Cotrim and Glaucoma - a phase IV clinical study of FDA data


Glaucoma is reported only by a few people who take Cotrim.

The phase IV clinical study analyzes which people take Cotrim and have Glaucoma. It is created by eHealthMe based on reports of 8,580 people who have side effects while taking Cotrim from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 05, 2023

8,580 people reported to have side effects when taking Cotrim.
Among them, 5 people (0.06%) have Glaucoma.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,589 Cotrim users for its effectiveness, alternative drugs and more.

What is Glaucoma?

Glaucoma (increased fluid pressure in the eye with vision loss) is found to be associated with 2,269 drugs and 1,562 conditions by eHealthMe.

Number of Cotrim and Glaucoma reports submitted per year:

Could Cotrim cause Glaucoma?

Time on Cotrim when people have Glaucoma *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Glaucoma when taking Cotrim *:

  • female: 50 %
  • male: 50 %

Age of people who have Glaucoma when taking Cotrim *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 33.33 %
  • 50-59: 66.67 %
  • 60+: 0.0 %

Common drugs people take besides Cotrim *:

  1. Vitamin D3: 1 person, 20.00%
  2. Ventolin: 1 person, 20.00%
  3. Combivent: 1 person, 20.00%
  4. Combivir: 1 person, 20.00%
  5. Doxycycline: 1 person, 20.00%
  6. Fluticasone Propionate: 1 person, 20.00%
  7. Humira: 1 person, 20.00%
  8. Ipratropium Bromide: 1 person, 20.00%
  9. Kaletra: 1 person, 20.00%
  10. Levothyroxine Sodium: 1 person, 20.00%

Common side effects people have besides Glaucoma *:

  1. Visual Field Defect: 1 person, 20.00%
  2. Urine Analysis Abnormal: 1 person, 20.00%
  3. High Blood Pressure: 1 person, 20.00%
  4. Heterophoria (type of eye condition in which the directions that the eyes are pointing at rest position, when not performing binocular fusion): 1 person, 20.00%
  5. Hepatic Lesion: 1 person, 20.00%
  6. Drug Hypersensitivity: 1 person, 20.00%
  7. Dizziness: 1 person, 20.00%
  8. Diplopia (double vision): 1 person, 20.00%
  9. Depression: 1 person, 20.00%
  10. Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 1 person, 20.00%

Common conditions people have *:

  1. Spinal Disorder (disease of spine a back bone): 1 person, 20.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 20.00%
  3. Hiv Infection: 1 person, 20.00%
  4. Anti-Cyclic Citrullinated Peptide Antibody Positive: 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Glaucoma?

Check whether Glaucoma is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Glaucoma and when was it recovered:

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Alternative drugs to, pros and cons of Cotrim:

Common Cotrim side effects:

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Glaucoma treatments and more:

COVID vaccines that are related to Glaucoma:

Common drugs associated with Glaucoma:

All the drugs that are associated with Glaucoma:

Common conditions associated with Glaucoma:

All the conditions that are associated with Glaucoma:

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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