Codeine and Gastric ph decreased - a phase IV clinical study of FDA data


Gastric ph decreased is found among people who take Codeine, especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Codeine and have Gastric ph decreased. It is created by eHealthMe based on reports of 33,014 people who have side effects when taking Codeine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

33,014 people reported to have side effects when taking Codeine.
Among them, 88 people (0.27%) have Gastric ph decreased.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 33,615 Codeine users for its effectiveness, alternative drugs and more.

What is Gastric ph decreased?

Gastric ph decreased is found to be associated with 449 drugs and 266 conditions by eHealthMe.

Number of Codeine and Gastric ph decreased reports submitted per year:

Could Codeine cause Gastric ph decreased?

Time on Codeine when people have Gastric ph decreased *:

  • < 1 month: 29.58 %
  • 1 - 6 months: 70.42 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Gastric ph decreased when taking Codeine *:

  • female: 98.84 %
  • male: 1.16 %

Age of people who have Gastric ph decreased when taking Codeine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 31.4 %
  • 30-39: 66.28 %
  • 40-49: 1.16 %
  • 50-59: 1.16 %
  • 60+: 0.0 %

Common drugs people take besides Codeine *:

  1. Omeprazole: 53 people, 60.23%
  2. Clonazepam: 53 people, 60.23%
  3. Diazepam: 53 people, 60.23%
  4. Mirtazapine: 53 people, 60.23%
  5. Lorazepam: 53 people, 60.23%
  6. Quetiapine Fumarate: 24 people, 27.27%
  7. Paroxetine Hydrochloride: 23 people, 26.14%
  8. Paroxetine: 23 people, 26.14%
  9. Tramadol: 21 people, 23.86%
  10. Tramadol Hydrochloride: 15 people, 17.05%

Common side effects people have besides Gastric ph decreased *:

  1. Itching: 88 people, 100.00%
  2. Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 88 people, 100.00%
  3. Drooling (drop saliva uncontrollably from the mouth): 87 people, 98.86%
  4. Visual Impairment: 87 people, 98.86%
  5. Dizziness: 87 people, 98.86%
  6. Urinary Retention (the inability to completely or partially empty the bladder): 87 people, 98.86%
  7. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 87 people, 98.86%
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 87 people, 98.86%
  9. Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 86 people, 97.73%
  10. Skin Discoloration - Bluish (bluish colour of skin): 86 people, 97.73%

Common conditions people have *:

  1. Depression: 78 people, 88.64%
  2. Psychotic Disorder: 78 people, 88.64%
  3. Sedation: 77 people, 87.50%
  4. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 76 people, 86.36%
  5. Indigestion: 69 people, 78.41%
  6. Muscle Spasms (muscle contraction): 69 people, 78.41%
  7. Neck Pain: 67 people, 76.14%
  8. Post-Traumatic Stress Disorder: 66 people, 75.00%
  9. Neuralgia (pain in one or more nerves): 43 people, 48.86%
  10. Oculogyric Crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction): 43 people, 48.86%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine and have Gastric ph decreased?

Check whether Gastric ph decreased is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Gastric ph decreased and when was it recovered:

Expand to all the drugs that have ingredients of codeine sulfate:

Alternative drugs to, pros and cons of Codeine:

Common Codeine side effects:

Browse all side effects of Codeine:

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Gastric ph decreased treatments and more:

COVID vaccines that are related to Gastric ph decreased:

Common drugs associated with Gastric ph decreased:

All the drugs that are associated with Gastric ph decreased:

All the conditions that are associated with Gastric ph decreased:

How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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