Clopidogrel and Macular ischaemia - a phase IV clinical study of FDA data


Macular ischaemia is found among people who take Clopidogrel, especially for people who are male, 60+ old.

The phase IV clinical study analyzes which people take Clopidogrel and have Macular ischaemia. It is created by eHealthMe based on reports of 78,666 people who have side effects when taking Clopidogrel from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 03, 2022

78,666 people reported to have side effects when taking Clopidogrel.
Among them, 7 people (0.01%) have Macular ischaemia.

What is Clopidogrel?

Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 79,598 Clopidogrel users for its effectiveness, alternative drugs and more.

What is Macular ischaemia?

Macular ischaemia (broken foveal capillary ring) is found to be associated with 173 drugs and 77 conditions by eHealthMe.

Number of Clopidogrel and Macular ischaemia reports submitted per year:

Could Clopidogrel cause Macular ischaemia?

Gender of people who have Macular ischaemia when taking Clopidogrel *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Macular ischaemia when taking Clopidogrel *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 16.67 %
  • 60+: 83.33 %

Common drugs people take besides Clopidogrel *:

  1. Xarelto: 6 people, 85.71%
  2. Rivaroxaban: 6 people, 85.71%
  3. Acetylsalicylic Acid: 6 people, 85.71%
  4. Tekturna: 1 person, 14.29%
  5. Triesence: 1 person, 14.29%
  6. Ranitidine: 1 person, 14.29%
  7. Ranexa: 1 person, 14.29%
  8. Plavix: 1 person, 14.29%
  9. Novolog: 1 person, 14.29%
  10. Vigamox: 1 person, 14.29%

Common side effects people have besides Macular ischaemia *:

  1. Hemiparesis (weakness on one side of the body): 6 people, 85.71%
  2. Movement - Uncoordinated: 6 people, 85.71%
  3. Brain Stem Infarction (brainstem stroke): 6 people, 85.71%
  4. Diplopia (double vision): 6 people, 85.71%
  5. Dizziness: 6 people, 85.71%
  6. Dyskinesia (abnormality or impairment of voluntary movement): 6 people, 85.71%
  7. Facial Paresis (weakness in facial muscle movement): 6 people, 85.71%
  8. Basilar Artery Thrombosis (blood clot inside a basilar artery): 6 people, 85.71%
  9. Ophthalmoplegia (a paralysis or weakness of one or more of the muscles that control eye movement): 6 people, 85.71%
  10. Paresis Cranial Nerve (condition of muscular weakness due to cranial nerve): 6 people, 85.71%

Common conditions people have *:

  1. Platelet Disorder: 6 people, 85.71%
  2. High Blood Pressure: 6 people, 85.71%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 85.71%
  4. Retinal Oedema (swelling of retina): 1 person, 14.29%
  5. Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 1 person, 14.29%
  6. Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 1 person, 14.29%
  7. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 14.29%
  8. Diabetic Eye Disease: 1 person, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Clopidogrel and have Macular ischaemia?

Check whether Macular ischaemia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Macular ischaemia and when was it recovered:

Expand to all the drugs that have ingredients of clopidogrel:

Alternative drugs to, pros and cons of Clopidogrel:

Common Clopidogrel side effects:

Browse all side effects of Clopidogrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Macular ischaemia treatments and more:

COVID vaccines that are related to Macular ischaemia:

All the drugs that are associated with Macular ischaemia:

All the conditions that are associated with Macular ischaemia:

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel (the active ingredients of Clopidogrel) and Clopidogrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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