Cosopt and Bundle branch block left - a phase IV clinical study of FDA data

Summary:

Bundle branch block left is found among people who take Cosopt, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Cosopt and have Bundle branch block left. It is created by eHealthMe based on reports of 8,216 people who have side effects when taking Cosopt from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 01, 2022

8,216 people reported to have side effects when taking Cosopt.
Among them, 10 people (0.12%) have Bundle branch block left.


What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 8,368 Cosopt users for its effectiveness, alternative drugs and more.

What is Bundle branch block left?

Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle) is found to be associated with 1,345 drugs and 712 conditions by eHealthMe.

Number of Cosopt and Bundle branch block left reports submitted per year:

Could Cosopt cause Bundle branch block left?

Time on Cosopt when people have Bundle branch block left *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Bundle branch block left when taking Cosopt *:

  • female: 60 %
  • male: 40 %

Age of people who have Bundle branch block left when taking Cosopt *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Cosopt *:

  1. Ventolin: 5 people, 50.00%
  2. Actemra: 5 people, 50.00%
  3. Potassium: 3 people, 30.00%
  4. Actonel: 3 people, 30.00%
  5. Lumigan: 2 people, 20.00%
  6. Xalatan: 1 person, 10.00%
  7. Travatan: 1 person, 10.00%
  8. Prednisone: 1 person, 10.00%
  9. Nifedipine: 1 person, 10.00%
  10. Niaspan: 1 person, 10.00%

Common side effects people have besides Bundle branch block left *:

  1. White Blood Cell Count Increased: 5 people, 50.00%
  2. Red Cell Distribution Width Increased: 5 people, 50.00%
  3. Neutrophil Count Increased (excess than normal number of neutrophil a type of blood cell): 5 people, 50.00%
  4. Defaecation Urgency (a sudden compelling urge to defecate): 5 people, 50.00%
  5. High Blood Pressure: 5 people, 50.00%
  6. Weight Increased: 5 people, 50.00%
  7. Dizziness: 5 people, 50.00%
  8. Weight Decreased: 4 people, 40.00%
  9. Cataract (clouding of the lens inside the eye): 3 people, 30.00%
  10. Cellulitis (infection under the skin): 3 people, 30.00%

Common conditions people have *:

  1. Polymyalgia Rheumatica (pain in many muscles): 5 people, 50.00%
  2. Temporal Arteritis (inflammation and damage to blood vessels that supply the head area): 2 people, 20.00%
  3. Weakness: 1 person, 10.00%
  4. Sleep Disorder: 1 person, 10.00%
  5. Pain: 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cosopt and have Bundle branch block left?

Check whether Bundle branch block left is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

Related studies

How severe was Bundle branch block left and when was it recovered:

Expand to all the drugs that have ingredients of dorzolamide hydrochloride; timolol maleate:

Alternative drugs to, pros and cons of Cosopt:

Common Cosopt side effects:

Browse all side effects of Cosopt:

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Bundle branch block left treatments and more:

COVID vaccines that are related to Bundle branch block left:

Common drugs associated with Bundle branch block left:

All the drugs that are associated with Bundle branch block left:

Common conditions associated with Bundle branch block left:

All the conditions that are associated with Bundle branch block left:

How the study uses the data?

The study uses data from the FDA. It is based on dorzolamide hydrochloride; timolol maleate (the active ingredients of Cosopt) and Cosopt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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