reports of 6,398 people who have side effects while taking Climara from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Feb, 03, 2023

6,398 people reported to have side effects when taking Climara.
Among them, 4 people (0.06%) have Herniated nucleus pulposus (slipped disk).


What is Climara?

Climara has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 6,490 Climara users for its effectiveness, alternative drugs and more.

What is Herniated nucleus pulposus (slipped disk)?

Herniated nucleus pulposus (slipped disk) is found to be associated with 1,402 drugs and 787 conditions by eHealthMe.

Number of Climara and Herniated nucleus pulposus (slipped disk) reports submitted per year:

Could Climara cause Herniated nucleus pulposus (slipped disk)?

Time on Climara when people have Herniated nucleus pulposus (slipped disk) *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Herniated nucleus pulposus (slipped disk) when taking Climara *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Herniated nucleus pulposus (slipped disk) when taking Climara *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 100 %
  • 60+: 0.0 %

Common drugs people take besides Climara *:

  1. Zocor: 2 people, 50.00%
  2. Zanaflex: 2 people, 50.00%
  3. Allegra: 2 people, 50.00%
  4. Aspirin: 2 people, 50.00%
  5. Atarax: 2 people, 50.00%
  6. Avandia: 2 people, 50.00%
  7. Betamethasone Dipropionate: 2 people, 50.00%
  8. Celebrex: 2 people, 50.00%
  9. Estrace: 2 people, 50.00%
  10. Flonase: 2 people, 50.00%

Common side effects people have besides Herniated nucleus pulposus (slipped disk) *:

  1. Back Pain: 4 people, 100.00%
  2. Breathing Difficulty: 4 people, 100.00%
  3. Nausea (feeling of having an urge to vomit): 4 people, 100.00%
  4. Neck Pain: 4 people, 100.00%
  5. Weight Loss: 2 people, 50.00%
  6. Femur Fracture: 2 people, 50.00%
  7. Herpes Zoster: 2 people, 50.00%
  8. Heart Attack: 2 people, 50.00%
  9. Headache (pain in head): 2 people, 50.00%
  10. Head Injury: 2 people, 50.00%

Common conditions people have *:

  1. Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 2 people, 50.00%
  2. Osteoporosis (bones weak and more likely to break): 2 people, 50.00%
  3. Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 50.00%
  4. Hypersensitivity: 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Climara and have Herniated nucleus pulposus (slipped disk)?

Check whether Herniated nucleus pulposus (slipped disk) is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Herniated nucleus pulposus (slipped disk) and when was it recovered:

Expand to all the drugs that have ingredients of estradiol:

Alternative drugs to, pros and cons of Climara:

Common Climara side effects:

Browse all side effects of Climara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Herniated nucleus pulposus (slipped disk) treatments and more:

COVID vaccines that are related to Herniated nucleus pulposus (slipped disk):

Common drugs associated with Herniated nucleus pulposus (slipped disk):

All the drugs that are associated with Herniated nucleus pulposus (slipped disk):

Common conditions associated with Herniated nucleus pulposus (slipped disk):

All the conditions that are associated with Herniated nucleus pulposus (slipped disk):

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Climara) and Climara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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