Coq10 and Empty sella syndrome - a phase IV clinical study of FDA data


Empty sella syndrome is reported only by a few people who take Coq10.

The phase IV clinical study analyzes which people take Coq10 and have Empty sella syndrome. It is created by eHealthMe based on reports of 9,057 people who have side effects while taking Coq10 from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

9,057 people reported to have side effects when taking Coq10.
Among them, 4 people (0.04%) have Empty sella syndrome.

What is Coq10?

Coq10 has active ingredients of coenzyme q - 10. It is often used in high blood cholesterol. eHealthMe is studying from 10,053 Coq10 users for its effectiveness, alternative drugs and more.

What is Empty sella syndrome?

Empty sella syndrome (pituitary gland shrinks or becomes flattened) is found to be associated with 306 drugs and 142 conditions by eHealthMe.

Number of Coq10 and Empty sella syndrome reports submitted per year:

Could Coq10 cause Empty sella syndrome?

Gender of people who have Empty sella syndrome when taking Coq10 *:

  • female: 50 %
  • male: 50 %

Age of people who have Empty sella syndrome when taking Coq10 *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 33.33 %
  • 60+: 66.67 %

Common drugs people take besides Coq10 *:

  1. Edecrin: 4 people, 100.00%
  2. Chromium Picolinate: 3 people, 75.00%
  3. Crestor: 3 people, 75.00%
  4. Dexilant: 3 people, 75.00%
  5. Plavix: 3 people, 75.00%
  6. Nexium: 3 people, 75.00%
  7. Fioricet: 3 people, 75.00%
  8. Lyrica: 3 people, 75.00%
  9. Zetia: 1 person, 25.00%
  10. Lenalidomide: 1 person, 25.00%

Common side effects people have besides Empty sella syndrome *:

  1. Diarrhea: 4 people, 100.00%
  2. Weight Decreased: 3 people, 75.00%
  3. Nausea And Vomiting: 3 people, 75.00%
  4. Depression: 3 people, 75.00%
  5. Memory Loss: 3 people, 75.00%
  6. Pneumonia: 3 people, 75.00%
  7. Renal Artery Stenosis (narrowing of renal artery): 3 people, 75.00%
  8. Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 3 people, 75.00%
  9. Sleep Disorder: 3 people, 75.00%
  10. Enlarged Heart: 3 people, 75.00%

Common conditions people have *:

  1. Weakness: 3 people, 75.00%
  2. Migraine (headache): 3 people, 75.00%
  3. Depression: 3 people, 75.00%
  4. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 75.00%
  5. Stress And Anxiety: 3 people, 75.00%
  6. Hair Disorder: 3 people, 75.00%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 75.00%
  8. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 75.00%
  9. Renal Disorder (kidney disease): 3 people, 75.00%
  10. Insomnia (sleeplessness): 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Coq10 and have Empty sella syndrome?

Check whether Empty sella syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Empty sella syndrome and when was it recovered:

Expand to all the drugs that have ingredients of coenzyme q - 10:

Alternative drugs to, pros and cons of Coq10:

Common Coq10 side effects:

Browse all side effects of Coq10:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Empty sella syndrome treatments and more:

COVID vaccines that are related to Empty sella syndrome:

All the drugs that are associated with Empty sella syndrome:

All the conditions that are associated with Empty sella syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on coenzyme q - 10 (the active ingredients of Coq10) and Coq10 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: