Cordarone and Nosebleed - a phase IV clinical study of FDA data

Summary:

We study 22,341 people who have side effects when taking Cordarone. Nosebleed is found, especially among people who are male, 60+ old, have been taking the drug for 2 - 5 years, also take Lasix and have High blood pressure.

The phase IV clinical study analyzes which people take Cordarone and have Nosebleed. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

22,341 people reported to have side effects when taking Cordarone.
Among them, 238 people (1.07%) have Nosebleed.

What is Cordarone?

Cordarone has active ingredients of amiodarone hydrochloride. It is used in atrial fibrillation/flutter. Currently, eHealthMe is studying from 22,466 Cordarone users.

What is Nosebleed?

Nosebleed (bleeding from nose) is found to be associated with 3,374 drugs and 2,994 conditions by eHealthMe. Currently, we are studying 87,755 people who have Nosebleed.

Number of Cordarone and Nosebleed reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Cordarone and have Nosebleed?

Check whether Nosebleed is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .

Related studies

Cordarone side effects by duration, gender and age:

Cordarone side effects (22,466 reports)

Nosebleed treatments and more:

Nosebleed (87,755 reports)

Common drugs associated with Nosebleed:

All the drugs that are associated with Nosebleed:

Nosebleed (3,374 drugs)

Common conditions associated with Nosebleed:

Atrial fibrillation/flutter: 6,595 reports
Stroke: 4,890 reports
High blood pressure: 4,076 reports
Primary pulmonary hypertension: 3,089 reports
Rheumatoid arthritis: 2,972 reports

All the conditions that are associated with Nosebleed:

Nosebleed (2,994 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amiodarone hydrochloride (the active ingredients of Cordarone) and Cordarone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.