Clofarabine and Human herpesvirus 6 infection - a phase IV clinical study of FDA data

Summary:

We study 2,536 people who have side effects when taking Clofarabine. Human herpesvirus 6 infection is found, especially among people who are female, 2-9 old, have been taking the drug for < 1 month, also take Morphine and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people take Clofarabine and have Human herpesvirus 6 infection. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 01, 2023

2,536 people reported to have side effects when taking Clofarabine.
Among them, 17 people (0.67%) have Human herpesvirus 6 infection.


What is Clofarabine?

Clofarabine has active ingredients of clofarabine. Currently, eHealthMe is studying from 2,542 Clofarabine users.

What is Human herpesvirus 6 infection?

Human herpesvirus 6 infection is found to be associated with 516 drugs and 445 conditions by eHealthMe. Currently, we are studying 2,316 people who have Human herpesvirus 6 infection.

Number of Clofarabine and Human herpesvirus 6 infection reports submitted per year:

Could Clofarabine cause Human herpesvirus 6 infection?

Time on Clofarabine when people have Human herpesvirus 6 infection *:

  • < 1 month: 88.89 %
  • 1 - 6 months: 11.11 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Human herpesvirus 6 infection when taking Clofarabine *:

  • female: 70.59 %
  • male: 29.41 %

Age of people who have Human herpesvirus 6 infection when taking Clofarabine *:

  • 0-1: 0.0 %
  • 2-9: 38.46 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 7.69 %
  • 40-49: 7.69 %
  • 50-59: 23.08 %
  • 60+: 23.08 %


Common drugs people take besides Clofarabine *:

  1. Morphine: 4 people, 23.53%
  2. Vancomycin: 3 people, 17.65%
  3. Ganciclovir: 3 people, 17.65%
  4. Meropenem: 3 people, 17.65%
  5. Nystatin: 3 people, 17.65%
  6. Acetaminophen: 2 people, 11.76%
  7. Levaquin: 2 people, 11.76%
  8. Fluoxetine: 2 people, 11.76%
  9. Voriconazole: 2 people, 11.76%
  10. Etoposide: 2 people, 11.76%

Common side effects people have besides Human herpesvirus 6 infection *:

  1. Fever: 4 people, 23.53%
  2. Encephalopathy (functioning of the brain is affected by some agent or condition): 3 people, 17.65%
  3. Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 3 people, 17.65%
  4. Mucosal Inflammation (infection of mucous membrane): 3 people, 17.65%
  5. Bk Virus Infection: 3 people, 17.65%
  6. Acinetobacter Infection (infection by group of bacteria commonly found in soil and water): 2 people, 11.76%
  7. Inflammation: 2 people, 11.76%
  8. Escherichia Bacteraemia (presence of bacteria escherichia coli in the blood): 2 people, 11.76%
  9. Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 2 people, 11.76%
  10. Cytomegalovirus Infection: 2 people, 11.76%

Common conditions people have *:

  1. Bone Marrow Conditioning Regimen: 6 people, 35.29%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 29.41%
  3. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 29.41%
  4. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 11.76%
  5. Sedation: 2 people, 11.76%
  6. Leukopenia (less number of white blood cells in blood): 2 people, 11.76%
  7. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 11.76%
  8. Neoplasm Malignant (cancer tumour): 1 person, 5.88%
  9. Diarrhea: 1 person, 5.88%
  10. Chronic Myelomonocytic Leukaemia (cancers of the blood-forming cells of the bone marrow): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Clofarabine and have Human herpesvirus 6 infection?

Check whether Human herpesvirus 6 infection is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Clofarabine side effects by duration, gender and age:

Human herpesvirus 6 infection treatments and more:

Common drugs associated with Human herpesvirus 6 infection:

All the drugs that are associated with Human herpesvirus 6 infection:

Common conditions associated with Human herpesvirus 6 infection:

All the conditions that are associated with Human herpesvirus 6 infection:

How the study uses the data?

The study uses data from the FDA. It is based on clofarabine (the active ingredients of Clofarabine) and Clofarabine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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