Colchicine and Malignant melanoma - a phase IV clinical study of FDA data


Malignant melanoma is found among people who take Colchicine, especially for people who are male, 60+ old.

The phase IV clinical study analyzes which people take Colchicine and have Malignant melanoma. It is created by eHealthMe based on reports of 16,670 people who have side effects when taking Colchicine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 17, 2022

16,670 people reported to have side effects when taking Colchicine.
Among them, 10 people (0.06%) have Malignant melanoma.

What is Colchicine?

Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 14,403 Colchicine users for its effectiveness, alternative drugs and more.

What is Malignant melanoma?

Malignant melanoma (skin cancer rises from melancytes) is found to be associated with 1,131 drugs and 690 conditions by eHealthMe.

Number of Colchicine and Malignant melanoma reports submitted per year:

Could Colchicine cause Malignant melanoma?

Gender of people who have Malignant melanoma when taking Colchicine *:

  • female: 42.86 %
  • male: 57.14 %

Age of people who have Malignant melanoma when taking Colchicine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 0.0 %
  • 60+: 83.33 %

Common drugs people take besides Colchicine *:

  1. Morphine: 3 people, 30.00%
  2. Oxycodone: 3 people, 30.00%
  3. Plavix: 3 people, 30.00%
  4. Uloric: 3 people, 30.00%
  5. Crestor: 3 people, 30.00%
  6. Vitamin B12: 2 people, 20.00%
  7. Mucinex: 2 people, 20.00%
  8. Lasix: 2 people, 20.00%
  9. Jakafi: 2 people, 20.00%
  10. Pantoprazole: 2 people, 20.00%

Common side effects people have besides Malignant melanoma *:

  1. Skin Cancer: 6 people, 60.00%
  2. High Blood Pressure: 4 people, 40.00%
  3. Squamous Cell Carcinoma Of Skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin): 4 people, 40.00%
  4. Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 4 people, 40.00%
  5. Thrombocytopenia (decrease of platelets in blood): 3 people, 30.00%
  6. Fever: 3 people, 30.00%
  7. Back Pain: 3 people, 30.00%
  8. Heart Attack: 3 people, 30.00%
  9. Tendonitis (a condition that causes pain and swelling of tendons): 3 people, 30.00%
  10. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 30.00%

Common conditions people have *:

  1. Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 30.00%
  2. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 20.00%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 20.00%
  4. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 2 people, 20.00%
  5. High Blood Cholesterol: 1 person, 10.00%
  6. Arrhythmias (irregular heartbeat): 1 person, 10.00%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 10.00%
  8. Blood Pressure Fluctuation: 1 person, 10.00%
  9. Cardiac Disorder: 1 person, 10.00%
  10. Chest Pain: 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Colchicine and have Malignant melanoma?

Check whether Malignant melanoma is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Malignant melanoma and when was it recovered:

Expand to all the drugs that have ingredients of colchicine:

Alternative drugs to, pros and cons of Colchicine:

Common Colchicine side effects:

Browse all side effects of Colchicine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Malignant melanoma treatments and more:

COVID vaccines that are related to Malignant melanoma:

Common drugs associated with Malignant melanoma:

All the drugs that are associated with Malignant melanoma:

Common conditions associated with Malignant melanoma:

All the conditions that are associated with Malignant melanoma:

How the study uses the data?

The study uses data from the FDA. It is based on colchicine (the active ingredients of Colchicine) and Colchicine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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