Clonidine and Headache - a phase IV clinical study of FDA data


We study 57,167 people who have side effects when taking Clonidine. Headache is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Tylenol and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people take Clonidine and have Headache. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

On Jul, 20, 2023

57,167 people reported to have side effects when taking Clonidine.
Among them, 3,173 people (5.55%) have Headache.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is used in high blood pressure. Currently, eHealthMe is studying from 62,344 Clonidine users.

What is Headache?

Headache (pain in head) is found to be associated with 5,283 drugs and 5,646 conditions by eHealthMe. Currently, we are studying 714,741 people who have Headache.

Number of Clonidine and Headache reports submitted per year:

Could Clonidine cause Headache?

Time on Clonidine when people have Headache *:

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Gender of people who have Headache when taking Clonidine*:

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Age of people who have Headache when taking Clonidine *:

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Common drugs people take besides Clonidine *:

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Common side effects people have besides Headache *:

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Common conditions people have *:

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* Approximation only. Some reports may have incomplete information.

Do you take Clonidine and have Headache?

Check whether Headache is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Headache and when was it recovered:

Expand to all the drugs that have ingredients of clonidine:

Alternative drugs to, pros and cons of Clonidine:

Browse all side effects of Clonidine:

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Headache treatments and more:

Common drugs associated with Headache:

All the drugs that are associated with Headache:

Common conditions associated with Headache:

All the conditions that are associated with Headache:

How the study uses the data?

The study uses data from the FDA. It is based on clonidine (the active ingredients of Clonidine) and Clonidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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