Clonazepam and Saliva discoloration - a phase IV clinical study of FDA data


Saliva discoloration is found among people who take Clonazepam, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Clonazepam and have Saliva discoloration. It is created by eHealthMe based on reports of 122,630 people who have side effects when taking Clonazepam from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 28, 2023

122,630 people reported to have side effects when taking Clonazepam.
Among them, 14 people (0.01%) have Saliva discoloration.

What is Clonazepam?

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 128,374 Clonazepam users for its effectiveness, alternative drugs and more.

What is Saliva discoloration?

Saliva discoloration is found to be associated with 289 drugs and 183 conditions by eHealthMe.

Number of Clonazepam and Saliva discoloration reports submitted per year:

Could Clonazepam cause Saliva discoloration?

Gender of people who have Saliva discoloration when taking Clonazepam *:

  • female: 85.71 %
  • male: 14.29 %

Age of people who have Saliva discoloration when taking Clonazepam *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 11.11 %
  • 60+: 77.78 %

Common drugs people take besides Clonazepam *:

  1. Inbrija: 11 people, 78.57%
  2. Rytary: 7 people, 50.00%
  3. Sertraline: 2 people, 14.29%
  4. Neupro: 2 people, 14.29%
  5. Mirapex: 2 people, 14.29%
  6. Triamterene: 1 person, 7.14%
  7. Atenolol: 1 person, 7.14%
  8. Carbidopa: 1 person, 7.14%
  9. Carbidopa And Levodopa: 1 person, 7.14%
  10. Celebrex: 1 person, 7.14%

Common side effects people have besides Saliva discoloration *:

  1. Sputum Discolored: 5 people, 35.71%
  2. Nasal Discharge Discoloration: 5 people, 35.71%
  3. Cough: 5 people, 35.71%
  4. Device Occlusion: 5 people, 35.71%
  5. Oral Mucosal Discoloration: 4 people, 28.57%
  6. Itching: 2 people, 14.29%
  7. Nasal Mucosal Discoloration: 2 people, 14.29%
  8. Nausea (feeling of having an urge to vomit): 2 people, 14.29%
  9. Hoarseness Or Changing Voice: 2 people, 14.29%
  10. Inflammation: 1 person, 7.14%

Common conditions people have *:

  1. Parkinson's Disease: 11 people, 78.57%
  2. On And Off Phenomenon: 11 people, 78.57%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
  4. Asthma: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Clonazepam and have Saliva discoloration?

Check whether Saliva discoloration is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Saliva discoloration and when was it recovered:

Expand to all the drugs that have ingredients of clonazepam:

Alternative drugs to, pros and cons of Clonazepam:

Common Clonazepam side effects:

Browse all side effects of Clonazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Saliva discoloration treatments and more:

COVID vaccines that are related to Saliva discoloration:

All the drugs that are associated with Saliva discoloration:

All the conditions that are associated with Saliva discoloration:

How the study uses the data?

The study uses data from the FDA. It is based on clonazepam (the active ingredients of Clonazepam) and Clonazepam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: